Ulrich Emde

Merck (Germany) — Germany

Biochemistry, Genetics and Molecular Biology · Life Sciences

10h-index433citations19works0.02yr avg
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Research Topics

Traditional and Medicinal Uses of Annonaceae(10), Cocoa and Sweet Potato Agronomy(9), Synthetic Organic Chemistry Methods(6), Asymmetric Synthesis and Catalysis(4), Carbohydrate Chemistry and Synthesis(3)

Publications19 total

Abstract 4198: Highly potent and selective DNA-PK inhibitor M3814 with sustainable anti-tumor activity in combination with radiotherapy
Cancer Research·2017· 6 cited
The discovery and optimization of hexahydro-2H-pyrano[3,2-c]quinolines (HHPQs) as potent and selective inhibitors of the mitotic kinesin-5
Bioorganic & Medicinal Chemistry Letters·2010· 63 citedOpen Access
Discovery, synthesis and characterization of hexahydropyranoquinolines as a novel class of selective inhibitors of the mitotic kinesin Eg5.
Cancer Research·2006
Studies of stereocontrolled allylation reactions for the total synthesis of phorboxazole A
Proceedings of the National Academy of Sciences·2004· 50 citedOpen Access
Total Synthesis of Phorboxazole A.
ChemInform·2003· 2 cited
Total Synthesis of Phorboxazole A
Angewandte Chemie International Edition·2003· 96 cited
Total Synthesis of Phorboxazole A
Angewandte Chemie·2003· 19 cited
ChemInform Abstract: Quinone—Annonaceous Acetogenins: Synthesis and Complex I Inhibition Studies of a New Class of Natural Product Hybrids.
ChemInform·2002
Quinone-Annonaceous Acetogenins: Synthesis and Complex I Inhibition Studies of a New Class of Natural Product Hybrids
Chemistry - A European Journal·2001· 38 cited
Quinone–Annonaceous Acetogenins: Synthesis and Complex I Inhibition Studies of a New Class of Natural Product Hybrids
Chemistry - A European Journal·2001· 1 cited
ChemInform Abstract: Total Syntheses of Squamocin A and Squamocin D, Bi‐tetrahydrofuran Acetogenins from Annonaceae.
ChemInform·2001
ChemInform Abstract: Synthetic Studies Toward Phorboxazole A. Stereoselective Synthesis of the C<sub>28</sub>—C<sub>46</sub> Side Chain Fragment.
ChemInform·2001
Synthetic Studies toward Phorboxazole A. Stereoselective Synthesis of the C<sub>28</sub>−C<sub>46</sub> Side Chain Fragment
Organic Letters·2000· 50 cited
Natural-Product Hybrids: Design, Synthesis, and Biological Evaluation of Quinone-Annonaceous Acetogenins
Angewandte Chemie International Edition·2000· 43 cited
Hybridnaturstoffe: Design, Synthese und biologische Untersuchung von Chinon-Annonin-Acetogeninen
Angewandte Chemie·2000· 11 cited
Total Syntheses of Squamocin A and Squamocin D, Bi-tetrahydrofuran Acetogenins from Annonaceae
European Journal of Organic Chemistry·2000
Total Syntheses of Squamocin A and Squamocin D, Bi-tetrahydrofuran Acetogenins from Annonaceae
European Journal of Organic Chemistry·2000· 33 cited
ChemInform Abstract: Total Syntheses of Squamocin A and Squamocin D.
ChemInform·1999
Total syntheses of squamocin A and squamocin D
Tetrahedron Letters·1999· 21 cited

Frequent Co-authors

Ulrich Koert(10), David R. Williams(6), Michael P. Clark(6), Martin A. Berliner(6), Thorsten Friedrich(5), Lutz Grubert(5), Andre A. Kiryanov(4), Jonathan T. Reeves(4), Frank T. Zenke(3), Sabine Arndt(3), Kai Schiemann(2), Dirk Finsinger(2), Christiane Amendt(2), Thorsten Knöchel(2), Sabine Hoppen(2), Stefan Bäurle(2), David Bruge(1), Hans‐Peter Buchstaller(1), Wolfgang K. Stähle(1), Soheila Anzali(1)