David A. Tuveson

Cold Spring Harbor Laboratory — United States

Medicine · Health Sciences

112h-index84.2kcitations893works3.72yr avg
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Research Topics

Pancreatic and Hepatic Oncology Research(408), Cancer Genomics and Diagnostics(190), Cancer Cells and Metastasis(138), Cancer Research and Treatments(90), Epigenetics and DNA Methylation(88)

Publications891 total

AUM-302, a novel triple PIM/PI3K/mTOR inhibitor, synergizes with RAS inhibition and impedes the growth of pancreatic ductal adenocarcinoma spheroids and organoids
Frontiers in Pharmacology·2026Open Access
Robust ancestry inference from challenging human molecular data with RAIDS
Zenodo (CERN European Organization for Nuclear Research)·2026Open Access
Robust ancestry inference from challenging human molecular data with RAIDS
Zenodo (CERN European Organization for Nuclear Research)·2026Open Access
Frizzled 6 Drives EMT and Stromal Remodeling Downstream of SP1 in Basal-like Pancreatic Cancer
2026Open Access
Supplementary Figure S1-S11 and Table S1 from Splicing Factor SRSF1 Promotes Pancreatitis and KRAS<sup>G12D</sup>-Mediated Pancreatic Cancer
2025Open Access
Supplementary Table 19 from Genetic Ancestry Inference from Cancer-Derived Molecular Data across Genomic and Transcriptomic Platforms
2025Open Access
Supplementary Material from Genetic Ancestry Inference from Cancer-Derived Molecular Data across Genomic and Transcriptomic Platforms
2025Open Access
Development of Dual Targeting Radiotheranostics for Pancreatic Ductal Adenocarcinoma
Nuclear Medicine and Biology·2025
Investigating the roles of GLI transcription factors in the pancreatic cancer microenvironment 4554
The Journal of Immunology·2025
Click chemistry for natural product-inspired covalent drug discovery
Drug Discovery Today·2025Open Access
Abstract B102: A model for the origins of transcriptional heterogeneity in human pancreatic ductal adenocarcinoma
Cancer Research·2025
Abstract B081: Association between clonal hematopoiesis and survival outcomes in pancreatic ductal adenocarcinoma: Analysis from the PASS-01 trial
Cancer Research·2025
Abstract B086: External validation of a multimodal machine learning system to predict outcomes in advanced pancreatic cancer in the PASS-01 trial
Cancer Research·2025
Erratum: PASS-01: Randomized Phase II Trial of Modified FOLFIRINOX Versus Gemcitabine/Nab-Paclitaxel and Molecular Correlatives for Previously Untreated Metastatic Pancreatic Cancer
Journal of Clinical Oncology·2025· 1 cited
PASS-01: Randomized Phase II Trial of Modified FOLFIRINOX Versus Gemcitabine/Nab-Paclitaxel and Molecular Correlatives for Previously Untreated Metastatic Pancreatic Cancer
Journal of Clinical Oncology·2025· 7 citedOpen Access
MYC-Driven Activation of USP39 Enhances SRSF1 Stability and Promotes PDAC Progression
2025Open Access
Signal peptide–independent secretion of keratin-19 by pancreatic cancer cells
Proceedings of the National Academy of Sciences·2025· 3 citedOpen Access
Targeting Neutrophil Extracellular Traps to inhibit Colon Cancer Tumor Necrosis and Metastasis
2025· 1 citedOpen Access
Supplementary Figure S6 from FGFR2 Abrogation Intercepts Pancreatic Ductal Adenocarcinoma Development
2025Open Access
Supplementary Figure S8 from FGFR2 Abrogation Intercepts Pancreatic Ductal Adenocarcinoma Development
2025Open Access
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Frequent Co-authors

Sunil R. Hingorani(8), Christine Feig(8), Ralph H. Hruban(8), Tyler Jacks(8), Michael A. Jacobetz(6), Hervé Tiriac(6), Dannielle D. Engle(6), Hans Clevers(6), Youngkyu Park(6), Douglas T. Fearon(5), Giulia Biffi(5), Ela Elyada(5), Roderick T. Bronson(5), Denise Crowley(5), Albrecht Neeße(5), George D. Demetri(4), Kenneth P. Olive(4), Aarthi Gopinathan(4), Christine A. Iacobuzio–Donahue(4), Daniel Öhlund(4)