Grishma Pawar

University Health Network — Canada

Biochemistry, Genetics and Molecular Biology · Life Sciences

8h-index312citations11works4.02yr avg
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Research Topics

RNA Interference and Gene Delivery(5), Parkinson's Disease Mechanisms and Treatments(4), Nerve injury and regeneration(3), Advanced Drug Delivery Systems(3), Neurogenesis and neuroplasticity mechanisms(2)

Publications11 total

Reduction of alpha-synuclein oligomers in preclinical models of Parkinson’s disease by electrical stimulation in vitro and deep brain stimulation in vivo
Brain stimulation·2024· 4 citedOpen Access
Disrupting the α-synuclein-ESCRT interaction with a peptide inhibitor mitigates neurodegeneration in preclinical models of Parkinson’s disease
Nature Communications·2023· 45 citedOpen Access
Small molecule inhibitors of α-synuclein oligomers identified by targeting early dopamine-mediated motor impairment in C. elegans
Molecular Neurodegeneration·2021· 26 citedOpen Access
Endonasal CNS Delivery System for Blood-Brain Barrier Impermeant Therapeutic Oligonucleotides Using Heterotopic Mucosal Engrafting
Frontiers in Pharmacology·2021· 14 citedOpen Access
Minimally Invasive Nasal Depot (MIND) technique for direct BDNF AntagoNAT delivery to the brain
Journal of Controlled Release·2021· 63 citedOpen Access
LRRK2 and α-Synuclein: Distinct or Synergistic Players in Parkinson’s Disease?
Frontiers in Neuroscience·2020· 74 citedOpen Access
Trans-nasal mucosal delivery of BDNF antagoNAT oligonucleotides using heterotopic mucosal engrafting for Parkinson's disease
2019· 2 citedOpen Access
CNS Delivery and Anti-Inflammatory Effects of Intranasally Administered Cyclosporine-A in Cationic Nanoformulations
Journal of Pharmacology and Experimental Therapeutics·2018· 22 citedOpen Access
Direct CNS delivery of proteins using thermosensitive liposome-in-gel carrier by heterotopic mucosal engrafting
PLoS ONE·2018· 22 citedOpen Access
Neurodegenerative Disease
2017· 3 cited
MicroRNA-34a Encapsulated in Hyaluronic Acid Nanoparticles Induces Epigenetic Changes with Altered Mitochondrial Bioenergetics and Apoptosis in Non-Small-Cell Lung Cancer Cells
Scientific Reports·2017· 37 citedOpen Access

Frequent Co-authors

Mansoor M. Amiji(6), Suneil K. Kalia(4), Lorraine V. Kalia(4), Benjamin S. Bleier(4), Darren M. O’Hara(3), Minesh Kapadia(3), Neha N. Parayath(3), Olga Khorkova(2), Jane Hsiao(2), Kazuko Fujisawa(2), Hien Chau(2), Omar M. A. El‐Agnaf(2), Andrés M. Lozano(2), Smrithi Padmakumar(1), Gregory Jones(1), Jonghan Kim(1), Satra Nim(1), Carles Corbi‐Verge(1), Albert Perez‐Riba(1), Federica Albanese(1)