R. M. PURICK

Merck & Co., Inc., Rahway, NJ, USA (United States) — United States

Biochemistry, Genetics and Molecular Biology · Life Sciences

8h-index461citations17works0.02yr avg
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Research Topics

Chemical Synthesis and Analysis(5), Synthesis and Catalytic Reactions(5), Chemical Synthesis and Reactions(3), Asymmetric Synthesis and Catalysis(2), HIV/AIDS drug development and treatment(2)

Publications17 total

A convergent asymmetric synthesis of a growth hormone secretagogue
Tetrahedron Asymmetry·2003· 16 cited
ChemInform Abstract: Cyclic Imidate Salts in Acyclic Stereochemistry: Diastereoselective syn‐Epoxidation of 2‐Alkyl‐4‐enamides to Epoxyamides.
ChemInform·1996
Cyclic imidate salts in acyclic stereochemistry: Diastereoselective syn-epoxidation of 2-alkyl-4-enamides to epoxyamides
Tetrahedron·1996· 31 cited
ChemInform Abstract: Diastereoselective syn‐Epoxidation of 2‐Alkyl‐4‐enamides to Epoxyamides: Synthesis of the Merck HIV‐1 Protease Inhibitor Epoxide Intermediate.
ChemInform·1995
Diastereoselective syn-epoxidation of 2-alkyl-4-enamides to epoxyamides: Synthesis of the Merck HIV-1 protease inhibitor epoxide intermediate
Tetrahedron Letters·1995· 68 cited
ChemInform Abstract: An Efficient Asymmetric Synthesis of (R)‐3‐Amino‐2,3,4,5‐tetrahydro‐1H‐ (1)benzazepin‐2‐one.
ChemInform·1994
ChemInform Abstract: Highly Diastereoselective Reaction of a Chiral, Non‐Racemic Amide Enolate with (S)‐Glycidyl Tosylate. Synthesis of the Orally Active HIV‐ 1 Protease Inhibitor L‐735,524
ChemInform·1994
An efficient asymmetric synthesis of (R)-3-amino-2,3,4,5-tetrahydro-1H-[1]benzazepin-2-one
Tetrahedron Letters·1994· 55 cited
Highly diastereoselective reaction of a chiral, non-racemic amide enolate with (S)-glycidyl tosylate. Synthesis of the orally active HIV-1 protease inhibitor L-735,524
Tetrahedron Letters·1994· 149 cited
ChemInform Abstract: A Stereocontrolled Synthesis of an Important Intermediate for the Preparation of 1β‐Methylcarbapenem Antibiotics.
ChemInform·1987
Stereocontrolled synthesis of an important intermediate for the preparation of 1.beta.-methylcarbapenem antibiotics
The Journal of Organic Chemistry·1987· 35 cited
ChemInform Abstract: NEW ASPECTS OF INTRAMOLECULAR HYDROGEN TRANSFER IN SOME ORTHO‐SUBSTITUTED ARYL RADICALS
Chemischer Informationsdienst·1978
New aspects of intramolecular hydrogen transfer in some ortho-substituted aryl radicals
The Journal of Organic Chemistry·1978· 21 cited
ChemInform Abstract: A NEW AND SIMPLE METHOD OF RESOLUTION. PREPARATION OF 3‐FLUORO‐D‐ALANINE‐2‐D
Chemischer Informationsdienst·1977
A new and simple method of resolution. Preparation of 3-fluoro-D-alanine-2-d
The Journal of Organic Chemistry·1977· 8 cited
ChemInform Abstract: EINE NEUE SYNTHESE DES ANTIBIOTICUMS PHOSPHONOMYCIN
Chemischer Informationsdienst Organische Chemie·1971
New synthesis of the antibiotic phosphonomycin
The Journal of Organic Chemistry·1970· 78 cited

Frequent Co-authors

Kan K. Eng(9), R. P. Volante(9), Robert A. Reamer(8), Kai Rossen(6), Paul J. Reider(6), D. Askin(6), George Gal(5), Peter E. Maligres(4), Veena Upadhyay(4), Steven J. Cianciosi(4), Jennifer Keller(3), Frederick W. Hartner(3), David Askin(2), Kenneth M. Wells(2), Edward J. Glamkowski(2), M. Sletzinger(2), Joseph D. Armstrong(2), Woo‐Baeg Choi(2), L. M. FUENTES(2), I. Shinkai(2)