Dirk Finsinger

Merck (Germany) — Germany

Medicine · Health Sciences

14h-index1.4kcitations23works5.02yr avg
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Research Topics

Cell Adhesion Molecules Research(8), Monoclonal and Polyclonal Antibodies Research(6), Computational Drug Discovery Methods(4), Chemical Synthesis and Analysis(3), Click Chemistry and Applications(3)

Publications23 total

The European Lead Factory: Results from a decade of collaborative, public–private, drug discovery programs
Drug Discovery Today·2024· 5 citedOpen Access
IMI European Lead Factory — democratizing access to high-throughput screening
Nature Reviews Drug Discovery·2021· 4 citedOpen Access
The European Federation for Medicinal Chemistry and Chemical Biology (EFMC) Best Practice Initiative: Phenotypic Drug Discovery
ChemMedChem·2021· 14 cited
The European Federation for Medicinal Chemistry (EFMC) Best Practice Initiative: Validating Chemical Probes
ChemMedChem·2020· 14 citedOpen Access
Discovery of novel 7-azaindoles as PDK1 inhibitors
Bioorganic & Medicinal Chemistry Letters·2016· 19 citedOpen Access
Fluctuating Open Teams (FLOT) – A New Approach to Boost Team Creativity and Innovation Potential
Technology Transfer and Entrepreneurship·2014· 1 cited
Design and synthesis of isoquinolines and benzimidazoles as RAF kinase inhibitors
Bioorganic & Medicinal Chemistry Letters·2011· 20 citedOpen Access
The discovery and optimization of hexahydro-2H-pyrano[3,2-c]quinolines (HHPQs) as potent and selective inhibitors of the mitotic kinesin-5
Bioorganic & Medicinal Chemistry Letters·2010· 63 citedOpen Access
Cyclopropyl Building Blocks in Organic Synthesis. Part 124. Access to Variously Substituted 5,6,7,8‐Tetrahydro‐3H‐quinazolin‐4‐ones via Diels—Alder Adducts of Phenyl Vinyl Sulfone to Cyclobutene‐Anellated Pyrimidinones.
ChemInform·2006
Discovery, synthesis and characterization of hexahydropyranoquinolines as a novel class of selective inhibitors of the mitotic kinesin Eg5.
Cancer Research·2006
Access to Variously Substituted 5,6,7,8‐Tetrahydro‐3<i>H</i>‐quinazolin‐4‐ones via Diels–Alder Adducts of Phenyl Vinyl Sulfone to Cyclobutene‐Annelated Pyrimidinones
European Journal of Organic Chemistry·2006· 29 cited
Recent progress in the field of αv-integrin antagonists
2002
Intervesicle Cross-Linking with Integrin α<sub>IIb</sub>β<sub>3</sub>and Cyclic-RGD-Lipopeptide. A Model of Cell-Adhesion Processes
Biochemistry·2000· 47 cited
Surface Coating with Cyclic RGD Peptides Stimulates Osteoblast Adhesion and Proliferation as well as Bone Formation
ChemBioChem·2000· 17 cited
Surface Coating with Cyclic RGD Peptides Stimulates Osteoblast Adhesion and Proliferation as well as Bone Formation
ChemBioChem·2000· 312 cited
Protective copolymers for nonviral gene vectors: synthesis, vector characterization and application in gene delivery
Gene Therapy·2000· 147 cited
Selektive RGD-vermittelte Adhäsion von Osteoblasten an Implantat-Oberflächen
Angewandte Chemie·1999· 30 cited
Selective RGD-Mediated Adhesion of Osteoblasts at Surfaces of Implants
Angewandte Chemie International Edition·1999· 119 cited
Selektive RGD-vermittelte Adhäsion von Osteoblasten an Implantat-Oberflächen
Angewandte Chemie·1999· 2 cited
ChemInform Abstract: Stereoisomeric Peptide Libraries and Peptidomimetics for Designing Selective Inhibitors of αvβ3 Integrin for a New Cancer Therapy
ChemInform·1997
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Frequent Co-authors

Horst Kessler(11), Alfred Jonczyk(7), Martin Kantlehner(6), Patricia Schaffner(6), Beate Diefenbach(6), J. Meyer(5), Berthold Nies(5), Roland Haubner(4), Günter Hölzemann(4), Simon L. Goodman(4), Frank T. Zenke(3), Christiane Amendt(3), Thorsten Knöchel(3), Hans‐Peter Buchstaller(3), Kai Schiemann(2), David Bruge(2), Ulrich Emde(2), Jochen Wermuth(2), Suryakanta Dalai(2), Vladimir N. Belov(2)