Robert G. Vries

Merck (Germany) — Germany

Medicine · Health Sciences

20h-index11.2kcitations41works5.62yr avg
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Research Topics

Cancer Cells and Metastasis(14), Liver physiology and pathology(6), Pancreatic function and diabetes(5), Wnt/β-catenin signaling in development and cancer(5), Cancer Genomics and Diagnostics(5)

Publications41 total

Single‐cell multi‐omics characterize colorectal tumors, adjacent healthy tissue and matched (tumor) organoids identifying <scp>CRC</scp> ‐unique features
International Journal of Cancer·2025· 2 citedOpen Access
Tu2051: RECONSTRUCTING TUMOUR MICROENVIRONMENT WITH PATIENT-DERIVED ORGANOIDS FOR DERISKING IMMUNO-ONCOLOGY THERAPIES
Gastroenterology·2025
Tu2047: 3D IN-VITRO FIBROBLAST-PATIENT DERIVED ORGANOID CO-CULTURE: A HIGH-THROUGHPUT PLATFORM FOR IBD DRUG DEVELOPMENT
Gastroenterology·2025
Tu2022: PATIENT DERIVED ORGANOID MONOLAYERS: A PHYSIOLOGICALLY RELEVANT PLATFORM FOR EVALUATING THERAPEUTIC MODALITIES IN IBD
Gastroenterology·2025
306. Patient-Derived Airway Organoids: a Pre-clinical Platform to Model RSV Infection
Open Forum Infectious Diseases·2025Open Access
P-1821. Patient-Derived Airway Organoids for Modelling and Modulating <i>Rhinovirus</i> infection
Open Forum Infectious Diseases·2025Open Access
Abstract 5174: Organoids to predict treatment response in metastatic colorectal cancer (OPTIC)
Cancer Research·2024
Organoids as a biomarker for personalized treatment in metastatic colorectal cancer: drug screen optimization and correlation with patient response
Journal of Experimental & Clinical Cancer Research·2024· 43 citedOpen Access
Organoids as a biomarker for personalized treatment in metastatic colorectal cancer: drug screen optimization and correlation with patient response
Research Square (Research Square)·2023· 1 citedOpen Access
Abstract 151: Optimization of screening conditions using patient-derived organoids for diagnostic purposes
Cancer Research·2023· 1 cited
A living biobank of matched pairs of patient-derived xenografts and organoids for cancer pharmacology
PLoS ONE·2023· 20 citedOpen Access
Molecular and Functional Characterization of Human Intestinal Organoids and Monolayers for Modeling Epithelial Barrier
Inflammatory Bowel Diseases·2022· 52 citedOpen Access
Organoid-Derived Epithelial Monolayer: A Clinically Relevant In Vitro Model for Intestinal Barrier Function
Journal of Visualized Experiments·2021· 4 cited
Organoid-Derived Epithelial Monolayer: A Clinically Relevant In Vitro Model for Intestinal Barrier Function
Journal of Visualized Experiments·2021· 19 cited
Abstract 126: HUB Organoids: bringing the 'patient in the lab' for preclinical and clinical development
Cancer Research·2021· 1 cited
Long-Term Survival of Transplanted Autologous Canine Liver Organoids in a COMMD1-Deficient Dog Model of Metabolic Liver Disease
Cells·2020· 51 citedOpen Access
The Organoid Cell Atlas: A Rosetta Stone for Biomedical Discovery and Regenerative Therapy
Zenodo (CERN European Organization for Nuclear Research)·2020· 3 citedOpen Access
Long‐term expanding human airway organoids for disease modeling
The EMBO Journal·2019· 1.0k citedOpen Access
Modelling cancer immunomodulation using epithelial organoid cultures
2018· 7 citedOpen Access
Long-term expanding human airway organoids for disease modelling
2018· 16 citedOpen Access
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Frequent Co-authors

Hans Clevers(20), Sylvia F. Boj(20), Harry Begthel(8), Carla S. Veríssimo(8), Marc van de Wetering(7), Edwin Cuppen(6), Celia Higuera Barón(6), Merel Derksen(5), Farzin Pourfarzad(5), Taya Bezhaeva(5), Johan H. van Es(4), Meritxell Huch(4), Vivian Li(4), Jeroen Korving(4), Andrea Flynn(4), Christopher G. Proud(4), G. Emerens Wensink(4), Mayke Doorn(4), René Overmeer(4), Onno Kranenburg(4)