Xuanjia Peng

Ministry of Education of the People's Republic of China — China

Biochemistry, Genetics and Molecular Biology · Life Sciences

16h-index525citations60works0.02yr avg
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Research Topics

Chemical Synthesis and Analysis(11), Particle physics theoretical and experimental studies(8), Asymmetric Synthesis and Catalysis(6), Quantum Chromodynamics and Particle Interactions(6), Synthetic Organic Chemistry Methods(6)

Publications50 total

Direct synthesis of 2-(benzylamino)benzoic acids by using benzaldehydes and 2-aminobenzoic acids with catalysis of p-toluenesulfonic acid
Tetrahedron·2025
Discovery of Arylsulfonamide Na <sub>v</sub> 1.7 Inhibitors: IVIVC, MPO Methods, and Optimization of Selectivity Profile
ACS Medicinal Chemistry Letters·2021· 12 citedOpen Access
Selections and screenings of DNA-encoded chemical libraries against enzyme and cellular targets
Bioorganic & Medicinal Chemistry Letters·2021· 33 citedOpen Access
Synthesis of 1,2-Amino Alcohols by Photoredox-Mediated Decarboxylative Coupling of α-Amino Acids and DNA-Conjugated Carbonyls
Organic Letters·2020· 41 cited
DNA-Compatible Copper-Catalyzed Oxidative Amidation of Aldehydes with Non-Nucleophilic Arylamines
Bioconjugate Chemistry·2020· 15 cited
Copper-Mediated DNA-Compatible One-Pot Click Reactions of Alkynes with Aryl Borates and TMS-N<sub>3</sub>
Organic Letters·2020· 31 cited
Solution-Phase DNA-Compatible Pictet-Spengler Reaction Aided by Machine Learning Building Block Filtering
iScience·2020· 19 citedOpen Access
DNA Compatible Intermolecular Wittig Olefination for the Construction of α, β-Unsaturated Carbonyl Compounds
Organic Letters·2020· 21 cited
Palladium-mediated Suzuki-Miyaura Cross-Coupling Reaction of Potassium Boc-protected aminomethyltrifluoroborate with DNA-Conjugated aryl bromides for DNA-Encoded chemical library synthesis
Biochemical and Biophysical Research Communications·2020· 21 cited
Solution Phase DNA-Compatible Pictet-Spengler Reaction Aided by Machine Learning Building Block Filtering
SSRN Electronic Journal·2020Open Access
A Strategy for the Synthesis of Sulfonamides on DNA
Organic Letters·2019· 25 cited
Front Cover: Development of a New Structural Class of Broadly Acting HCV Non‐Nucleoside Inhibitors Leading to the Discovery of MK‐8876 (ChemMedChem 17/2017)
ChemMedChem·2017
Development of a New Structural Class of Broadly Acting HCV Non‐Nucleoside Inhibitors Leading to the Discovery of MK‐8876
ChemMedChem·2017· 17 cited
Discovery of selective, orally bioavailable, N-linked arylsulfonamide Nav1.7 inhibitors with pain efficacy in mice
Bioorganic & Medicinal Chemistry Letters·2017· 45 citedOpen Access
A general approach to access 5,6-dihydroindolo-naphthyridine ring system
Tetrahedron Letters·2017· 5 cited
Design, synthesis, and biological evaluation of anti-EV71 agents
Bioorganic & Medicinal Chemistry Letters·2016· 16 cited
Fragment-wise design of inhibitors to 3C proteinase from enterovirus 71
Biochimica et Biophysica Acta (BBA) - General Subjects·2016· 8 cited
Structure activity relationship of pyridoxazinone substituted RHS analogs of oxabicyclooctane-linked 1,5-naphthyridinyl novel bacterial topoisomerase inhibitors as broad-spectrum antibacterial agents (Part-6)
Bioorganic & Medicinal Chemistry Letters·2015· 17 citedOpen Access
Hydroxy tricyclic 1,5-naphthyridinone oxabicyclooctane-linked novel bacterial topoisomerase inhibitors as broad-spectrum antibacterial agents-SAR of RHS moiety (Part-3)
Bioorganic & Medicinal Chemistry Letters·2015· 22 citedOpen Access
Structure activity relationship of substituted 1,5-naphthyridine analogs of oxabicyclooctane-linked novel bacterial topoisomerase inhibitors as broad-spectrum antibacterial agents (Part-4)
Bioorganic & Medicinal Chemistry Letters·2015· 16 cited
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Frequent Co-authors

K. -S. Yeung(12), Henry Ν. C. Wong(12), Xinfu Pan(11), Hongfang Yang(8), Letian Kuai(8), Xiaohua Hou(8), Xiaodong Shi(7), Weiren Cui(7), Wenji Su(7), Alexander L. Satz(7), Jin Wu(7), Peter T. Meinke(7), David B. Olsen(7), Xuegong She(7), Xiu Wang(6), Ke Li(6), Sheo B. Singh(5), David E. Kaelin(5), Lynn Miesel(5), Christopher M. Tan(5)