Francis X. Farrell

Carilion Clinic — United States

Medicine · Health Sciences

30h-index3.3kcitations55works0.02yr avg
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Research Topics

Erythropoietin and Anemia Treatment(16), Protein Kinase Regulation and GTPase Signaling(5), Interstitial Lung Diseases and Idiopathic Pulmonary Fibrosis(5), COVID-19 Clinical Research Studies(4), TGF-β signaling in diseases(4)

Publications53 total

Risk factors and titers of COVID-19 infection in a longitudinal statewide seroepidemiology cohort
BMC Infectious Diseases·2023· 3 citedOpen Access
Risk factors for COVID-19 infection in a longitudinal statewide seroepidemiology cohort
Research Square (Research Square)·2022Open Access
Assessment of Seroprevalence of SARS-CoV-2 and Risk Factors Associated With COVID-19 Infection Among Outpatients in Virginia
JAMA Network Open·2021· 51 citedOpen Access
Adenosine Signaling Increases Proinflammatory and Profibrotic Mediators through Activation of a Functional Adenosine 2B Receptor in Renal Fibroblasts.
PubMed·2016· 30 cited
Macrophage-derived tumor necrosis factor-α mediates diabetic renal injury
Kidney International·2015· 190 citedOpen Access
Serum Inflammatory and Immune Mediators Are Elevated in Early Stage Diabetic Nephropathy.
PubMed·2015· 89 cited
Neutralization of IL‐13Ra1 receptor on Human CD4+ CD45RO+ Memory T cells Stimulates Release of IL‐17
The FASEB Journal·2012
Proinflammatory/Profibrotic Effects of Interleukin-17A on Human Proximal Tubule Epithelium
Nephron Experimental Nephrology·2010· 27 cited
Development of cell-based immunoassays to measure type I collagen in cultured fibroblasts
The International Journal of Biochemistry & Cell Biology·2010· 5 cited
Interleukin-1± Pulmonary Pro-Inflammatory / Pro-Fibrotic Activity
2010
Pro‐inflammatory / Pro‐fibrotic effects of Interleukin‐17A on human proximal tubule epithelium
The FASEB Journal·2009
Generation of bleomycin-induced lung fibrosis is independent of IL-16
Cytokine·2009· 6 cited
BMP-7 Does Not Protect against Bleomycin-Induced Lung or Skin Fibrosis
PLoS ONE·2008· 62 citedOpen Access
BMP-7 fails to attenuate TGF- 1-induced epithelial-to-mesenchymal transition in human proximal tubule epithelial cells
Nephrology Dialysis Transplantation·2008· 52 cited
Hyper-responsiveness of IPF/UIP fibroblasts: Interplay between TGFβ1, IL-13 and CCL2
The International Journal of Biochemistry & Cell Biology·2008· 147 cited
Expression and characterization of a human BMP-7 variant with improved biochemical properties
Protein Expression and Purification·2007· 40 cited
Erythropoietin for the Treatment of Acute Ischemic Stroke: Preclinical Rationale
2006
Peptide mimetics of erythropoietin are powerful probes of receptor activation mechanisms
Kluwer Academic Publishers eBooks·2006· 1 cited
Recombinant epoetins do not stimulate tumor growth in erythropoietin receptor–positive breast carcinoma models
Molecular Cancer Therapeutics·2006· 81 citedOpen Access
Potential involvement of BMP receptor type IB activation in a synergistic effect of chondrogenic promotion between rhTGFβ3 and rhGDF5 or rhBMP7 in human mesenchymal stem cells
Growth Factors·2006· 31 cited
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Frequent Co-authors

Linda K. Jolliffe(16), Jennifer Tullai(10), Francis P. Barbone(8), Dana L. Johnson(8), Frank J. McMahon(7), Oded Livnah(5), Ian A. Wilson(5), Patrick Wilkinson(5), Ze’ev Gechtman(5), Nicholas C. Wrighton(4), Linda S. Mulcahy(4), William J. Dower(4), E.A. Stura(4), Rochelle L. Argentieri(4), Steven A. Middleton(4), Kenneth R. LaMontagne(4), Jeannene Butler(4), Paul L. Dudas(4), E G Lapetina(4), Lynne A. Murray(3)