Darryl Pappin

Cold Spring Harbor Laboratory — United States

Chemistry · Physical Sciences

66h-index32.9kcitations188works9.82yr avg
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Research Topics

Advanced Proteomics Techniques and Applications(34), Mass Spectrometry Techniques and Applications(28), DNA Repair Mechanisms(11), Photosynthetic Processes and Mechanisms(10), RNA and protein synthesis mechanisms(9)

Publications188 total

Novel small-molecule inhibitors of the protein kinase DYRK: Potential therapeutic candidates in cancer
2025
Identification and Validation of an inhibitor of the protein kinases PIM and DYRK
2025· 1 citedOpen Access
PTPN23-dependent ESCRT machinery functions as a cell death checkpoint
Nature Communications·2024· 3 citedOpen Access
Dietary pro-oxidant therapy by a vitamin K precursor targets PI 3-kinase VPS34 function
Science·2024· 35 citedOpen Access
TIMP1 is an early biomarker for detection and prognosis of lung cancer
Clinical and Translational Medicine·2023· 31 citedOpen Access
Plasma cells in human pancreatic ductal adenocarcinoma secrete antibodies against self-antigens
JCI Insight·2023· 13 citedOpen Access
Plasma cells in human pancreatic ductal adenocarcinoma secrete antibodies to self-antigens
2023· 2 citedOpen Access
Translesion DNA synthesis polymerase κ is essential to a carcinogen-induced nucleolar stress response
2022· 4 cited
Role of PTP1B in the Regulation of Cholesterol Homeostasis
The FASEB Journal·2022
Unique DNA Polymerase kappa Interactome Suggests Novel Cellular Functions
The FASEB Journal·2022
Single Oligonucleotide Capture of RNA And Temperature Elution Series (SOCRATES) for Identification of RNA-binding Proteins
BIO-PROTOCOL·2022· 1 citedOpen Access
Prostate tumor-induced stromal reprogramming generates Tenascin C that promotes prostate cancer metastasis through YAP/TAZ inhibition
Oncogene·2021· 32 citedOpen Access
Prostate tumor-induced stromal reprogramming generates Tenascin C that promotes prostate cancer metastasis through YAP/TAZ inhibition
2021· 3 citedOpen Access
Oncogenic KRAS engages an RSK1/NF1 pathway to inhibit wild-type RAS signaling in pancreatic cancer
Proceedings of the National Academy of Sciences·2021· 27 citedOpen Access
PHAROH lncRNA regulates Myc translation in hepatocellular carcinoma via sequestering TIAR
eLife·2021· 40 citedOpen Access
Author response: PHAROH lncRNA regulates Myc translation in hepatocellular carcinoma via sequestering TIAR
2021Open Access
PHAROH lncRNA regulates c-Myc translation in hepatocellular carcinoma via sequestering TIAR
2021Open Access
Author Correction: Mito-oncology agent: fermented extract suppresses the Warburg effect, restores oxidative mitochondrial activity, and inhibits in vivo tumor growth
Scientific Reports·2021· 1 citedOpen Access
MaTAR25 lncRNA regulates the Tensin1 gene to impact breast cancer progression
Nature Communications·2020· 99 citedOpen Access
Characterization of Peptide Activators of Protein Tyrosine Phosphatase 1B
Free Radical Biology and Medicine·2020
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Frequent Co-authors

Benito Cañas(7), Keith Rivera(5), Rosamonde E. Banks(4), Michael J. Dünn(4), Peter J. Selby(4), John S. Cottrell(3), Philip L. Ross(3), Michael Bartlet‐Jones(3), Iok In Christine Chio(3), Hervé Tiriac(3), Kevin Wright(3), Youngkyu Park(3), David A. Tuveson(3), Dinah Rahman(3), Graham Warren(3), Cathérine Rabouille(3), Paul S. Freemont(3), D. Rahman(3), Peter Robins(3), B. Williamson(2)