Luke Tweedy

Biochemistry, Genetics and Molecular Biology · Life Sciences

11h-index815citations32works1.62yr avg
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Research Topics

Cellular Mechanics and Interactions(19), 3D Printing in Biomedical Research(8), Cell Image Analysis Techniques(6), Microtubule and mitosis dynamics(3), Advanced Fluorescence Microscopy Techniques(3)

Publications32 total

Dataset for: Macrophage chemotaxis steered by complex self-generated gradients of complement C5a
University College London·2026Open Access
Dataset for: Macrophage chemotaxis steered by complex self-generated gradients of complement C5a
University College London·2026Open Access
CYRI-B loss promotes enlarged mature focal adhesions and restricts microtubule and ERC1 access to the cell leading edge
Journal of Cell Science·2025· 1 citedOpen Access
Macrophage chemotaxis steered by complex self-generated gradients of complement C5a
2025Open Access
Scar/WAVE drives actin protrusions independently of its VCA domain using proline-rich domains
Current Biology·2024· 9 citedOpen Access
A Reliable System for Quantitative G-Protein Activation Imaging in Cancer Cells
Cells·2024· 1 citedOpen Access
CYRI-B loss promotes enlarged mature focal adhesions and restricts microtubule and ERC1 access to the cell leading edge
2024Open Access
How Should Eukaryotic Chemotaxis be Measured?
2023Open Access
Competition between chemoattractants causes unexpected complexity and can explain negative chemotaxis
Current Biology·2023· 19 citedOpen Access
Competition between chemoattractants causes unexpected complexity and can explain negative chemotaxis
2022· 1 citedOpen Access
AKT and SGK kinases regulate cell migration by altering Scar/WAVE complex activation and Arp2/3 complex recruitment
Frontiers in Molecular Biosciences·2022· 5 citedOpen Access
The Scar/WAVE complex drives normal actin protrusions without the Arp2/3 complex, but proline-rich domains are required
2022· 5 citedOpen Access
Steering yourself by the bootstraps: how cells create their own gradients for chemotaxis
Trends in Cell Biology·2022· 38 citedOpen Access
Competition Between Chemoattractants Causes Unexpected Complexity and Can Explain Negative Chemotaxis
SSRN Electronic Journal·2022Open Access
Seeing around corners: Cells solve mazes and respond at a distance using attractant breakdown
Science·2020· 158 citedOpen Access
Self-Generated Gradients Yield Exceptionally Robust Steering Cues
Frontiers in Cell and Developmental Biology·2020· 49 citedOpen Access
Seeing around corners: Cells create chemotactic gradients to solve mazes and respond to distant cues in complex environments
2019· 2 citedOpen Access
Screening by changes in stereotypical behavior during cell motility
Scientific Reports·2019· 10 citedOpen Access
Screening by changes in stereotypical behavior during cell motility
arXiv (Cornell University)·2019Open Access
The Atypical MAP Kinase ErkB Transmits Distinct Chemotactic Signals through a Core Signaling Module
Developmental Cell·2019· 38 citedOpen Access
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Frequent Co-authors

Robert H. Insall(25), Peter A. Thomason(15), Peggy Paschke(13), Laura M. Machesky(7), Jamie Whitelaw(5), Sérgio Lilla(5), Doris Heinrich(5), Robert G. Endres(5), Nikki R. Paul(4), Kirsty J. Martin(3), Gillian Mackay(3), Loïc Fort(3), Sara Zanivan(3), Olivia Susanto(3), Adam Dowdell(3), Shashi Prakash Singh(3), David M Versluis(3), Isabel Bravo-Ferrer(3), Amy L. Shergold(3), Michele Zagnoni(2)