Jennifer K. Bendall

British Heart Foundation — United Kingdom

Medicine · Health Sciences

21h-index3.4kcitations34works0.02yr avg
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Research Topics

Nitric Oxide and Endothelin Effects(25), Neutrophil, Myeloperoxidase and Oxidative Mechanisms(7), Eicosanoids and Hypertension Pharmacology(7), Cardiac Ischemia and Reperfusion(6), Cardiovascular Function and Risk Factors(4)

Publications34 total

665 Immunotherapeutic trial in men with biochemical recurrence after definitive local therapy for prostate cancer: A clinical trial in progress
Regular and Young Investigator Award Abstracts·2023Open Access
Prime-boost immunotherapeutic trial in men with biochemical recurrence after definitive local therapy for prostate cancer.
Journal of Clinical Oncology·2023· 1 cited
Cardiomyocyte tetrahydrobiopterin synthesis regulates fatty acid metabolism and susceptibility to ischaemia–reperfusion injury
Experimental Physiology·2023· 1 citedOpen Access
Cardiomyocyte Tetrahydrobiopterin Synthesis Regulates Fatty Acid Metabolism and Susceptibility to Ischemia Reperfusion Injury
SSRN Electronic Journal·2022Open Access
Abstract CT151: Phase I study of KA2507, a selective HDAC6 inhibitor, in patients with relapsed or refractory solid tumors
Cancer Research·2020· 3 cited
A phase II study of selective HDAC6 inhibition with KA2507 for second-line treatment of advanced biliary tract cancer (ABC-11).
Journal of Clinical Oncology·2020· 3 cited
Endothelial Cell–Specific Reactive Oxygen Species Production Increases Susceptibility to Aortic Dissection
Circulation·2014· 123 citedOpen Access
Abstract 167: A Cell-Autonomous Role for Endothelial GTP Cyclohydrolase 1 and Tetrahydrobiopterin in Blood Pressure Regulation
Arteriosclerosis Thrombosis and Vascular Biology·2014
Cell-Autonomous Role of Endothelial GTP Cyclohydrolase 1 and Tetrahydrobiopterin in Blood Pressure Regulation
Hypertension·2014· 59 citedOpen Access
Tetrahydrobiopterin in Cardiovascular Health and Disease
Antioxidants and Redox Signaling·2013· 225 citedOpen Access
Cardiomyocyte GTP Cyclohydrolase 1 and Tetrahydrobiopterin Increase NOS1 Activity and Accelerate Myocardial Relaxation
Circulation Research·2012· 43 cited
The relative contributions of cardiomyocytes versus endothelial cells to cardiac BH4 production; studies in novel cardiomyocyte- and endothelial-specific GTPCH I-deficient mice
Nitric Oxide·2012
Endothelial-specific Nox2 overexpression increases vascular superoxide and macrophage recruitment in ApoE−/− mice
Cardiovascular Research·2012· 108 citedOpen Access
Acute Inflammation Rapidly Increases Plasma Biopterins and Impairs Endothelial Function: A Novel Role of Plasma Tetrahydrobiopterin as a Marker of Acute Inflammation
Oxford University Research Archive (ORA) (University of Oxford)·2011
Induction of Vascular GTP-Cyclohydrolase I and Endogenous Tetrahydrobiopterin Synthesis Protect Against Inflammation-Induced Endothelial Dysfunction in Human Atherosclerosis
Circulation·2011· 71 citedOpen Access
Rapid, Direct Effects of Statin Treatment on Arterial Redox State and Nitric Oxide Bioavailability in Human Atherosclerosis via Tetrahydrobiopterin-Mediated Endothelial Nitric Oxide Synthase Coupling
Circulation·2011· 217 citedOpen Access
Targeting Redox Signaling in the Vascular Wall: From Basic Science to Clinical Practice
Current Pharmaceutical Design·2009· 68 cited
CCR2-Mediated Antiinflammatory Effects of Endothelial Tetrahydrobiopterin Inhibit Vascular Injury-Induced Accelerated Atherosclerosis
Circulation·2008· 28 citedOpen Access
Endothelial overexpression of Nox2 in transgenic mice potentiates vascular oxidative stress and the pressor response to angiotensin II
Atherosclerosis·2007
Endothelial Nox2 Overexpression Potentiates Vascular Oxidative Stress and Hemodynamic Response to Angiotensin II
Circulation Research·2007· 153 cited
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Frequent Co-authors

Keith M. Channon(21), Nicholas J. C. King(9), Christophe Heymes(8), Gillian Douglas(8), Mark J. Crabtree(8), Ashley Hale(8), Philippe Ratajczak(5), Alison Cave(5), Jane‐Lise Samuel(5), Ajay M. Shah(5), Eileen McNeill(5), Amy L. Tatham(5), Surawee Chuaiphichai(5), Charalambos Antoniades(4), Alexios S. Antonopoulos(4), Dimitris Tousoulis(3), Michael Demosthenous(3), Barbara Casadei(3), Christodoulos Stefanadis(3), David Adlam(3)