Eva Frei

Pharmacology, Toxicology and Pharmaceutics · Life Sciences

46h-index6.7kcitations282works0.02yr avg
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Research Topics

Pharmacogenetics and Drug Metabolism(67), Cancer therapeutics and mechanisms(51), Carcinogens and Genotoxicity Assessment(35), Drug-Induced Hepatotoxicity and Protection(35), Nephrotoxicity and Medicinal Plants(33)

Publications282 total

12 Tables, 3 Figure from Environmental Pollutant and Potent Mutagen 3-Nitrobenzanthrone Forms DNA Adducts after Reduction by NAD(P)H:Quinone Oxidoreductase and Conjugation by Acetyltransferases and Sulfotransferases in Human Hepatic Cytosols
2023Open Access
Data from Environmental Pollutant and Potent Mutagen 3-Nitrobenzanthrone Forms DNA Adducts after Reduction by NAD(P)H:Quinone Oxidoreductase and Conjugation by Acetyltransferases and Sulfotransferases in Human Hepatic Cytosols
2023Open Access
Data from Environmental Pollutant and Potent Mutagen 3-Nitrobenzanthrone Forms DNA Adducts after Reduction by NAD(P)H:Quinone Oxidoreductase and Conjugation by Acetyltransferases and Sulfotransferases in Human Hepatic Cytosols
2023Open Access
12 Tables, 3 Figure from Environmental Pollutant and Potent Mutagen 3-Nitrobenzanthrone Forms DNA Adducts after Reduction by NAD(P)H:Quinone Oxidoreductase and Conjugation by Acetyltransferases and Sulfotransferases in Human Hepatic Cytosols
2023Open Access
Transformation of Mangiferin to Norathyriol by Human Fecal Matrix in Anaerobic Conditions: Comprehensive NMR of the Xanthone Metabolites, Antioxidant Capacity, and Comparative Cytotoxicity Against Cancer Cell Lines
Natural Product Communications·2020· 9 citedOpen Access
Expression Patterns of Xenobiotic-Metabolizing Enzymes in Tumor and Adjacent Normal Mucosa Tissues among Patients with Colorectal Cancer: The ColoCare Study
Cancer Epidemiology Biomarkers & Prevention·2019· 24 citedOpen Access
Der Auftrag der Fachhochschulen - Erhöhung der Innovationskraft von Gesellschaft und Wirtschaft : Möglichkeiten der Zusammenarbeit zwischen Hochschule und Wirtschaft illustriert an Beispielen
Zürcher Hochschule für Angewandte Wissenschaften digital collection (Zurich University of Applied Sciences)·2018
The Histone Deacetylase Inhibitor Valproic Acid Exerts a Synergistic Cytotoxicity with the DNA-Damaging Drug Ellipticine in Neuroblastoma Cells
International Journal of Molecular Sciences·2018· 23 citedOpen Access
FairCare : the network based solution for collaborative future care : AAL final project report
Zürcher Hochschule für Angewandte Wissenschaften digital collection (Zurich University of Applied Sciences)·2018
Comparison of the oxidation of carcinogenic aristolochic acid I and II by microsomal cytochromes P450 in vitro: experimental and theoretical approaches
Monatshefte für Chemie - Chemical Monthly·2017· 19 citedOpen Access
Erratum to: Induced expression of microsomal cytochrome b 5 determined at mRNA and protein levels in rats exposed to ellipticine, benzo[a]pyrene, and 1-phenylazo-2-naphthol (Sudan I)
Monatshefte für Chemie - Chemical Monthly·2017Open Access
Comparison of human cytochrome P450 1A1-catalysed oxidation of benzo[a]pyrene in prokaryotic and eukaryotic expression systems
Monatshefte für Chemie - Chemical Monthly·2017· 11 citedOpen Access
Cytochrome b 5 plays a dual role in the reaction cycle of cytochrome P450 3A4 during oxidation of the anticancer drug ellipticine
Monatshefte für Chemie - Chemical Monthly·2017· 16 citedOpen Access
FairCare - die Vermittlung von formeller und informeller Pflege für ältere Menschen optimieren : EU-Forschungsprojekt aus dem AAL Programm
Zürcher Hochschule für Angewandte Wissenschaften digital collection (Zurich University of Applied Sciences)·2017
Effectiveness of human cytochrome P450 3A4 present in liposomal and microsomal nanoparticles in formation of covalent DNA adducts by ellipticine.
PubMed·2016· 1 cited
NADH:cytochrome b5 reductase and cytochrome b5 act as sole electron donors to human cytochrome P450 1A1-catalyzed oxidation and DNA adduct formation by benzo[a]pyrene
Toxicology Letters·2016
Correction to NADH:Cytochrome <i>b</i><sub>5</sub> Reductase and Cytochrome <i>b</i><sub>5</sub> Can Act as Sole Electron Donors to Human Cytochrome P450 1A1-Mediated Oxidation and DNA Adduct Formation by Benzo[<i>a</i>]pyrene
Chemical Research in Toxicology·2016· 1 citedOpen Access
NADH:Cytochrome <i>b</i><sub>5</sub> Reductase and Cytochrome <i>b</i><sub>5</sub> Can Act as Sole Electron Donors to Human Cytochrome P450 1A1-Mediated Oxidation and DNA Adduct Formation by Benzo[<i>a</i>]pyrene
Chemical Research in Toxicology·2016· 36 citedOpen Access
NADPH- and NADH-dependent metabolism of and DNA adduct formation by benzo[a]pyrene catalyzed with rat hepatic microsomes and cytochrome P450 1A1
Monatshefte für Chemie - Chemical Monthly·2016· 12 citedOpen Access
The impact of individual cytochrome P450 enzymes on oxidative metabolism of benzo[<i>a</i>]pyrene in human livers
Environmental and Molecular Mutagenesis·2016· 77 citedOpen Access
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Frequent Co-authors

Marie Stiborová(37), Heinz H. Schmeiser(18), Volker M. Arlt(14), Manfred Wießler(11), David H. Phillips(8), Václav Martínek(6), René Kizek(5), Colin J. Henderson(5), C. Roland Wolf(5), Jitka Poljaková(5), Michaela Moserová(5), Petr Hodek(4), Christian A. Bieler(4), Tomáš Eckschlager(4), Andrea Breuer(4), Jan Hraběta(3), Dagmar Aimová(3), Lucie Bořek-Dohalská(3), Martina Rupertová(3), Jiřı́ Hudeček(3)