Alan Saghatelian

Salk Institute for Biological Studies — United States

Biochemistry, Genetics and Molecular Biology · Life Sciences

77h-index21.8kcitations235works6.22yr avg
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Research Topics

RNA and protein synthesis mechanisms(35), Adipose Tissue and Metabolism(27), Metabolomics and Mass Spectrometry Studies(23), Fatty Acid Research and Health(19), Pancreatic function and diabetes(17)

Publications235 total

Microprotein-Derived Secreted Peptide That Stimulates Cellular cAMP Production
Biochemistry·2026
Translon: a single term for translated regions
Nature Methods·2025· 7 citedOpen Access
Abnormal mitochondrial structure and function in brown adipose tissue of SLC35A4-MP knockout mice
Science Advances·2025· 2 citedOpen Access
CRISPR–Cas9 screening reveals microproteins regulating adipocyte proliferation and lipid metabolism
Proceedings of the National Academy of Sciences·2025· 4 citedOpen Access
ShortStop: a machine learning framework for microprotein discovery
BMC Methods·2025· 1 citedOpen Access
The ERVK3-1 Microprotein Interacts with the HUSH Complex
Biochemistry·2025· 1 citedOpen Access
CRISPR-Cas9 Screening Reveals Microproteins Regulating Adipocyte Proliferation and Lipid Metabolism
2025Open Access
Trifluoroacetate reduces plasma lipid levels and the development of atherosclerosis in mice
2025· 2 citedOpen Access
“Shunt-ing” down obesity with novel endogenous metabolites
Cell Metabolism·2025Open Access
The measurement, regulation and biological activity of FAHFAs
Nature Chemical Biology·2025· 11 citedOpen Access
Identification of microproteins with transactivation activity by polyalanine motif selection
RSC Chemical Biology·2025Open Access
Large-scale proteogenomics characterization of microproteins in Mycobacterium tuberculosis
Scientific Reports·2024· 4 citedOpen Access
Acute inflammation upregulates FAHFAs in adipose tissue and in differentiated adipocytes
Journal of Biological Chemistry·2024· 3 citedOpen Access
Microprotein-encoding RNA regulation in cells treated with pro-inflammatory and pro-fibrotic stimuli
BMC Genomics·2024· 3 citedOpen Access
Dual quorum-sensing control of purine biosynthesis drives pathogenic fitness of <i>Enterococcus faecalis</i>
2024· 4 citedOpen Access
Rp3: Ribosome profiling-assisted proteogenomics improves coverage and confidence during microprotein discovery
Nature Communications·2024· 14 citedOpen Access
Tissue-specific sex-dependent difference in the metabolism of fatty acid esters of hydroxy fatty acids
Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids·2024· 1 citedOpen Access
Time-Restricted Feeding Reduces Atherosclerosis in LDLR KO Mice but Not in ApoE Knockout Mice
Arteriosclerosis Thrombosis and Vascular Biology·2024· 12 citedOpen Access
Presynaptic sensor and silencer of peptidergic transmission reveal neuropeptides as primary transmitters in pontine fear circuit
Cell·2024· 28 citedOpen Access
361-OR: A Multiomics Approach to Identify Genes Important for the Regulation of Antidiabetic and Anti-inflammatory Lipids
Diabetes·2024
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Frequent Co-authors

Benjamin F. Cravatt(12), Jiao Ma(7), Matthew J. Kolar(7), Sarah A. Slavoff(5), Qian Chu(5), Cynthia J. Donaldson(5), Pedro M. Moraes‐Vieira(4), Barbara B. Kahn(4), Bogdan Budnik(4), Ismail Syed(3), Edwin A. Homan(3), Odile D. Peroni(3), Adam G. Schwaid(3), Satchidananda Panda(3), Martina Wallace(3), Christian M. Metallo(3), Reuben J. Shaw(3), M. Reza Ghadiri(3), Christopher Benner(3), Thomas F. Martínez(3)