James Adjaye

National Institute for Health Research — United Kingdom

Biochemistry, Genetics and Molecular Biology · Life Sciences

57h-index9.6kcitations300works1.72yr avg
OpenAlex↗ORCID↗Google Scholar↗Lab page↗

Accepting Students?

No reports yet. Know if this professor is taking students?

Research Topics

Pluripotent Stem Cells Research(124), CRISPR and Genetic Engineering(65), Renal and related cancers(63), Epigenetics and DNA Methylation(25), Mesenchymal stem cell research(24)

Publications300 total

Modelling APOL1-mediated kidney inflammation and fibrosis using a partially reprogrammed urine-derived SIX2-positive renal progenitor cell line
Stem Cell Research & Therapy·2025Open Access
Urinary proteins from Sickle Cell patients induce inflammation and kidney injury via the TGFβ-p53 axis in a podocyte cell culture model
2025Open Access
Modelling APOL1-mediated kidney inflammation and fibrosis using a partially reprogrammed urine derived SIX2-positive renal progenitor cell line
2025Open Access
Human Urine-derived SIX2-positive renal progenitor cells improve kidney injury in an IRI mouse model
2025Open Access
Generation of an induced pluripotent stem cell line HHUUKDi013-A (ISRM-AATD-iPSC-3) from a pediatric patient of Alpha-I Antitrypsin Deficiency (AATD)
Stem Cell Research·2025Open Access
Generation of a Bartter syndrome type 3 patient-derived induced pluripotent stem cell line ISRM-BS3-UM18-iPSC (HHUUKDi014-A)
Stem Cell Research·2025· 2 citedOpen Access
POS0250 INDUCED PLURIPOTENT STEM CELL-DERIVED TISSUE RESIDENT MACROPHAGE INDUCE PROFIBROTIC FIBROBLAST RESPONSES IN ORGANOTYPIC SKIN MODELS OF SYSTEMIC SCLEROSIS
Annals of the Rheumatic Diseases·2025Open Access
OP0011 In vitro modelling of vasculopathy in systemic sclerosis by human blood vessel organoids
Annals of the Rheumatic Diseases·2025Open Access
Impact of nephrotoxins and oxidants on survival and transport function of hiPSC-derived renal proximal tubular cells
Archives of Toxicology·2025Open Access
Evidence for conserved gene expression and biological processes operative in human podocytes and adult brain
2025Open Access
Impact of nephrotoxins and oxidants on survival and transport function of hiPSC-derived renal proximal tubular cells
2025Open Access
Investigating BPDE-induced embryonic toxicity employing hiPSC-based models
2024· 1 citedOpen Access
Publisher Correction: Hemozoin induces malaria via activation of DNA damage, p38 MAPK and neurodegenerative pathways in a human iPSC-derived neuronal model of cerebral malaria
Scientific Reports·2024Open Access
DPP4 inhibition affects metabolism and inflammation associated pathways in hiPSC-derived steatotic HLCs
2024Open Access
Hemozoin induces malaria via activation of DNA damage, p38 MAPK and neurodegenerative pathways in a human iPSC-derived neuronal model of cerebral malaria
Scientific Reports·2024· 9 citedOpen Access
Untangling the Uncertain Role of Overactivation of the Renin–Angiotensin–Aldosterone System with the Aging Process Based on Sodium Wasting Human Models
International Journal of Molecular Sciences·2024· 4 citedOpen Access
Genexpressionsprofile beim Porokarzinom deuten auf heterogene Tumorentwicklung hin und untermauern Porome als Vorläuferläsionen
JDDG Journal der Deutschen Dermatologischen Gesellschaft·2024Open Access
Single cell data enables dissecting cell types present in bulk transcriptome data
2024Open Access
Sodium Deficiency Diseases: The Association With the Renin-Angiotensin-Aldosterone System, Aging and Inflammation
Preprints.org·2024· 2 citedOpen Access
Gene expression profiling in porocarcinoma indicates heterogeneous tumor development and substantiates poromas as precursor lesions
JDDG Journal der Deutschen Dermatologischen Gesellschaft·2024· 1 citedOpen Access
page 1 of 15Next →

Frequent Co-authors

Hans Lehrach(20), Alessandro Prigione(13), Thore C. Brink(9), Wasco Wruck(8), Ralf Herwig(7), Christos C. Zouboulis(7), Justyna Józefczuk(6), Boris Greber(5), Lucas‐Sebastian Spitzhorn(5), Md Shaifur Rahman(5), Evgenia Makrantonaki(5), Beatrix Fauler(4), Matthias Megges(4), Detlef Groth(4), Katharina Drews(4), Amir M. Hossini(4), Barbara Mlody(3), Raul Bukowiecki(3), Claus Hultschig(3), Lukas Chávez(3)