Józef Oleksyszyn

Wrocław University of Science and Technology — Poland

Chemistry · Physical Sciences

26h-index2.2kcitations104works0.02yr avg
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Research Topics

Organophosphorus compounds synthesis(30), Peptidase Inhibition and Analysis(21), Protease and Inhibitor Mechanisms(16), Chemical Synthesis and Analysis(14), Synthesis and Reactivity of Sulfur-Containing Compounds(14)

Publications104 total

Diisothiocyanate-Derived Mercapturic Acids Are a Promising Partner for Combination Therapies in Glioblastoma
ACS Omega·2022Open Access
Cover Picture: Phosphonic Analogs of Alanine as Acylpeptide Hydrolase Inhibitors (Chem. Biodiversity 2/2021)
Chemistry & Biodiversity·2021
Phosphonic Analogs of Alanine as Acylpeptide Hydrolase Inhibitors
Chemistry & Biodiversity·2021· 2 cited
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Anti-Cancer Agents in Medicinal Chemistry·2020Open Access
Structure-based design, synthesis, and evaluation of the biological activity of novel phosphoroorganic small molecule IAP antagonists
Investigational New Drugs·2020· 6 citedOpen Access
3,4-dimethoxybenzyl isothiocyanate enhances doxorubicin efficacy in LoVoDX doxorubicin-resistant colon cancer and attenuates its toxicity in vivo
Life Sciences·2019· 12 cited
Development and Evaluation of an Immunoglobulin Y-Based ELISA for Measuring Prostate Specific Antigen in Human Serum
Annals of Laboratory Medicine·2019· 26 citedOpen Access
Phosphonate inhibitors of West Nile virus NS2B/NS3 protease
Journal of Enzyme Inhibition and Medicinal Chemistry·2018· 26 citedOpen Access
Viability of glioblastoma stem cells is effectively reduced by diisothiocyanate‑derived mercapturic acids
Oncology Letters·2018· 4 citedOpen Access
Phosphorus-containing isothiocyanate-derived mercapturic acids as a useful alternative for parental isothiocyanates in experimental oncology
Bioorganic & Medicinal Chemistry Letters·2018· 3 cited
Design, Synthesis, and Evaluation of ω‐(Isothiocyanato)alkylphosphinates and Phosphine Oxides as Antiproliferative Agents
ChemMedChem·2017· 12 cited
Development of Adenosine Deaminase-Specific IgY Antibodies: Diagnostic and Inhibitory Application
Applied Biochemistry and Biotechnology·2017· 13 citedOpen Access
Novel peptidyl α-aminoalkylphosphonates as inhibitors of hepatitis C virus NS3/4A protease
Antiviral Research·2017· 7 citedOpen Access
Novel phosphonate analogs of sulforaphane: Synthesis, in vitro and in vivo anticancer activity
European Journal of Medicinal Chemistry·2017· 32 cited
Peptidyl derivatives of diaryl 1-aminoalkylphosphonates as a new potential antibacterial and antiviral agent
Organic Chemistry Current Research·2017
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Anti-Cancer Agents in Medicinal Chemistry·2017
Development of novel inhibitors targeting NS3/4A protease of hepatitis C virus
Journal of Antivirals & Antiretrovirals·2017
Is It Possible To Induce The "Spontaneous Regression" Of Cancer? A Mechanism of Activation for the Innate Immune Response
Journal of Nutritional Biology·2016· 2 citedOpen Access
Spontaneous Regression of Cancer, an Ever Actual Inspiration for the New Cancer Treatment
Cell Biology Research & Therapy·2016· 3 cited
Targeting viral serine proteases with phosphonic inhibitors
Journal of Antivirals & Antiretrovirals·2015
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Frequent Co-authors

Marcin Sieńczyk(18), Renata Grzywa(10), James C. Powers(8), Marcin Drąg(6), Mateusz Psurski(6), Joanna Wietrzyk(5), Tadeusz Gajda(4), Agnieszka Łupicka‐Słowik(4), Maciej Walczak(4), Przemysław Mastalerz(3), Chih-Min Kam(3), Łukasz Winiarski(3), Anna Gajda(3), Marcin Skoreński(3), Ewa Burchacka(3), Kamila Bobrek(3), Lidia Subotkowska(2), Joe Selzler(2), Bogdan Boduszek(2), Paweł Surowiak(2)