Scott B. Snapper

Biochemistry, Genetics and Molecular Biology · Life Sciences

84h-index32.4kcitations500works2.92yr avg
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Research Topics

Inflammatory Bowel Disease(143), Immunodeficiency and Autoimmune Disorders(109), Immune Cell Function and Interaction(82), Microscopic Colitis(65), IL-33, ST2, and ILC Pathways(56)

Publications492 total

A NOVEL TRUNCATING EP300 MUTATION IMPAIRS INTESTINAL EPITHELIAL DIFFERENTIATION IN PATIENT TISSUE AND ORGANOIDS AND CAN BE RESCUED BY CHEMICAL HDAC INHIBITION
Gastroenterology·2026
Multiomic Immune Profiling of Pediatric Transplant Recipients Identifies Cell States Associated with Vaccine Response
Clinical Journal of the American Society of Nephrology·2025Open Access
A niche-dependent redox rheostat regulates epithelial stem cell fate
Nature Communications·2025· 1 citedOpen Access
Concerted changes in the pediatric single-cell intestinal ecosystem before and after anti-TNF blockade
2025· 1 citedOpen Access
Author response: Concerted changes in the pediatric single-cell intestinal ecosystem before and after anti-TNF blockade
2025Open Access
A Collection of Patient-Derived Intestinal Organoid Lines Reveals Epithelial Phenotypes Associated with Genetic Drivers of Pediatric Inflammatory Bowel Disease
Inflammatory Bowel Diseases·2025Open Access
Divergent T Cell Phenotypes Define Pediatric Crohn’s Disease and Ulcerative Colitis
2025· 1 citedOpen Access
Human colon stem cells are the predominant epithelial responders to bacterial antigens
Frontiers in Immunology·2025· 1 citedOpen Access
Branched actin polymerization drives invasive protrusion formation to promote myoblast fusion during skeletal muscle regeneration
2025Open Access
Author response: Branched actin polymerization drives invasive protrusion formation to promote myoblast fusion during skeletal muscle regeneration
2025Open Access
Gastrointestinal Manifestations of Immunodeficiency
Elsevier eBooks·2025
Phenome-wide association study of monogenic inflammatory bowel disease genes in diverse biobanks identifies population-specific and shared Goldilocks alleles: implications for Precision Medicine.
PubMed·2025
Baseline terminal ileal CT and MRI measurements are associated with imaging outcomes in pediatric Crohn’s disease: a cohort study
Pediatric Radiology·2025Open Access
A collection of patient-derived intestinal organoid lines reveals epithelial pheno-types associated with genetic drivers of pediatric inflammatory bowel disease
2025· 1 citedOpen Access
Distinct heterozygous <i>TTC7A</i> missense variants lead to different intestinal epithelial phenotypes in pediatric IBD
2025Open Access
797: VERY EARLY ONSET INFLAMMATORY BOWEL DISEASE ATLAS REVEALS SIGNATURES OF POLYGENIC AND MONOGENIC DISEASE
Gastroenterology·2025
25: MULTI-ANCESTRY PHEWAS OF MONOGENIC IBD GENES REVEALS ANCESTRY-SPECIFIC EFFECTS IN IBD RISK AND NON-IBD PHENOTYPES
Gastroenterology·2025
561: THE IL1-DEPENDENT TRANSCRIPTION FACTOR MEOX1 AS A DRIVER OF DIFFERENTIATION PROGRAMS IN ACKR1+ ENDOTHELIAL CELLS OF IBD GRANULATION TISSUE
Gastroenterology·2025
Tu2096: SINGLE-CENTER EXPERIENCE OF RISANKIZUMAB IN REFRACTORY PEDIATRIC CROHN’S DISEASE
Gastroenterology·2025
1036: THE BIOGEOGRAPHY OF INFLAMMATION ASSOCIATED FIBROBLASTS IN THE HUMAN AND MOUSE INFLAMED GUT
Gastroenterology·2025
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Frequent Co-authors

Anne M. Griffiths(13), Christoph Klein(12), Aleixo M. Muise(12), Dan Turner(10), Daniel Kotlarz(6), Anthony Otley(6), Dror S. Shouval(6), John K. Marshall(6), Kevan Jacobson(6), David Mack(6), Çharles N. Bernstein(6), Kenneth Croitoru(6), Mark S. Silverberg(6), Holm H. Uhlig(5), Frederick W. Alt(5), Lee A. Denson(5), Thomas D. Walters(5), Francisco J. Quintana(5), Michael Field(5), Paul Moayyedi(5)