Brian Lin

Fujian Medical University — China

Biochemistry, Genetics and Molecular Biology · Life Sciences

13h-index500citations28works1.42yr avg
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Research Topics

RNA and protein synthesis mechanisms(8), CRISPR and Genetic Engineering(4), Monoclonal and Polyclonal Antibodies Research(4), RNA modifications and cancer(4), Viral Infectious Diseases and Gene Expression in Insects(3)

Publications28 total

Uncovering position-specific patterns in codon and codon-pair usage in candidate genes associated with blood coagulation diseases
NAR Genomics and Bioinformatics·2025Open Access
Cervical cancer molecular subtype identification and prognosis classification by a metabolism-related gene expression
Translational Cancer Research·2025Open Access
A CMOS-Compatible 12nm 8Mb MLC RRAM Enabling Producible 2-Bit Per Cell for High Energy Efficiency Compute-In-Memory in Edge AI Applications
2025· 1 cited
Uncovering codon usage patterns during murine embryogenesis and tissue-specific developmental diseases
Frontiers in Genetics·2025Open Access
Therapeutic implications of synonymous gene recoding: insights into mechanisms controlling protein biogenesis and activity
Protein & Cell·2025Open Access
Abstract 4120: A systematic design of multiplex methylation-specific qPCR for CRC biomarkers
Cancer Research·2025
Mouse embryo CoCoPUTs: novel murine transcriptomic-weighted usage website featuring multiple strains, tissues, and stages
BMC Bioinformatics·2024· 1 citedOpen Access
The Essential Role of Proteoglycans and Glycosaminoglycans in Odontogenesis
Journal of Dental Research·2024· 9 citedOpen Access
PB1316 Impact of Synonymous Gene Recoding on ADAMTS13
Research and Practice in Thrombosis and Haemostasis·2023Open Access
OC 04.5 Structural, Functional, and Immunogenicity Implications of F9 Gene Recoding
Research and Practice in Thrombosis and Haemostasis·2023Open Access
2022 MRC-ARL Summer Student Team Research Experience: Air-Deployed Robots for Mobile Sensing
2023Open Access
In silico methods for predicting functional synonymous variants
Genome biology·2023· 30 citedOpen Access
Implementing computational methods in tandem with synonymous gene recoding for therapeutic development
Trends in Pharmacological Sciences·2022· 18 cited
Structural, functional, and immunogenicity implications of <i>F9</i> gene recoding
Blood Advances·2022· 13 citedOpen Access
An Optimized Purification Design for Extracting Active ADAMTS13 from Conditioned Media
Processes·2022· 1 citedOpen Access
Methods to Evaluate the Effects of Synonymous Variants
2022· 1 cited
UBQLN proteins in health and disease with a focus on UBQLN2 in ALS/FTD
FEBS Journal·2021· 45 citedOpen Access
ALS/FTD mutations in UBQLN2 are linked to mitochondrial dysfunction through loss-of-function in mitochondrial protein import
Human Molecular Genetics·2021· 21 citedOpen Access
A Single Synonymous Variant (c.354G&gt;A [p.P118P]) in ADAMTS13 Confers Enhanced Specific Activity
International Journal of Molecular Sciences·2019· 27 citedOpen Access
Effects of codon optimization on coagulation factor IX translation and structure: Implications for protein and gene therapies
Scientific Reports·2019· 73 citedOpen Access
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Frequent Co-authors

Chava Kimchi‐Sarfaty(14), Anton A. Komar(11), Nobuko Hamasaki‐Katagiri(10), Upendra Katneni(9), Haim Bar(8), Ryan Hunt(7), Darón I. Freedberg(6), Zuben E. Sauna(6), David D. Holcomb(5), Michael DiCuccio(4), Katarzyna I. Jankowska(4), Robert Peters(3), Aikaterini Alexaki(3), Gaya Hettiarachchi(3), Jacob Kames(3), Nicole Higgins(3), Mervyn J. Monteiro(3), Douglas Meyer(3), Juan C. Ibla(3), Je‐Nie Phue(3)