Sérgio Lilla

Cancer Research UK — United Kingdom

Medicine · Health Sciences

28h-index3.4kcitations166works6.72yr avg
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Research Topics

Prostate Cancer Treatment and Research(24), PARP inhibition in cancer therapy(14), Mass Spectrometry Techniques and Applications(13), Cancer, Hypoxia, and Metabolism(12), Cellular Mechanics and Interactions(11)

Publications166 total

Structural and functional analysis of the TGF-β mimic, TGM-2: an immunomodulatory helminth protein
Genes and Immunity·2025Open Access
Nucleophosmin supports WNT-driven hyperproliferation and tumor initiation
Nature Genetics·2025Open Access
CYRI-B loss promotes enlarged mature focal adhesions and restricts microtubule and ERC1 access to the cell leading edge
Journal of Cell Science·2025· 1 citedOpen Access
Macrophage chemotaxis steered by complex self-generated gradients of complement C5a
2025Open Access
Functionally dominant hotspot mutations of mitochondrial ribosomal RNA genes in cancer
Nature Genetics·2025· 3 citedOpen Access
SICyLIA-cTMT dissects redox proteome dynamics with high accuracy and depth at microgram scale
Cell Reports Methods·2025Open Access
SLC25A45 is required for mitochondrial uptake of methylated amino acids and de novo carnitine biosynthesis
Molecular Cell·2025· 5 citedOpen Access
The AMPK-related kinase NUAK1 regulates neuronal morphogenesis through the RNA splicing co-factor SON
2025Open Access
The PP2A-B55α phosphatase is a master regulator of mitochondrial degradation and biogenesis
Science Advances·2025· 1 citedOpen Access
P3.14.08 Genetically Defined Mouse Models of Malignant Pleural Mesothelioma Recapitulate Human MPM Phenotypes and Response to Therapy
Journal of Thoracic Oncology·2025
A proliferation associated tRNA regulatory nexus on human chromosome 6 plays a central role in cell state-dependent gene expression
2025· 1 citedOpen Access
Radiotherapy drives lung metastasis in PDAC via a RhoGTPase signaling shift towards MRCK-dependency
2025Open Access
Abstract 027: Vascular Smooth Muscle Cell Plasticity in Human Hypertension Is Defined by a Distinct Oxidative Proteome and Downregulation of Nox5-Targeting miRNAs
Hypertension·2025
Overcoming Preservation Challenges to Enable Single-Cell Proteomics of Fixed Cells and Tissue Samples with Retained Proteome Integrity
Journal of Proteome Research·2025· 1 citedOpen Access
Locking CBL TKBD in its native conformation presents a novel therapeutic opportunity in mutant CBL-dependent leukemia
Molecular Therapy·2025· 1 citedOpen Access
Overcoming preservation challenges to enable single-cell proteomics of fixed cell and tissue samples with retained proteome integrity
2025Open Access
Engineered Immunomodulatory Extracellular Vesicles from Epithelial Cells with the Capacity for Stimulation of Innate and Adaptive Immunity in Cancer and Autoimmunity
ACS Nano·2025· 5 citedOpen Access
The TGF-β mimic TGM4 achieves cell specificity through combinatorial surface co-receptor binding
EMBO Reports·2024· 8 citedOpen Access
Scar/WAVE drives actin protrusions independently of its VCA domain using proline-rich domains
Current Biology·2024· 9 citedOpen Access
Biogenesis of lysosome-related organelles complex-2 is an evolutionarily ancient proto-coatomer complex
Current Biology·2024· 6 citedOpen Access
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Frequent Co-authors

Sara Zanivan(24), David Sumpton(9), Gilberto De Nucci(9), Karen Blyth(8), Colin Nixon(6), Giovanny Rodriguez Blanco(5), Gillian Mackay(5), Hing Y. Leung(5), Lisa J. Neilson(5), Massimiliano Mazzone(5), Laura M. Machesky(5), Peter A. Thomason(5), Robert H. Insall(5), Francesco Addeo(5), Rachana Patel(4), Chara Ntala(4), Mark J. Salji(4), Elke Markert(4), Shehab Ismail(4), Jim C. Norman(4)