Emily Hopewell

Medicine · Health Sciences

8h-index488citations25works1.42yr avg
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Research Topics

CAR-T cell therapy research(7), NF-κB Signaling Pathways(5), Immune Response and Inflammation(4), Immunotherapy and Immune Responses(4), Immune Cell Function and Interaction(4)

Publications25 total

Advancing Cell Therapies for Solid Tumors: A Pathway to Overcome Biological, Operational, and Regulatory Hurdles
Transplantation and Cellular Therapy·2026
Feasibility and tolerability of a CD4 re-directed chimeric antigen receptor T cell therapy (CD4CAR) in hematologic malignancies: Initial Results from multi-institutional first-in-human trials
Blood·2025Open Access
552 Feasibility and tolerability of a CD4 re-directed chimeric antigen receptor T cell therapy (CD4CAR) in hematological malignancies: Initial results from multi-institutional first-in-human (FIH) trials
Regular and Young Investigator Award Abstracts·2025Open Access
358 Efficient expansion of clinical-grade nature killer cells using the G-rex bioreactor for adoptive immunotherapy trials
Regular and Young Investigator Award Abstracts·2025Open Access
Reprogramming intratumoral T <sub>reg</sub> cells by morpholino-mediated splicing of FOXP3 for cancer immunotherapy
Science Immunology·2025· 2 cited
Analysis of the Suitability of an in vitro Killing Assay to Assess the Function of CD4CAR
Cytotherapy·2025
CAR-T cell therapy for treatment of acute myeloid leukemia, advances and outcomes
Molecular Therapy·2025· 8 cited
Survey of genetic counselors identifies a knowledge gap discerning properly regulated cell and gene therapy trials
Cytotherapy·2023
Process Development and Manufacturing: FEASIBILITY OF LENTIVIRAL VECTOR PRODUCTION USING A NOVEL AIRLIFT BIOREACTOR
Cytotherapy·2023
A novel computer-based system to develop cell therapy protocols: digitizing manufacturing processes without specialized information technology expertise
Cytotherapy·2021
Vector production in academia: obstacles and opportunities
Cell and Gene Therapy Insights·2020Open Access
Vector production in academia: obstacles and opportunities
Publisher·2020
Manufacturing Dendritic Cells for Immunotherapy: Monocyte Enrichment
Molecular Therapy — Methods & Clinical Development·2020· 40 citedOpen Access
Manufacturing Dendritic Cells for Immunotherapy: Monocyte Enrichment
PMC·2020
Tumor-infiltrating lymphocytes: Streamlining a complex manufacturing process
Cytotherapy·2018· 58 cited
A phase I/randomized phase II study of GM.CD40L vaccine in combination with CCL21 in patients with advanced lung adenocarcinoma
Cancer Immunology Immunotherapy·2018· 34 citedOpen Access
A Clinical Grade Cell Based Artificial APC, APC/aCD3/aCD28/Hbd, for High Quality hCD19 CAR-T Expansion and Gene Transduction
Biology of Blood and Marrow Transplantation·2018Open Access
NF‐κB is crucial in proximal T‐cell signaling for calcium influx and NFAT activation
European Journal of Immunology·2014· 12 citedOpen Access
Differential Requirement for the IKKβ/NF-κB Signaling Module in Regulating TLR- versus RLR-Induced Type 1 IFN Expression in Dendritic Cells
The Journal of Immunology·2014· 19 citedOpen Access
Lung tumor NF-κB signaling promotes T cell–mediated immune surveillance
Journal of Clinical Investigation·2013· 103 cited
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Frequent Co-authors

Amer A. Beg(7), Crystina C. Bronk(5), Junmei Wang(4), Esteban Celis(4), Robert W. Engelman(3), Xue‐Zhong Yu(3), Cheryl A. Cox(3), Linda Kelley(3), Huda Salman(3), Mateusz Opyrchal(3), Amer Beitinjaneh(3), Lionel Apétoh(3), Daniela Bischof(3), Xingyu Wang(2), Randy A. Albrecht(2), Adolfo Garcı́a-Sastre(2), Siddharth Balachandran(2), Michael T. Massengill(2), Scott Antonia(2), Eric B. Haura(2)