Ryan G. Walker

Harvard University — United States

Biochemistry, Genetics and Molecular Biology · Life Sciences

15h-index979citations38works0.02yr avg
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Research Topics

Muscle Physiology and Disorders(16), GDF15 and Related Biomarkers(10), Cardiomyopathy and Myosin Studies(5), Diabetes, Cardiovascular Risks, and Lipoproteins(4), Lipoproteins and Cardiovascular Health(4)

Publications38 total

The crystal structure of the activin B:Fst288 complex and computational insights into the broad antagonistic activity and specificity of follistatin
2025
Identification of shear stress as a potential vasoconduction signal across microvascular networks
Microvascular Research·2025Open Access
Activated GDF11/8 subforms predict cardiovascular events and mortality in humans
Nature Communications·2025Open Access
Identification of shear stress as a potential regulator of the vasoconduction response along microvascular networks
Physiology·2025
Current practice for the chemical immobilisation of non‐domestic feline species: An online survey study
Veterinary Record·2023· 1 citedOpen Access
GDF11 and aging biology - controversies resolved and pending
The Journal of Cardiovascular Aging·2023· 10 citedOpen Access
Functional substitutions of amino acids that differ between GDF11 and GDF8 impact skeletal development and skeletal muscle
Life Science Alliance·2023· 8 citedOpen Access
Functional substitutions of amino acids that differ between GDF11 and GDF8 impact skeletal development and skeletal muscle
2022Open Access
Heparin-mediated dimerization of follistatin
Experimental Biology and Medicine·2020· 7 citedOpen Access
Exogenous GDF11, but not GDF8, reduces body weight and improves glucose homeostasis in mice
Scientific Reports·2020· 24 citedOpen Access
Variation in zygotic CRISPR/Cas9 gene editing outcomes generates novel reporter and deletion alleles at the Gdf11 locus
Scientific Reports·2019· 7 citedOpen Access
Analysis of Cre-mediated genetic deletion of <i>Gdf11</i> in cardiomyocytes of young mice
American Journal of Physiology-Heart and Circulatory Physiology·2019· 19 citedOpen Access
Crystal structure of the WFIKKN2 follistatin domain reveals insight into how it inhibits growth differentiation factor 8 (GDF8) and GDF11
Journal of Biological Chemistry·2019· 16 citedOpen Access
Co-storage and release of insulin-like peptide-5, glucagon-like peptide-1 and peptideYY from murine and human colonic enteroendocrine cells
Molecular Metabolism·2018· 66 citedOpen Access
New Insight Into Hyperemesis Gravidarum and a Potential Role for GDF15
Endocrinology·2018· 2 citedOpen Access
Molecular characterization of latent GDF8 reveals mechanisms of activation
Proceedings of the National Academy of Sciences·2018· 36 citedOpen Access
A consensus model of human apolipoprotein A-I in its monomeric and lipid-free state
Nature Structural & Molecular Biology·2017· 72 citedOpen Access
Molecular characterization of latent GDF8 reveals mechanisms of activation
2017· 5 citedOpen Access
Structural basis for potency differences between GDF8 and GDF11
BMC Biology·2017· 118 citedOpen Access
Structural and biochemical studies on ligands and antagonists within the transforming growth factor ß family
OhioLink ETD Center (Ohio Library and Information Network)·2016Open Access
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Frequent Co-authors

Thomas B. Thompson(24), Richard Lee(12), Amy J. Wagers(10), Melanie J. Mills(6), Ana Vujić(5), Jill M. Goldstein(5), Jamie Morris(5), W. Sean Davidson(5), Jason C. McCoy(4), John Melchior(4), Martin K. Jones(4), Jere P. Segrest(4), Kourtney R. Mendello(4), Chandramohan Kattamuri(4), Tommaso Poggioli(3), Lee L. Rubin(3), Miook Cho(3), Magdalena Czepnik(3), Erich J. Goebel(3), Kelly L. Walton(3)