Andrew E. Arrant

Civitan International — United States

Medicine · Health Sciences

17h-index1.4kcitations46works1.42yr avg
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Research Topics

Amyotrophic Lateral Sclerosis Research(25), Parkinson's Disease Mechanisms and Treatments(18), Alzheimer's disease research and treatments(15), Neurotransmitter Receptor Influence on Behavior(10), Neurogenetic and Muscular Disorders Research(6)

Publications46 total

Delivering Progranulin to Astrocytic Lysosomes Promotes Growth of Co‐Cultured Neurons
Journal of Neurochemistry·2025Open Access
Author response for "Delivering Progranulin to Astrocytic Lysosomes Promotes Growth of Co‐Cultured Neurons"
2025
Author response for "Delivering Progranulin to Astrocytic Lysosomes Promotes Growth of Co‐Cultured Neurons"
2025
TFEB overexpression alleviates autophagy-lysosomal deficits caused by progranulin insufficiency
Scientific Reports·2025· 3 citedOpen Access
Reduction of sphingomyelinase activity associated with progranulin deficiency and frontotemporal dementia
Neurobiology of Disease·2025· 1 citedOpen Access
Assessing Social Dominance in Mouse Models Using the Tube Test
Journal of Visualized Experiments·2025
Progranulin acts in lysosomes to promote neuronal survival and growth
Alzheimer s & Dementia·2024Open Access
Increased levels of extracellular matrix proteins associated with extracellular vesicles from brains of aged mice
Aging Cell·2024· 4 citedOpen Access
Carboxy-terminal blockade of sortilin binding enhances progranulin gene therapy, a potential treatment for frontotemporal dementia
2024· 2 citedOpen Access
Dendritic spine head diameter is reduced in the prefrontal cortex of progranulin haploinsufficient mice
Molecular Brain·2024· 2 citedOpen Access
Adolescent stress accelerates postpartum novelty recognition impairment in 5xFAD mice
Frontiers in Neuroscience·2024· 3 citedOpen Access
Regulation of extracellular progranulin in the medial prefrontal cortex
Alzheimer s & Dementia·2023Open Access
Regulation of extracellular progranulin in medial prefrontal cortex
Neurobiology of Disease·2023· 4 citedOpen Access
Latozinemab, a novel progranulin-elevating therapy for frontotemporal dementia
Journal of Translational Medicine·2023· 44 citedOpen Access
Patients with sporadic FTLD exhibit similar increases in lysosomal proteins and storage material as patients with FTD due to GRN mutations
Acta Neuropathologica Communications·2023· 14 citedOpen Access
Similar lysosomal abnormalities in cortex of patients with sporadic FTLD‐TDP type A and patients with FTD‐<i>GRN</i>
Alzheimer s & Dementia·2022
Development of the Monoclonal Antibody AL101 to block the Sortilin/Progranulin Interaction as a Potential Therapy for Neurodegenerative Diseases (P6-3.003)
Neurology·2022
Delivering progranulin to neuronal lysosomes protects against excitotoxicity
Journal of Biological Chemistry·2021· 27 citedOpen Access
Elevated levels of extracellular vesicles in progranulin‐deficient mice and FTD‐<i>GRN</i> Patients
Annals of Clinical and Translational Neurology·2020· 13 citedOpen Access
Behavioral defects associated with amygdala and cortical dysfunction in mice with seeded α-synuclein inclusions
Neurobiology of Disease·2019· 87 citedOpen Access
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Frequent Co-authors

Erik D. Roberson(19), Cynthia M. Kuhn(9), Bruce L. Miller(8), William W. Seeley(8), Azariah K. Kaplelach(8), Charles Murchison(7), Skylar E. Davis(7), Justin A. Hall(7), Alissa L. Nana(6), Salvatore Spina(6), Lea T. Grinberg(6), Anthony J. Filiano(5), Nicholas R. Boyle(5), Ahmad R. Hakim(5), Michael E. Ward(4), Jonathan R. Roth(4), Shreya Kashyap(4), Amanda E.D. Van Swearingen(4), Anna K. Cook(4), Stephanie N. Fox(4)