Brett Lovejoy

Biochemistry, Genetics and Molecular Biology · Life Sciences

11h-index2.0kcitations20works0.02yr avg
OpenAlex↗Google Scholar↗

Accepting Students?

No reports yet. Know if this professor is taking students?

Research Topics

Protease and Inhibitor Mechanisms(4), Protein Structure and Dynamics(3), Cancer-related Molecular Pathways(3), Chemical Synthesis and Analysis(3), Peptidase Inhibition and Analysis(3)

Publications20 total

P38 kinase crystal structure in complex with 3-(2,6-Dichloro-phenyl)-7-[4-(2-diethylamino-ethoxy)-phenylamino]-1-methyl-3,4-dihydro-1H-pyrimido[4,5-d]pyrimidin-2-one
2009
Design and Synthesis of 4-Azaindoles as Inhibitors of p38 MAP Kinase
Journal of Medicinal Chemistry·2003· 94 citedOpen Access
Retraction
Science·2002· 8 cited
Oxindole-Based Inhibitors of Cyclin-Dependent Kinase 2 (CDK2):  Design, Synthesis, Enzymatic Activities, and X-ray Crystallographic Analysis
Journal of Medicinal Chemistry·2001· 267 citedOpen Access
Prevention of Chemotherapy-Induced Alopecia in Rats by CDK Inhibitors
Science·2001· 167 cited
THE STRUCTURE OF CDK2/CYCLIN A IN COMPLEX WITH AN OXINDOLE INHIBITOR
2000
THE STRUCTURE OF CYCLIN-DEPENDENT KINASE 2 (CDK2) IN COMPLEX WITH AN OXINDOLE INHIBITOR
2000
Crystal structures of MMP-1 and -13 reveal the structural basis for selectivity of collagenase inhibitors.
Nature Structural Biology·1999· 248 cited
CRYSTAL STRUCTURE OF FIBROBLAST COLLAGENASE-1 COMPLEXED TO A DIPHENYL-ETHER SULPHONE BASED HYDROXAMIC ACID
1998
CRYSTAL STRUCTURE OF COLLAGENASE-3 (MMP-13) COMPLEXED TO A DIPHENYL-ETHER SULPHONE BASED HYDROXAMIC ACID
1998
Crystal Structure of the Catalytic Domain of the Human Cell Cycle Control Phosphatase, Cdc25A
Cell·1998· 282 citedOpen Access
HUMAN CDC25A CATALYTIC DOMAIN
1998
Crystallization of a designed peptide from a molten globule ensemble
Folding and Design·1996· 28 cited
Structural Analysis of the Catalytic Domain of Human Fibroblast Collagenase
Annals of the New York Academy of Sciences·1994· 18 cited
Crystal Structures of Recombinant 19-kDa Human Fibroblast Collagenase Complexed to Itself
Biochemistry·1994· 157 cited
Structure of the Catalytic Domain of Fibroblast Collagenase Complexed with an Inhibitor
Science·1994· 331 cited
Crystal Structure of Canine and Bovine Granulocyte-Colony Stimulating Factor (G-CSF)
Journal of Molecular Biology·1993· 54 cited
Crystal Structure of a Synthetic Triple-Stranded α-Helical Bundle
Science·1993· 287 cited
Crystallization of proton channel peptides
Protein Science·1992· 9 citedOpen Access
X‐ray grade crystals of a designed <i>α</i>‐helical coiled coil
Protein Science·1992· 11 citedOpen Access

Frequent Co-authors

Anne M. Hassell(8), Warren J. Rocque(7), William D. Holmes(7), David Eisenberg(5), H. Neal Bramson(5), Stephen T. Davis(5), Stephen V. Frye(5), Robert T. Gampe(5), Philip A. Harris(5), R. Hunter(5), Karen Lackey(5), Michael J. Luzzio(5), James M. Veal(5), William F. DeGrado(4), Lisa M. Shewchuk(4), Michelle F. Browner(4), Bill Benson(4), Karen M. Dold(4), Derek J. Eberwein(4), Robert Griffin(4)