Daniel B. McClatchy

Scripps Research Institute — United States

Chemistry · Physical Sciences

29h-index3.1kcitations80works5.62yr avg
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Research Topics

Advanced Proteomics Techniques and Applications(35), Mass Spectrometry Techniques and Applications(20), Metabolomics and Mass Spectrometry Studies(13), Biotin and Related Studies(11), Ubiquitin and proteasome pathways(10)

Publications80 total

Quantitative Proteomic Analysis Reveals JMJD6 and DNAJB11 as Endogenous Substrates of E3 Ligase RFFL
Journal of Proteome Research·2025· 1 cited
PrP <sup>C</sup> -induced signaling in human neurons activates phospholipase Cɣ1 and an Arc/Arg3.1 response
2025· 1 citedOpen Access
Native top-down proteomics enables discovery in endocrine-resistant breast cancer
Nature Chemical Biology·2025· 14 cited
Mutant prion protein enhances NMDA receptor activity, activates PKC, and triggers rapid excitotoxicity in mice
Journal of Clinical Investigation·2025· 4 citedOpen Access
Activity-dependent synthesis of Emerin gates neuronal plasticity by regulating proteostasis
Cell Reports·2025· 3 citedOpen Access
Insights into Free Drug Release from Efficacious <i>N</i>-Acyl <i>O</i>-Aminophenol Duocarmycin Prodrugs
ACS Chemical Biology·2025Open Access
Acid Cleavable Biotin-Alkyne Improves Sensitivity for Direct Detection of Biotin Labeled Peptides in Biorthogonal Noncanonical Amino Acid Tagging Analysis
Journal of Proteome Research·2024· 1 citedOpen Access
Using in vivo intact structure for system-wide quantitative analysis of changes in proteins
Nature Communications·2024· 6 citedOpen Access
DiDBiT-TMT: A Novel Method to Quantify Changes in the Proteomic Landscape Induced by Neural Plasticity
Journal of Proteome Research·2024
Do Perineuronal Nets Stabilize the Engram of a Synaptic Circuit?
Cells·2024· 7 citedOpen Access
Author Reply to Peer Reviews of In vivo mapping of protein-protein interactions of schizophrenia risk factors generates an interconnected disease network.
2024
Acid cleavable biotin-alkyne improves sensitivity for direct detection of biotin labeled peptides in BONCAT analysis
2024Open Access
Activity-dependent synthesis of Emerin gates neuronal plasticity by regulating proteostasis
2024· 1 citedOpen Access
WITHDRAWN: DiDBiT-TMT: A novel method to quantify changes in the proteomic landscape induced by neural plasticity
2024Open Access
Quantitative analysis of proteostasis networks: are there applications for dementia?
Expert Review of Proteomics·2024· 3 citedOpen Access
Phosphorylation of pyruvate dehydrogenase inversely associates with neuronal activity
Neuron·2024· 48 citedOpen Access
In vivo mapping of protein-protein interactions of schizophrenia risk factors generates an interconnected disease network
2023Open Access
Mocetinostat activates Krüppel-like factor 4 and protects against tissue destruction and inflammation in osteoarthritis
JCI Insight·2023· 21 citedOpen Access
Native top-down proteomics reveals EGFR–ERα signaling crosstalk in breast cancer cells dissociates NUTF2 dimers to modulate ERα signaling and cell growth
2023· 3 citedOpen Access
Using In Vivo Intact Structure for System-wide Quantitative Analysis of Changes in Proteins
2023Open Access
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Frequent Co-authors

John R. Yates(44), Salvador Martínez‐Bartolomé(10), Sung Kyu Park(9), Hollis T. Cline(8), Yuanhui Ma(8), Lucio Schiapparelli(7), Jolene K. Diedrich(6), Lujian Liao(6), Pranav Sharma(5), Bingwen Lu(5), Han-Hsuan Liu(4), Navin Rauniyar(4), Mathieu Lavallée‐Adam(4), John D. Venable(3), Nam‐Kyung Yu(3), Tao Xu(3), Alysson R. Muotri(2), Carolina Fernández-Costa(2), Anthony J. Saviola(2), Pamela Maher(2)