Victor R. DeFilippis

Oregon National Primate Research Center — United States

Immunology and Microbiology · Life Sciences

36h-index4.0kcitations84works1.82yr avg
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Research Topics

interferon and immune responses(33), Mosquito-borne diseases and control(27), Viral Infections and Vectors(24), Cytomegalovirus and herpesvirus research(19), Immune Response and Inflammation(8)

Publications84 total

A Zika Virus-Like Particle Vaccine Mitigates Early Pregnancy Loss In Rhesus Macaques
2025Open Access
In silico discovery and mechanistic profiling of STING agonists engaging the transmembrane domain
European Journal of Medicinal Chemistry·2025Open Access
Characterization of a Novel Transmembrane Activating STING Agonist using Genetically Humanized Mice
2025· 1 citedOpen Access
Comparative molecular, innate, and adaptive impacts of chemically diverse STING agonists
Vaccine·2025· 2 citedOpen Access
Comparative Molecular, Innate, and Adaptive Impacts of Chemically Diverse STING Agonists
2025· 1 citedOpen Access
In Silico Discovery and Mechanistic Profiling of Sting Agonists Engaging the Transmembrane Domain
SSRN Electronic Journal·2025Open Access
4-Substituted-2-Thiazole Amides as Viral Replication Inhibitors of Alphaviruses
Journal of Medicinal Chemistry·2024· 5 cited
Bystander monocytic cells drive infection-independent NLRP3 inflammasome response to SARS-CoV-2
mBio·2024· 5 citedOpen Access
Mayaro virus pathogenesis and immunity in rhesus macaques
PLoS neglected tropical diseases·2023· 15 citedOpen Access
Aging alters antiviral signaling pathways resulting in functional impairment in innate immunity in response to pattern recognition receptor agonists
GeroScience·2022· 19 citedOpen Access
Development of a next-generation chikungunya virus vaccine based on the HydroVax platform
PLoS Pathogens·2022· 19 citedOpen Access
Identification and Characterization of Small-Molecule IRF3-Dependent Immune Activators for Pharmaceutical Development
ACS Chemical Biology·2022Open Access
Human cytomegalovirus blocks canonical TGFβ signaling during lytic infection to limit induction of type I interferons
PLoS Pathogens·2021· 9 citedOpen Access
Identification of Quinolinones as Antivirals against Venezuelan Equine Encephalitis Virus
Antimicrobial Agents and Chemotherapy·2021· 12 citedOpen Access
Divergent immune impacts elicited by chemically dissimilar agonists of the STING protein
The Journal of Immunology·2021· 1 cited
Targeting Chikungunya Virus Replication by Benzoannulene Inhibitors
Journal of Medicinal Chemistry·2021· 22 citedOpen Access
Non-replicating adenovirus based Mayaro virus vaccine elicits protective immune responses and cross protects against other alphaviruses
PLoS neglected tropical diseases·2021· 23 citedOpen Access
Human cytomegalovirus blocks canonical TGFβ signaling during lytic infection to limit induction of type I interferons
2021Open Access
Characterization of a Novel Compound That Stimulates STING-Mediated Innate Immune Activity in an Allele-Specific Manner
Frontiers in Immunology·2020· 17 citedOpen Access
Vaccine-induced skewing of t cell responses protects against chikungunya virus disease
UNC Libraries·2020Open Access
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Frequent Co-authors

Daniel N. Streblow(21), Klaus Früh(20), Craig N. Kreklywich(12), Patricia P. Smith(10), Rebecca M. Broeckel(9), Alec J. Hirsch(8), Jay A. Nelson(8), Jessica L. Smith(7), Nicole N. Haese(7), Tina M. Sali(6), Michael Denton(5), Michael K. Axthelm(5), Ashlee V. Moses(5), Kara Pryke(5), Thomas E. Morrison(5), Mark T. Heise(5), Alfred W. Legasse(4), Luis P. Villarreal(4), Daniel Malouli(4), Jinu Abraham(4)