Mark J. Crabtree

University of Surrey — United Kingdom

Medicine · Health Sciences

36h-index4.4kcitations112works4.32yr avg
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Research Topics

Nitric Oxide and Endothelin Effects(57), Cardiac Ischemia and Reperfusion(16), Mitochondrial Function and Pathology(15), Neutrophil, Myeloperoxidase and Oxidative Mechanisms(13), Eicosanoids and Hypertension Pharmacology(12)

Publications112 total

Formate reduces ischemic injury in the male heart by increasing protein S-nitrosation
2026
Declining nitric oxide bioavailability in cardiovascular aging: mechanistic insights and emerging interventions
The Journal of Cardiovascular Aging·2025Open Access
Formate yields protection from ischemic injury through a nitric oxide synthase-dependent increase in protein S-nitrosation
Journal of Molecular and Cellular Cardiology Plus·2025Open Access
PREDICT-EV, Identifying Novel Biomarkers to Predict Stroke Risk: A Nested, Case-controlled Clinical Trial Protocol <sup/>
Journal of Stroke Medicine·2025· 1 citedOpen Access
Synthesis and characterization of amine-functionalized graphene as a nitric oxide-generating coating for vascular stents
Applied Physics Reviews·2024· 7 citedOpen Access
pH-sensitive release of nitric oxide gas using peptide-graphene co-assembled hybrid nanosheets
Nitric Oxide·2024· 6 citedOpen Access
S-nitrosocysteamine-functionalised porous graphene oxide nanosheets as nitric oxide delivery vehicles for cardiovascular applications
Redox Biology·2024· 16 citedOpen Access
Nitric Oxide Releasing Nanomaterials for Cardiovascular Applications
JACC Basic to Translational Science·2023· 43 citedOpen Access
Cardiomyocyte tetrahydrobiopterin synthesis regulates fatty acid metabolism and susceptibility to ischaemia–reperfusion injury
Experimental Physiology·2023· 1 citedOpen Access
Crucial neuroprotective roles of the metabolite BH4 in dopaminergic neurons
2023· 6 citedOpen Access
Endothelial cell-specific roles for tetrahydrobiopterin in myocardial function, cardiac hypertrophy, and response to myocardial ischemia-reperfusion injury
American Journal of Physiology-Heart and Circulatory Physiology·2023· 11 citedOpen Access
Deletion of tetrahydrobiopterin synthesis in cardiomyocytes causes downregulation of fatty acid metabolism whilst protected against cardiac ischemia reperfusion injury
Journal of Molecular and Cellular Cardiology·2022
Biological Sensing of Nitric Oxide in Macrophages and Atherosclerosis Using a Ruthenium-Based Sensor
Biomedicines·2022· 9 citedOpen Access
Hepatic miR-144 drives fumarase activity preventing NRF2 activation during obesity
Journal of Hepatology·2022· 3 cited
Isolation and &lt;em&gt;In vitro&lt;/em&gt; Culture of Bone Marrow-Derived Macrophages for the Study of NO-Redox Biology
Journal of Visualized Experiments·2022· 4 cited
Isolation and &lt;em&gt;In vitro&lt;/em&gt; Culture of Bone Marrow-Derived Macrophages for the Study of NO-Redox Biology
Journal of Visualized Experiments·2022· 1 citedOpen Access
Cardiomyocyte Tetrahydrobiopterin Synthesis Regulates Fatty Acid Metabolism and Susceptibility to Ischemia Reperfusion Injury
SSRN Electronic Journal·2022Open Access
Itaconate as an inflammatory mediator and therapeutic target in cardiovascular medicine
Biochemical Society Transactions·2021· 13 citedOpen Access
Hepatic miR-144 Drives Fumarase Activity Preventing NRF2 Activation During Obesity
Gastroenterology·2021· 97 citedOpen Access
Hyperglycemia Induces Trained Immunity in Macrophages and Their Precursors and Promotes Atherosclerosis
PUBLISSO (German National Library of Medicine)·2021· 112 citedOpen Access
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Frequent Co-authors

Keith M. Channon(30), Ashley Hale(18), Eileen McNeill(11), Gillian Douglas(9), Nicholas J. C. King(8), Surawee Chuaiphichai(7), Jade Bailey(5), Marina Diotallevi(5), Jennifer K. Bendall(5), Steven S. Gross(5), Ricardo Carnicer(5), Barbara Casadei(5), Amy L. Tatham(4), Charalambos Antoniades(4), Jyoti Patel(4), T. NICOL(3), Andrew Shaw(3), Michael S. Goligorsky(3), Colin Cunnington(3), Robin P. Choudhury(3)