Henri C. Wals

Solvay (Belgium) — Belgium

Medicine · Health Sciences

9h-index579citations17works0.02yr avg
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Research Topics

Cannabis and Cannabinoid Research(10), Pharmacological Receptor Mechanisms and Effects(8), Neurotransmitter Receptor Influence on Behavior(7), Synthesis of heterocyclic compounds(4), Neuroscience and Neuropharmacology Research(3)

Publications17 total

Two distinct classes of novel pyrazolinecarboxamides as potent cannabinoid CB1 receptor agonists
Bioorganic & Medicinal Chemistry Letters·2010· 22 citedOpen Access
ChemInform Abstract: Synthesis, SAR and Intramolecular Hydrogen Bonding Pattern of 1,3,5‐Trisubstituted 4,5‐Dihydropyrazoles as Potent Cannabinoid CB<sub>1</sub> Receptor Antagonists.
ChemInform·2010
Synthesis, SAR and intramolecular hydrogen bonding pattern of 1,3,5-trisubstituted 4,5-dihydropyrazoles as potent cannabinoid CB1 receptor antagonists
Bioorganic & Medicinal Chemistry Letters·2010· 19 citedOpen Access
CCDC 760300: Experimental Crystal Structure Determination
The Cambridge Structural Database·2010Open Access
Synthesis and SAR of novel imidazoles as potent and selective cannabinoid CB2 receptor antagonists with high binding efficiencies
Bioorganic & Medicinal Chemistry Letters·2009· 27 citedOpen Access
Novel 3,4‐Diarylpyrazolines as Potent Cannabinoid CB<sub>1</sub> Receptor Antagonists with Lower Lipophilicity.
ChemInform·2006
Novel 3,4-diarylpyrazolines as potent cannabinoid CB1 receptor antagonists with lower lipophilicity
Bioorganic & Medicinal Chemistry Letters·2005· 61 citedOpen Access
Bioisosteric Replacements of the Pyrazole Moiety of Rimonabant:  Synthesis, Biological Properties, and Molecular Modeling Investigations of Thiazoles, Triazoles, and Imidazoles as Potent and Selective CB<sub>1</sub>Cannabinoid Receptor Antagonists
Journal of Medicinal Chemistry·2004· 177 citedOpen Access
Synthesis, Biological Properties, and Molecular Modeling Investigations of Novel 3,4-Diarylpyrazolines as Potent and Selective CB<sub>1</sub> Cannabinoid Receptor Antagonists
Journal of Medicinal Chemistry·2003· 186 citedOpen Access
Design, Synthesis and Biological Activity of Rigid Cannabinoid CB<sub>1</sub> Receptor Antagonists.
ChemInform·2003
Design, Synthesis and Biological Activity of Rigid Cannabinoid CB1 Receptor Antagonists.
Chemical and Pharmaceutical Bulletin·2002· 61 citedOpen Access
ChemInform Abstract: Regioselective Aminomethylations of Bicyclic Phenols.
ChemInform·2000
Regioselective Aminomethylations of Bicyclic Phenols
Heterocycles·2000· 9 citedOpen Access
ChemInform Abstract: Two Novel Syntheses of the Histamine H3 Antagonist Thioperamide (VII).
ChemInform·1996· 1 cited
Two novel syntheses of the histamine H3 antagonist thioperamide
Tetrahedron·1995· 9 cited
ChemInform Abstract: Synthesis of 2‐(Alkylthio)‐ and 2‐(Arylthio)‐3‐cyanothiophenes. Nucleophilic Displacement of the Alkylsulfinyl Group by Thiols.
ChemInform·1989
The synthesis of 2-(alkylthio)- and 2-(arylthio)-3-cyanothiophenes. The nucleophilic displacement of the alkylsulfinyl group by thiols.
Tetrahedron·1988· 7 cited

Frequent Co-authors

Jos H.M. Lange(15), Herman H. van Stuivenberg(10), Chris G. Kruse(8), Arnold P. den Hartog(7), Willem Veerman(6), Martina A.W. van der Neut(5), Bernard J. Van Vliet(5), Hein K. A. C. Coolen(4), Andrew C. McCreary(4), Tiny J. P. Adolfs(4), Jessica Adriana Rigtje Dijksman(3), Eric Ronken(3), Koos Tipker(3), Bob Stork(3), Jan Hoogendoorn(3), Hiskias G. Keizer(2), Peter C. Verveer(2), Alice J. M. Borst(2), Axel R. Stoit(2), Arie Mulder(2)