Alexandra Beilina

National Institutes of Health — United States

Medicine · Health Sciences

40h-index6.0kcitations86works1.42yr avg
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Research Topics

Parkinson's Disease Mechanisms and Treatments(42), Cellular transport and secretion(20), Lysosomal Storage Disorders Research(11), Plant Gene Expression Analysis(9), Autophagy in Disease and Therapy(7)

Publications86 total

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Zenodo (CERN European Organization for Nuclear Research)·2026Open Access
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Zenodo (CERN European Organization for Nuclear Research)·2026Open Access
asap-raw-team-indipd-ipsc-lr-wgs-kolf21j-wt
Zenodo (CERN European Organization for Nuclear Research)·2026Open Access
team-indipd-ipsc-bulk-rnaseq-kolf21j-wt
Zenodo (CERN European Organization for Nuclear Research)·2026Open Access
asap-raw-team-indipd-ipsc-cageseq-kolf21j-wt
Zenodo (CERN European Organization for Nuclear Research)·2026Open Access
asap-raw-team-indipd-ipsc-cageseq-kolf21j-wt
Zenodo (CERN European Organization for Nuclear Research)·2026Open Access
Inflammatory signaling differentially changes chromatin accessibility and gene expression of the PD- associated kinase LRRK2 between human and mice
2026Open Access
14-3-3 binding maintains the Parkinson’s associated kinase LRRK2 in an inactive state
Nature Communications·2025· 7 citedOpen Access
JIP4 and RILPL1 utilize opposing motor force to dynamically regulate lysosomal tubulation
The Journal of Cell Biology·2025Open Access
Triglyceride metabolism controls inflammation and microglial phenotypes associated with APOE4
Cell Reports·2025· 8 citedOpen Access
Regulation of LRRK2 activity by metabolic stress and heavy metal exposure
Brain Research·2025Open Access
Large-scale HLA immunopeptidome and interactome profiling in microglia
2025Open Access
Large-Scale HLA Immunopeptidome and Interactome Profiling in Microglia
SSRN Electronic Journal·2025Open Access
Characterization of DNA methylation in PBMCs and donor-matched iPSCs shows methylation is reset during stem cell reprogramming
2024Open Access
14-3-3 binding maintains the Parkinson’s associated kinase LRRK2 in an inactive state
2024· 3 citedOpen Access
Opposing actions of JIP4 and RILPL1 provide antagonistic motor force to dynamically regulate membrane reformation during lysosomal tubulation/sorting driven by LRRK2
2024· 5 citedOpen Access
The Foundational Data Initiative for Parkinson Disease: Enabling efficient translation from genetic maps to mechanism
Cell Genomics·2023· 46 citedOpen Access
Lysosomal positioning regulates Rab10 phosphorylation at LRRK2 <sup>+</sup> lysosomes
Proceedings of the National Academy of Sciences·2022· 51 citedOpen Access
Association of a common genetic variant with Parkinson’s disease is mediated by microglia
Science Translational Medicine·2022· 88 citedOpen Access
Mutations in LRRK2 linked to Parkinson disease sequester Rab8a to damaged lysosomes and regulate transferrin-mediated iron uptake in microglia
PLoS Biology·2021· 80 citedOpen Access
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Frequent Co-authors

Mark Cookson(41), Elisa Greggio(11), Ravindran Kumaran(10), Patrick A. Lewis(9), Adamantios Mamais(9), Alice Kaganovich(8), Andrew Singleton(8), Jean‐Marc Taymans(8), Veerle Baekelandt(7), Rili Ahmad(6), Luis Bonet‐Ponce(6), Yan Li(6), J. Raphael Gibbs(6), Kelly Jean Thomas Craig(5), David W. Miller(5), Kirsten Harvey(5), Jillian H. Kluss(5), Xylena Reed(5), Rina Bandopadhyay(4), Jeff Blackinton(4)