John H. Exton

Vanderbilt University — United States

Biochemistry, Genetics and Molecular Biology · Life Sciences

95h-index31.4kcitations317works0.02yr avg
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Research Topics

Protein Kinase Regulation and GTPase Signaling(111), Pancreatic function and diabetes(79), Metabolism, Diabetes, and Cancer(55), Receptor Mechanisms and Signaling(43), Cellular transport and secretion(36)

Publications317 total

G-proteins | G Protein Signaling Regulators
Elsevier eBooks·2021
Phospholipases
2008
In Search of the Message
Journal of Biological Chemistry·2008Open Access
Phospholipase D—Structure, regulation and function
Reviews of physiology, biochemistry and pharmacology·2007· 234 cited
Regulation of Phosphoinositide and Phosphatidylcholine Phospholipases by G Proteins
Novartis Foundation symposium·2007· 6 cited
The Regulation of Glucose Uptake in Muscle: the Work of Charles R. Park
Journal of Biological Chemistry·2007Open Access
Biochemical Analysis of Phospholipase D
Methods in enzymology on CD-ROM/Methods in enzymology·2007· 88 cited
Autocrine Tumor Necrosis Factor Alpha Links Endoplasmic Reticulum Stress to the Membrane Death Receptor Pathway through IRE1α-Mediated NF-κB Activation and Down-Regulation of TRAF2 Expression
Molecular and Cellular Biology·2006· 738 citedOpen Access
Phospholipase D, Arfaptins and Arfophilin
Kluwer Academic Publishers eBooks·2006
The roles of calcium and phosphoinositides in the mechanisms of α 1-adrenergic and other agonists
Reviews of physiology, biochemistry and pharmacology·2005· 46 cited
Kinetic Analysis of a Mammalian Phospholipase D
Journal of Biological Chemistry·2005· 64 citedOpen Access
Role of heterotrimeric G-proteins in lysophosphatidic acid-mediated neurite retraction by RhoA-dependent and -independent mechanisms in N1E-115 cells
Cellular Signalling·2005· 9 cited
Sites on phospholipase D2 phosphorylated by PKCα
Biochemical and Biophysical Research Communications·2005· 5 cited
A point mutation at phenylalanine 663 abolishes protein kinase Cα’s ability to translocate to the perinuclear region and activate phospholipase D1
Biochemical and Biophysical Research Communications·2005· 5 cited
Identification of interaction sites of protein kinase Cα on phospholipase D1
Cellular Signalling·2005· 22 cited
Localization and regulation of phospholipase D2 by ARF6
Journal of Cellular Biochemistry·2005· 40 cited
Requirement of phospholipase D1 activity in H-Ras <sup>V12</sup> -induced transformation
Proceedings of the National Academy of Sciences·2005· 63 citedOpen Access
Assays and Properties of Arfaptin 2 Binding to Rac1 and ADP‐Ribosylation Factors (Arfs)
Methods in enzymology on CD-ROM/Methods in enzymology·2005· 6 cited
1-Butanol interferes with phospholipase D1 and protein kinase Cα association and inhibits phospholipase D1 basal activity
Biochemical and Biophysical Research Communications·2004· 25 cited
Tyrosine phosphorylation of phospholipase D1 by v-Src does not per se result in activation
Cellular Signalling·2004· 11 cited
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Frequent Co-authors

P F Blackmore(11), C.R. Park(4), Stephen Bocckino(4), R Charest(4), Lawrence E. Mallette(3), Jonathan L. Blank(3), Veronica Prpić(3), C R Park(3), Hiroyuki Nakanishi(2), Kim Brewer(2), Ping Hu(2), Han Zhang(2), Anthony D. Couvillon(2), Gabriel Berstein(2), Elliott M. Ross(2), R.W. Butcher(2), Earl W. Sutherland(2), C. R. Park(2), G. Alan Robison(2), F D Assimacopoulos-Jeannet(2)