Felix Hausch

Darmstadt University of Applied Sciences — Germany

Biochemistry, Genetics and Molecular Biology · Life Sciences

41h-index7.1kcitations237works4.22yr avg
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Research Topics

Signaling Pathways in Disease(91), Heat shock proteins research(35), Stress Responses and Cortisol(33), Receptor Mechanisms and Signaling(31), Endoplasmic Reticulum Stress and Disease(20)

Publications237 total

Pharmacological Inhibition of FKBP51 Mitigates Early Life Adversity-Induced Social Deficits
2025Open Access
Targeting bacterial kinases as a strategy to counteract antibiotic resistance
Communications Chemistry·2025· 1 citedOpen Access
Fragment-based drug design of a bacterial kinase inhibitor capable of increasing the antibiotic sensitivity of clinical isolates
Communications Chemistry·2025· 1 citedOpen Access
Linker Modification Enables Control of Key Functional Group Orientation in Macrocycles
Journal of Medicinal Chemistry·2025
Analgesia through FKBP51 inhibition at disease onset confers lasting relief from sensory and emotional chronic pain symptoms
Proceedings of the National Academy of Sciences·2025· 1 citedOpen Access
Stress, epigenetic remodeling and FKBP51: Pathways to chronic pain vulnerability
Brain Behavior and Immunity·2025Open Access
A new FKBP51-GR-p23-Hsp90 <sub>2</sub> multi-cochaperone complex identified and characterized by site-specific in-cell photocrosslinking
2025
Heterobifunctional Protein Binders Enable Cell Type-Specific Killing Through In-cell Enrichment
2025· 1 citedOpen Access
Broad Target Screening Reveals Abundance of FKBP12-Based Molecular Glues in Focused Libraries
Journal of Medicinal Chemistry·2025· 6 cited
Novel PROTAC to target FKBP12: the potential to enhance bone morphogenetic protein activity and apoptosis in multiple myeloma
Haematologica·2025· 3 citedOpen Access
Nondegradative Synthetic Molecular Glues Enter the Clinic
ChemMedChem·2025· 5 citedOpen Access
Exploring the potential of selective FKBP51 inhibitors on melanoma: an investigation of their in vitro and in vivo effects
Cell Death Discovery·2025· 2 citedOpen Access
Further Support for FKBP51 as a Therapeutic Target for Chronic Posttraumatic Pain
Journal of Pain·2025
Identification and characterization of potent and selective inhibitors for the B <sup>0</sup> AT2/SLC6A15 amino acid transporter
2025Open Access
Frontispiz: Konformationsplastizität und Steigerung der Bindungsaffinität durch Linker‐Derivatisierung in Makrozyklen
Angewandte Chemie·2025Open Access
Frontispiece: Conformational Plasticity and Binding Affinity Enhancement Controlled by Linker Derivatization in Macrocycles
Angewandte Chemie International Edition·2025Open Access
GlnA3 <i> <sub>Mt</sub> </i> is able to glutamylate spermine but it is not essential for the detoxification of spermine in <i>Mycobacterium tuberculosis</i>
Journal of Bacteriology·2025· 4 citedOpen Access
Macrocyclization as a Strategy for Kinetic Solubility Improvement: A Comparative Analysis of Matched Molecular Pairs
Journal of Medicinal Chemistry·2025· 4 cited
Stress, Epigenetic Remodeling and FKBP51: Pathways to Chronic Pain Vulnerability
2025· 1 cited
Konformationsplastizität und Steigerung der Bindungsaffinität durch Linker‐Derivatisierung in Makrozyklen
Angewandte Chemie·2025Open Access
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Frequent Co-authors

C. Kozany(16), Andreas Bracher(12), Mathias V. Schmidt(11), Theo Rein(7), Jakob Hartmann(7), Herta Flor(7), Xixi Feng(6), Nils C. Gassen(5), Ulrike Schmidt(5), S. Gaali(5), Claudia Sippel(5), Marcelo Páez-Pereda(5), Alexander Kirschner(4), Max L. Pöhlmann(4), A. Fabian(4), Andreas Hähle(4), R. Gopalakrishnan(4), Chaitan Khosla(3), Kathrin Hafner(3), Chadi Touma(3)