Malcolm K. Brenner

Florida Institute of Technology — United States

Medicine · Health Sciences

115h-index53.4kcitations879works17.22yr avg
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Research Topics

CAR-T cell therapy research(446), Virus-based gene therapy research(241), Immune Cell Function and Interaction(198), Immunotherapy and Immune Responses(141), Hematopoietic Stem Cell Transplantation(127)

Publications873 total

CLL-1 chimeric antigen receptor T-cells for the treatment of Acute Myeloid Leukemia: A phase 1 clinical trial
Blood·2025
Interim analysis of safety and efficacy in a Phase 2 study of MB-105, a CD5.CAR T therapy for patients with relapsed/refractory T cell lymphoma
Blood·2025Open Access
MT-601 demonstrates favorable safety and durable responses in relapsed or refractory (r/r) non-Hodgkin lymphoma (NHL)
Blood·2025
553 A phase I clinical trial of allogeneic NKT cells expressing a CD19-specific CAR in patients with relapsed or refractory B cell malignancies: an interim analysis
Regular and Young Investigator Award Abstracts·2025Open Access
Peritoneal Immunosurgery: Immunotherapy Augmented Surgery for the Treatment of Peritoneal Cancers
Journal of Surgical Oncology·2025Open Access
A phase 2 study to confirm safety and efficacy of MB-105, an autologous CD5-directed CAR T-cell therapy, in relapsed/refractory T-cell lymphoma (R/R TCL).
Journal of Clinical Oncology·2025
Reconstruction of 3D vascular flow patterns from sparse angiographic data using a 3D convolutional neural network (CNN)
2025
Long-term outcomes of GD2-directed CAR-T cell therapy in patients with neuroblastoma
Nature Medicine·2025· 36 cited
Interleukin-15-armoured GPC3 CAR T cells for patients with solid cancers
Carolina Digital Repository (University of North Carolina at Chapel Hill)·2024· 6 citedOpen Access
Editorial Expression of Concern: E1A-induced apoptosis does not prevent replication of adenoviruses with deletion of E1b in majority of infected cancer cells
Cancer Gene Therapy·2024Open Access
Interleukin-15-armoured GPC3 CAR T cells for patients with solid cancers
Nature·2024· 155 citedOpen Access
Autologous HER2-specific CAR T cells after lymphodepletion for advanced sarcoma: a phase 1 trial
UNC Libraries·2024· 1 citedOpen Access
294 Banana lectin CAR T cells to target pancreatic cancer
Regular and Young Investigator Award Abstracts·2024Open Access
IL-12 encoding oNDV synergizes with CAR-T cells in orthotopic models of non-small cell lung cancer
Molecular Therapy Oncology·2024· 2 citedOpen Access
Abstract B037: Banana Lectin expressing CAR T cells to target Pancreatic Cancer
Cancer Research·2024
Gemcitabine, carboplatin, and Epstein–Barr virus-specific autologous cytotoxic T lymphocytes for recurrent or metastatic nasopharyngeal carcinoma: VANCE, an international randomized phase III trial
Annals of Oncology·2024· 10 citedOpen Access
Chimeric antigen receptor-induced antigen loss protects CD5.CART cells from fratricide without compromising on-target cytotoxicity
Cell Reports Medicine·2024· 11 citedOpen Access
Mesenchymal stromal cells protect combined oncolytic and helper-dependent adenoviruses from humoral immunity
Molecular Therapy — Methods & Clinical Development·2024Open Access
Binary oncolytic adenovirus in combination with HER2-specific autologous CAR VST for treatment of advanced HER2-positive solid tumors (VISTA).
Journal of Clinical Oncology·2024· 8 cited
Bispecific antibodies and autologous chimeric antigen receptor T cell therapies for treatment of hematological malignancies
Molecular Therapy·2024· 18 citedOpen Access
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Frequent Co-authors

Cliona M. Rooney(38), Helen E. Heslop(37), Gianpietro Dotti(21), Adrian P. Gee(21), Hao Liu(15), Barbara Savoldo(15), Robert A. Krance(13), Bambi Grilley(12), Catherine M. Bollard(12), Zhuyong Mei(9), Carlos A. Ramos(9), Meng-Fen Wu(8), Stephen Gottschalk(8), Enli Liu(7), Martin Pulé(7), M. Helen Huls(7), Ann M. Leen(7), Karin Straathof(6), George Carrum(6), Olga Dakhova(5)