Daniel W. Pack

University of Kentucky — United States

Biochemistry, Genetics and Molecular Biology · Life Sciences

44h-index10.9kcitations116works2.52yr avg
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Research Topics

RNA Interference and Gene Delivery(45), Virus-based gene therapy research(24), Advanced Drug Delivery Systems(23), Advanced biosensing and bioanalysis techniques(22), Nanoparticle-Based Drug Delivery(15)

Publications116 total

Impact of Acetylation, Succinylation, and pH on DNA Packaging in PEI-Based Polyplexes
Biomacromolecules·2024· 3 cited
Impact of Acetylation, Succinylation, and pH on PEI-Based Polyplex Structure and Function
2024· 2 citedOpen Access
Polymer/Nanoceria Hybrid Polyplexes for Gene and Antioxidant Delivery
ACS Applied Bio Materials·2023· 2 cited
Effect of polyplex surface charge on cellular internalization and intracellular trafficking
Journal of Drug Delivery Science and Technology·2023· 10 cited
Effect of Polyplex Surface Charge on Cellular Internalization and Intracellular Trafficking
SSRN Electronic Journal·2023Open Access
Enhanced Gene Delivery and CRISPR/Cas9 Homology-Directed Repair in Serum by Minimally Succinylated Polyethylenimine
Molecular Pharmaceutics·2021· 13 cited
Cyanuric chloride as the basis for compositionally diverse lipids
RSC Advances·2021· 7 citedOpen Access
Succinylated Polyethylenimine Derivatives Greatly Enhance Polyplex Serum Stability and Gene Delivery In Vitro
Biomacromolecules·2018· 30 cited
Evaluation of FOXC1 as a therapeutic target for basal-like breast cancer
Cancer Gene Therapy·2018· 7 cited
Prospects of siRNA applications in regenerative medicine
International Journal of Pharmaceutics·2017· 36 cited
Rapid and facile quantitation of polyplex endocytic trafficking
Journal of Controlled Release·2017· 9 cited
Endocytic Transport of Polyplex and Lipoplex siRNA Vectors in HeLa Cells
Pharmaceutical Research·2016· 22 cited
Derivation of an Analytical Solution to a Reaction-Diffusion Model for Autocatalytic Degradation and Erosion in Polymer Microspheres
PLoS ONE·2015· 22 citedOpen Access
Intracellular trafficking of hybrid gene delivery vectors
Journal of Controlled Release·2015· 18 citedOpen Access
Optimal spatial field control for controlled release
Optimal Control Applications and Methods·2015
[2014] Keswani Su Pack Hybrid biopolymer nanovectors JCR PMC
2015
The effect of glycosaminoglycan content on polyethylenimine-based gene delivery within three-dimensional collagen-GAG scaffolds
Biomaterials Science·2015· 20 citedOpen Access
Dependence of PEI and PAMAM Gene Delivery on Clathrin- and Caveolin-Dependent Trafficking Pathways
Pharmaceutical Research·2014· 44 cited
Uniform biodegradable microparticle systems for controlled release
Chemical Engineering Science·2014· 44 cited
Efficient in vitro gene delivery by hybrid biopolymer/virus nanobiovectors
Journal of Controlled Release·2014· 13 citedOpen Access
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Frequent Co-authors

Nathan P. Gabrielson(8), Cory Berkland(6), Kyekyoon Kim(6), Frances H. Arnold(5), Emily J. Pollauf(5), Qingxing Xu(5), M. Laird Forrest(4), Kyekyoon Kevin Kim(4), David K. Smith(4), Chi‐Hwa Wang(4), David Putnam(3), Róbert Langer(3), Cory Berkland(3), Darryl Y. Sasaki(3), Shy Chyi Wuang(3), K. G. Neoh(3), E. T. Kang(3), Deborah Leckband(3), Yujie Xia(3), Patrick S. Stayton(2)