Svetlana Gaidarova

Thomas Jefferson University — United States

Medicine · Health Sciences

23h-index3.6kcitations66works0.02yr avg
OpenAlex↗ORCID↗Google Scholar↗Lab page↗

Accepting Students?

No reports yet. Know if this professor is taking students?

Research Topics

CAR-T cell therapy research(37), Immune Cell Function and Interaction(25), Multiple Myeloma Research and Treatments(15), CRISPR and Genetic Engineering(13), Protein Degradation and Inhibitors(8)

Publications66 total

COL1A1 proximal promoter topology regulates its transcriptional response to transforming growth factor β
Connective Tissue Research·2024Open Access
Data from GSK3 Inhibition Drives Maturation of NK Cells and Enhances Their Antitumor Activity
2023Open Access
Supplemental Figures 1-6 from GSK3 Inhibition Drives Maturation of NK Cells and Enhances Their Antitumor Activity
2023Open Access
Data from GSK3 Inhibition Drives Maturation of NK Cells and Enhances Their Antitumor Activity
2023Open Access
Supplemental Figures 1-6 from GSK3 Inhibition Drives Maturation of NK Cells and Enhances Their Antitumor Activity
2023Open Access
Quadruple gene-engineered natural killer cells enable multi-antigen targeting for durable antitumor activity against multiple myeloma
Nature Communications·2022· 71 citedOpen Access
High-Density Cryopreservation of Off-the-Shelf CAR-NK Cells Facilitates On-demand Treatment Access
Blood·2022· 1 cited
Dual antigen–targeted off-the-shelf NK cells show durable response and prevent antigen escape in lymphoma and leukemia
Blood·2022· 79 citedOpen Access
Off-the-Shelf, Multiplexed-Engineered iPSC-Derived NK Cells Mediate Potent Multi-Antigen Targeting of B-Cell Malignancies with Reduced Cytotoxicity Against Healthy B Cells
Blood·2021· 9 cited
117 FT536 Path to IND: Ubiquitous targeting of solid tumors with an off-the-shelf, first-of-kind MICA/B-specific CAR-iNK cellular immunotherapy
Regular and Young Investigator Award Abstracts·2021· 3 citedOpen Access
Harnessing features of adaptive NK cells to generate iPSC-derived NK cells for enhanced immunotherapy
Cell stem cell·2021· 147 citedOpen Access
Abstract 1539: Development of off-the-shelf B7H3 chimeric antigen receptor NK cell therapeutic with broad applicability across many solid tumors
Cancer Research·2021· 3 cited
Abstract 1550: FT576 path to first-of-kind clinical trial: translation of a versatile multi-antigen specific off-the-shelf NK cell for treatment of multiple myeloma
Cancer Research·2021· 9 cited
CAR19 iPSC-Derived NK Cells Utilize the Innate Functional Potential Mediated through NKG2A-Driven Education and Override the HLA-E Check Point to Effectively Target B Cell Lymphoma
Blood·2020· 3 cited
Development of a Novel MICA/B-Specific CAR As a Pan-Tumor Targeting Strategy for Off-the-Shelf, Cell-Based Cancer Immunotherapy
Blood·2020· 2 cited
FT576: Multi-Specific Off-the-Shelf CAR-NK Cell Therapy Engineered for Enhanced Persistence, Avoidance of Self-Fratricide and Optimized Mab Combination Therapy to Prevent Antigenic Escape and Elicit a Deep and Durable Response in Multiple Myeloma
Blood·2020· 40 cited
iPSC-derived NK cells maintain high cytotoxicity and enhance in vivo tumor control in concert with T cells and anti–PD-1 therapy
Science Translational Medicine·2020· 235 citedOpen Access
114 Preclinical development of a novel iPSC-derived CAR-MICA/B NK cell immunotherapy to overcome solid tumor escape from NKG2D-mediated mechanisms of recognition and killing
Regular and Young Investigator Award Abstracts·2020· 1 citedOpen Access
470 Targeting Pan-Tumor Associated Antigen B7H3 via Combination of Tri-specific Killer Engager and Off-the-shelf NK Cell Therapy Enhances Specificity and Function Against a Broad Range of Solid Tumors
Regular and Young Investigator Award Abstracts·2020· 3 citedOpen Access
Abstract 2216: Combinational strategy targeting B cell malignancy using iPSC engineered CAR-NK (FT596) and CAR-T cell (FT819) platforms with therapeutic antibody to achieve an effective deep and durable response
Cancer Research·2020· 1 cited
page 1 of 4Next →

Frequent Co-authors

Ryan Bjordahl(27), Bahram Valamehr(27), Jeffrey S. Miller(20), Frank Cichocki(19), Sajid Mahmood(15), Antonia Lopez‐Girona(13), Ramzey Abujarour(13), Greg Bonello(13), Paul Rogers(12), Dan S. Kaufman(12), Tom Lee(12), Hui-Yi Chu(11), Brian Groff(11), Robert Blum(10), Bruce Walcheck(10), Janel Huffman(9), Karl‐Johan Malmberg(9), Jode Goodridge(8), Zachary Davis(7), Derek Mendy(6)