Jan Gleixner

German Cancer Research Center — Germany

Biochemistry, Genetics and Molecular Biology · Life Sciences

7h-index584citations18works0.02yr avg
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Research Topics

Single-cell and spatial transcriptomics(8), Cancer-related molecular mechanisms research(4), CRISPR and Genetic Engineering(3), RNA and protein synthesis mechanisms(2), Protein Structure and Dynamics(1)

Publications18 total

Single cell characterization of resistance mechanisms to EGFR-targeted therapy in colorectal cancer patient derived organoids
Zeitschrift für Gastroenterologie·2025
Aged intestinal stem cells propagate cell-intrinsic sources of inflammaging in mice
Developmental Cell·2023· 39 citedOpen Access
Epithelial cells of the intestine acquire cell-intrinsic inflammation signatures during ageing
2021· 2 citedOpen Access
bioFAM/MOFA2: MOFA+ Release
Zenodo (CERN European Organization for Nuclear Research)·2020· 9 citedOpen Access
Robustness and applicability of transcription factor and pathway analysis tools on single-cell RNA-seq data
Genome biology·2020· 340 citedOpen Access
Additional file 3 of Robustness and applicability of transcription factor and pathway analysis tools on single-cell RNA-seq data
Figshare·2020Open Access
Additional file 4 of Robustness and applicability of transcription factor and pathway analysis tools on single-cell RNA-seq data
Figshare·2020Open Access
Additional file 2 of Robustness and applicability of transcription factor and pathway analysis tools on single-cell RNA-seq data
Figshare·2020Open Access
Robustness and applicability of transcription factor and pathway analysis tools on single-cell RNA-seq data
Zenodo (CERN European Organization for Nuclear Research)·2019Open Access
Robustness and applicability of transcription factor and pathway analysis tools on single-cell RNA-seq data
Figshare·2019Open Access
Robustness and applicability of functional genomics tools on scRNA-seq data
2019· 1 citedOpen Access
Prediction of Protein Configurational Entropy (Popcoen)
Journal of Chemical Theory and Computation·2018· 14 cited
Luminopsins integrate opto- and chemogenetics by using physical and biological light sources for opsin activation
Proceedings of the National Academy of Sciences·2016· 115 citedOpen Access
Backbone circularization of <i>Bacillus subtilis</i> family 11 xylanase increases its thermostability and its resistance against aggregation
Molecular BioSystems·2015· 28 cited
Crystal structure of De novo designed ferredoxin-ferredoxin domain insertion protein
2015
BBF RFC 105: The Intein standard - a universal way to modify proteins after translation
DSpace@MIT (Massachusetts Institute of Technology)·2015Open Access
Three-dimensional structure of triclinic form of de novo design insertion domain, Northeast Structural Genomics Consortium (NESG) Target OR327
2013
Venous Thromboembolism and Associated High Plasma Factor VIII Levels:Linked to Cytomegalovirus Infection?
Thrombosis and Haemostasis·2000· 36 cited

Frequent Co-authors

Oliver Stegle(10), Christian H. Holland(7), Jovan Tanevski(7), Javier Perales-Patón(7), Manu P. Kumar(7), Elisabetta Mereu(7), Brian A. Joughin(7), Douglas A. Lauffenburger(7), Holger Heyn(7), Bence Szalai(7), Julio Sáez-Rodríguez(7), Erica Valentini(3), Michael Boutros(3), Maja C. Funk(2), Florian Heigwer(2), Zeynep Gökçe Gayretli Aydın(2), Elena Tonin(2), Jenny Hetzer(2), Danijela Heide(2), Mathias Heikenwälder(2)