Nanako Masada

University of Cambridge — United Kingdom

Biochemistry, Genetics and Molecular Biology · Life Sciences

14h-index794citations17works0.02yr avg
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Research Topics

Phosphodiesterase function and regulation(7), Protein Kinase Regulation and GTPase Signaling(6), Receptor Mechanisms and Signaling(6), Ion channel regulation and function(4), Neuroscience and Neuropharmacology Research(3)

Publications17 total

High-throughput screening identifies Ceefourin 1 and Ceefourin 2 as highly selective inhibitors of multidrug resistance protein 4 (MRP4)
Biochemical Pharmacology·2014· 69 citedOpen Access
Hoch funktionalisierte Terpyridine als kompetitive Inhibitoren von AKAP‐PKA‐Wechselwirkungen
Angewandte Chemie·2013· 6 citedOpen Access
Highly Functionalized Terpyridines as Competitive Inhibitors of AKAP–PKA Interactions
Angewandte Chemie International Edition·2013· 50 citedOpen Access
Distinct Mechanisms of Calmodulin Binding and Regulation of Adenylyl Cyclases 1 and 8
Biochemistry·2012· 37 citedOpen Access
Distinct mechanisms of regulation by Ca2+/calmodulin of type 1 and 8 adenylyl cyclases support their different physiological roles.
Journal of Biological Chemistry·2010· 2 citedOpen Access
AKAP79/150 Interacts with AC8 and Regulates Ca2+-dependent cAMP Synthesis in Pancreatic and Neuronal Systems
Journal of Biological Chemistry·2010· 81 citedOpen Access
Distinct pools of cAMP centre on different isoforms of adenylyl cyclase in pituitary-derived GH3B6 cells
Journal of Cell Science·2009· 77 citedOpen Access
Direct demonstration of discrete Ca2+ microdomains associated with different isoforms of adenylyl cyclase
Journal of Cell Science·2009· 55 citedOpen Access
Structural Basis for Inhibition of Mammalian Adenylyl Cyclase by Calcium
Biochemistry·2009· 65 citedOpen Access
Insights into the residence in lipid rafts of adenylyl cyclase AC8 and its regulation by capacitative calcium entry
American Journal of Physiology-Cell Physiology·2009· 45 citedOpen Access
Distinct Mechanisms of Regulation by Ca2+/Calmodulin of Type 1 and 8 Adenylyl Cyclases Support Their Different Physiological Roles
Journal of Biological Chemistry·2008· 54 citedOpen Access
Kinetic properties of Ca2+/calmodulin-dependent phosphodiesterase isoforms dictate intracellular cAMP dynamics in response to elevation of cytosolic Ca2+
Cellular Signalling·2007· 29 cited
Localized Na+/H+ Exchanger 1 Expression Protects Ca2+-regulated Adenylyl Cyclases from Changes in Intracellular pH
Journal of Biological Chemistry·2005· 45 citedOpen Access
Aldosterone stimulates active Na+ transport in rabbit urinary bladder by both genomic and non-genomic processes
European Journal of Pharmacology·2005· 6 cited
The Cytosolic Domains of Ca2+-sensitive Adenylyl Cyclases Dictate Their Targeting to Plasma Membrane Lipid Rafts
Journal of Biological Chemistry·2004· 86 citedOpen Access
Sustained Entry of Ca2+ Is Required to Activate Ca2+-Calmodulin-dependent Phosphodiesterase 1A
Journal of Biological Chemistry·2004· 29 citedOpen Access
Coordinate regulation of membrane cAMP by Ca<sup>2+</sup>-inhibited adenylyl cyclase and phosphodiesterase activities
American Journal of Physiology-Lung Cellular and Molecular Physiology·2003· 58 cited

Frequent Co-authors

Dermot M.F. Cooper(17), Antonio Ciruela(9), Debbie Willoughby(4), Sebastian Wachten(4), Andrew J. Crossthwaite(2), Mario Pagano(2), Laura-Jo Ayling(2), D. MacDougall(2), Gesa Schäfer(2), Jelena Milić(2), Adeeb El‐Dahshan(2), Frank Götz(2), Kerstin Zühlke(2), Christian Schillinger(2), Annika Kreuchwig(2), Jonathan M. Elkins(2), Kamal R. Abdul Azeez(2), Andreas Oder(2), Marie Christine Moutty(2), Monika Beerbaum(2)