Jeffrey Hildesheim

National Cancer Institute — United States

Medicine · Health Sciences

14h-index1.4kcitations21works0.02yr avg
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Research Topics

Cancer-related Molecular Pathways(5), Ubiquitin and proteasome pathways(5), Genomics and Chromatin Dynamics(2), Epigenetics and DNA Methylation(2), Cancer Cells and Metastasis(2)

Publications21 total

Therapy-Induced Senescence: Opportunities to Improve Anticancer Therapy
JNCI Journal of the National Cancer Institute·2021· 313 citedOpen Access
Untitled
Oncotarget·2020Open Access
Deconstructing tumor heterogeneity: the stromal perspective
Oncotarget·2020· 41 citedOpen Access
The Role of Lineage Plasticity in Prostate Cancer Therapy Resistance
Clinical Cancer Research·2019· 368 citedOpen Access
Oncogenic senescence: a multi-functional perspective
Oncotarget·2017· 42 citedOpen Access
Neural tube development requires the cooperation of p53‐ and Gadd45a‐associated pathways
Birth Defects Research Part A Clinical and Molecular Teratology·2006· 12 cited
Gadd45a
AfCS-Nature Molecule Pages·2005
Casein Kinase 2- and Protein Kinase A-regulated Adenomatous Polyposis Coli and β-Catenin Cellular Localization Is Dependent on p38 MAPK
Journal of Biological Chemistry·2005· 37 citedOpen Access
The dark side of light: the damaging effects of UV rays and the protective efforts of MAP kinase signaling in the epidermis
DNA repair·2004· 32 cited
p38 Mitogen-Activated Protein Kinase Inhibitor Protects the Epidermis Against the Acute Damaging Effects of Ultraviolet Irradiation by Blocking Apoptosis and Inflammatory Responses
Journal of Investigative Dermatology·2004· 86 citedOpen Access
Gadd45a regulates matrix metalloproteinases by suppressing ΔNp63α and β-catenin via p38 MAP kinase and APC complex activation
Oncogene·2003· 60 cited
Gadd45a protects against UV irradiation-induced skin tumors, and promotes apoptosis and stress signaling via MAPK and p53.
PubMed·2002· 242 cited
Gadd45a: an elusive yet attractive candidate gene in pancreatic cancer.
PubMed·2002· 50 cited
The hSkn-1a POU transcription factor enhances epidermal stratification by promoting keratinocyte proliferation
Journal of Cell Science·2001· 26 cited
Characterization of the Regulatory Domains of the Human Skn-1a/Epoc-1/Oct-11 POU Transcription Factor
Journal of Biological Chemistry·1999· 15 citedOpen Access
Characterization of the functional domains of the human POU transcription factor SKN-1a
Journal of Dermatological Science·1998
alpha1-antitrypsin gene mutation hot spot associated with the formation of a retained and degraded null variant [corrected; erratum to be published].
American Journal of Respiratory Cell and Molecular Biology·1997· 37 cited
Genetic diversity from a limited repertoire of mutations on different common allelic backgrounds: α1-antitrypsin deficiency variant Pduarte
Human Mutation·1993· 15 cited
Comparison of Corneal Epithelial Wound Healing Rates in Scrape vs. Lamellar Keratectomy Injury
Cornea·1990· 11 cited
First isolation step of a plasma factor which enhances lymphocytic cortisol metabolism and which is reduced in cancer patients.
PubMed·1983
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Frequent Co-authors

Albert J. Fornace(8), Richard M. White(3), Peter S. Nelson(3), M. Christine Hollander(3), Judith Campisi(2), Lilit Vardanian(2), Renee E. Vickman(2), Douglas V. Faget(2), Philip A. Beachy(2), David J. Beebe(2), Neil A. Bhowmick(2), Edna Cukierman(2), James G. Granneman(2), Raghu Kalluri(2), Ken S. Lau(2), Ernst Lengyel(2), Joakim Lundeberg(2), Jorge Moscat(2), Kristian Pietras(2), Katerina Politi(2)