Nadine L. Vastenhouw

Swiss Integrative Center for Human Health — Switzerland

Biochemistry, Genetics and Molecular Biology · Life Sciences

24h-index4.0kcitations63works5.52yr avg
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Research Topics

Genomics and Chromatin Dynamics(27), RNA Research and Splicing(21), Epigenetics and DNA Methylation(15), CRISPR and Genetic Engineering(11), RNA modifications and cancer(6)

Publications63 total

<i>In vivo</i> genome-wide CRISPRi-Seq in <i>Streptococcus pneumoniae</i> reveals host-adaptive pathways essential for meningitis and identifies new therapeutic targets
2025Open Access
Multiplexed embryo profiling links cellular state to zygotic genome activation in single cells
2025Open Access
Specificity in clustering of gene-specific transcription factors is encoded in the genome
Nucleic Acids Research·2025Open Access
Structured Detection for Enhanced Resolution and Optical Sectioning Microscopy
2025
Structured detection for simultaneous super-resolution and optical sectioning in laser scanning microscopy
Nature Photonics·2025· 11 citedOpen Access
Probing condensate microenvironments with a micropeptide killswitch
Nature·2025· 16 citedOpen Access
The role of transcription bodies in gene expression: what embryos teach us
Biochemical Society Transactions·2025Open Access
Imaging Nuclear Clusters in Live Zebrafish Embryos
Methods in molecular biology·2025
Specificity in transcription factor clustering is encoded in the genome
2024· 5 citedOpen Access
Local DNA compaction creates TF-DNA clusters that enable transcription
2024· 8 citedOpen Access
Transcription bodies regulate gene expression by sequestering CDK9
Nature Cell Biology·2024· 21 citedOpen Access
Sleeping embryonic genomes are awoken by OBOX proteins
Nature·2023· 1 cited
Scripts &amp; Raw data - developmental staging of zebrafish embryos based on intra-nuclear distances
Zenodo (CERN European Organization for Nuclear Research)·2023Open Access
Scripts &amp; Raw data - developmental staging of zebrafish embryos based on intra-nuclear distances
Zenodo (CERN European Organization for Nuclear Research)·2023Open Access
Actin filaments accumulated in the nucleus remain in the vicinity of condensing chromosomes in the zebrafish early embryo
Biology Open·2023· 9 citedOpen Access
Nanog organizes transcription bodies
Current Biology·2022· 30 cited
Transcription bodies regulate gene expression by sequestering CDK9
2022· 1 citedOpen Access
Actin filaments accumulate in the nucleus during interphase and remain in the vicinity of condensing chromosomes during prophase to metaphase in zebrafish early embryos
2022Open Access
Nanog organizes transcription bodies
2022· 3 citedOpen Access
Maternally loaded RNAs: no time to die
Cell Research·2022Open Access
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Frequent Co-authors

Lennart Hilbert(12), Hiroshi Kimurâ(11), Vasily Zaburdaev(10), Shai R. Joseph(8), Yuko Sato(8), Haruka Oda(8), Máté Pálfy(7), Ronald H.A. Plasterk(6), Ksenia Kuznetsova(6), Edlyn Wu(6), Mukesh Kumar(5), Andrej Shevchenko(5), Alexander F. Schier(4), David Drechsel(4), Florian Jug(4), Martino Ugolini(4), Eivind Valen(3), Aviv Regev(3), Yong Zhang(3), X. Shirley Liu(3)