Kyle J. Horning

University of Arizona — United States

Neuroscience · Life Sciences

9h-index850citations15works0.02yr avg
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Research Topics

Autism Spectrum Disorder Research(4), Trace Elements in Health(4), Genetics and Neurodevelopmental Disorders(4), Epilepsy research and treatment(3), Heavy Metal Exposure and Toxicity(3)

Publications15 total

Distinguishing Loss-of-Function and Gain-of-Function <i>SCN8A</i> Variants Using a Random Forest Classification Model Trained on Clinical Features
Neurology Genetics·2023· 31 citedOpen Access
Patterns of developmental regression and associated clinical characteristics in SLC6A1-related disorder
Frontiers in Neuroscience·2023· 10 citedOpen Access
A draft conceptual model of SLC6A1 neurodevelopmental disorder
Frontiers in Neuroscience·2023· 13 citedOpen Access
A disease concept model for <i>STXBP1</i> ‐related disorders
Epilepsia Open·2023· 24 citedOpen Access
A disease concept model for <i>STXBP1</i> -related disorders
2022· 1 citedOpen Access
Identification of Three Small Molecules That Can Selectively Influence Cellular Manganese Levels in a Mouse Striatal Cell Model
Molecules·2021Open Access
A Small-Molecule Modulator of Metal Homeostasis in Gram-Positive Pathogens
mBio·2020· 17 citedOpen Access
Identification of a selective manganese ionophore that enables nonlethal quantification of cellular manganese
Journal of Biological Chemistry·2020· 8 citedOpen Access
Small Molecule Modifiers of In Vitro Manganese Transport Alter Toxicity In Vivo
Biological Trace Element Research·2018· 6 cited
Sigma‐1 receptor ligands inhibit catecholamine secretion from adrenal chromaffin cells due to block of nicotinic acetylcholine receptors
Journal of Neurochemistry·2017· 9 citedOpen Access
Reduced bioavailable manganese causes striatal urea cycle pathology in Huntington's disease mouse model
Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease·2017· 43 citedOpen Access
Role of<scp>d</scp>‐amino acid oxidase in the production of kynurenine pathway metabolites from<scp>d</scp>‐tryptophan in mice
Journal of Neurochemistry·2015· 22 citedOpen Access
Manganese Is Essential for Neuronal Health
Annual Review of Nutrition·2015· 577 cited
Evaluation of kynurenine pathway metabolism in Toxoplasma gondii-infected mice: Implications for schizophrenia
Schizophrenia Research·2013· 85 citedOpen Access
A method for the determination of d-kynurenine in biological tissues
Analytical and Bioanalytical Chemistry·2013· 4 cited

Frequent Co-authors

Aaron B. Bowman(6), Michael Aschner(5), Terry Jo Bichell(5), Francesca M. Notarangelo(3), Robert Schwarcz(3), Anna C. Pfalzer(3), Nicole C. Weitzel(3), K. Grace Tipps(2), Katie Rose Sullivan(2), Sarah M. Ruggiero(2), Julie Xian(2), Kim Marie Thalwitzer(2), Sydni Stewart(2), Mahgenn Cosico(2), Jackie Steinberg(2), James Goss(2), Sydney Corey(2), Laura Conway(2), Charlene Son Rigby(2), Ingo Helbig(2)