Sung Hee Hwang

University of Washington — United States

Biochemistry, Genetics and Molecular Biology · Life Sciences

51h-index7.5kcitations275works4.32yr avg
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Research Topics

Eicosanoids and Hypertension Pharmacology(156), Hormonal Regulation and Hypertension(51), Alcohol Consumption and Health Effects(38), Cancer, Hypoxia, and Metabolism(34), Inflammatory mediators and NSAID effects(30)

Publications275 total

Dual acting inhibitor of soluble epoxide hydrolase and Cyclooxygenase-2, attenuates glomerular injury in renal hypoplasia mice
European Journal of Pharmacology·2025
Inhibition of soluble epoxide hydrolase in endotoxin induced pig lung injury
Frontiers in Pharmacology·2025Open Access
Abstract TH167: Soluble Epoxide Hydrolase Inhibition Improves Cerebrovascular Dysfunction And Cognitive Impairments In Aged Diabetic Rats Without Normalizing Blood Glucose
Hypertension·2025
1493P Stratifying late progression risk beyond two years of immunotherapy using methylation-based ctDNA analysis in advanced HCC
Annals of Oncology·2025
Dual Inhibition of sEH and COX-2 Improved Cognition in Alzheimer’s Disease via Enhanced Myogenic Response and Cerebral Artery Distensibility
2025Open Access
Coamorphous Solid Dispersion of a Soluble Epoxide Hydrolase Inhibitor <i>t</i>-TUCB with Amino Acid <scp>l</scp>-Arginine
Organic Process Research & Development·2025· 1 cited
Inhibition of soluble epoxide hydrolase confers neuroprotection and restores microglial homeostasis in a tauopathy mouse model
Molecular Neurodegeneration·2025· 5 citedOpen Access
Correction: Novel inhibition of AKR1C3 and androgen receptor axis by PTUPB synergizes enzalutamide treatment in advanced prostate cancer
Oncogene·2025Open Access
A Soluble Epoxide Hydrolase Inhibitor Improves Cerebrovascular Dysfunction, Neuroinflammation, Amyloid Burden, and Cognitive Impairments in the hAPP/PS1 TgF344-AD Rat Model of Alzheimer’s Disease
International Journal of Molecular Sciences·2025· 6 citedOpen Access
Inhibitors of soluble epoxide hydrolase and cGAS/STING repair defects in amyloid-β clearance underlying vascular complications of Alzheimer's disease
Journal of Alzheimer s Disease·2025· 7 citedOpen Access
Inhibition of Soluble Epoxide Hydrolase Reduces Inflammation and Myocardial Injury in Arrhythmogenic Cardiomyopathy
JACC Basic to Translational Science·2025· 4 citedOpen Access
Inhibition of soluble epoxide hydrolase ameliorates cerebral blood flow autoregulation and cognition in alzheimer's disease and diabetes-related dementia rat models
GeroScience·2025· 11 citedOpen Access
Combining genetics with real-world patient data enables ancestry-specific target identification and drug discovery in Alzheimer’s disease
2025· 1 citedOpen Access
Endocannabinoids facilitate transitory reward engagement through retrograde gain-control
2025· 1 citedOpen Access
Metabolomics reveals soluble epoxide hydrolase as a therapeutic target for high-sucrose diet-mediated gut barrier dysfunction
Proceedings of the National Academy of Sciences·2024· 4 citedOpen Access
Randomized, double‐blind, phase 1a single‐ascending dose and food effect studies assessing safety and pharmacokinetics of EC5026 in healthy volunteers
Clinical and Translational Science·2024· 16 citedOpen Access
Inhibition of Soluble Epoxide Hydrolase Ameliorates Cerebral Blood Flow Autoregulation and Cognition in Alzheimer’s Disease and Diabetes-Related Dementia Rat Models
2024· 2 citedOpen Access
Abstract 3924: Dual COX-2/sEH inhibition enhances immunotherapy and chemotherapy to induce bladder cancer regression
Cancer Research·2024
Inhibition of Soluble Epoxide Hydrolase Reduces Inflammation and Myocardial Injury in Arrhythmogenic Cardiomyopathy
2024· 2 citedOpen Access
Enhancing cancer immunotherapy via inhibition of soluble epoxide hydrolase
Proceedings of the National Academy of Sciences·2024· 24 citedOpen Access
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Frequent Co-authors

Bruce D. Hammock(40), Jun Yang(17), Christophe Morisseau(16), Jun‐Yan Liu(12), Karen Wagner(7), Kin Sing Stephen Lee(6), Guodong Zhang(5), Robert H. Weiss(5), Aaron T. Wecksler(5), Mark W. Kieran(4), Nakcheol Jeong(4), Debin Wan(4), Bora İnceoğlu(4), Nipavan Chiamvimonvat(4), Hiromi I. Wettersten(3), Arzu Ulu(3), Hui‐Hui Yang(3), Jia‐Xi Duan(3), Xinxin Guan(3), Wenjing Zhong(3)