Liam J. McGuffin

University of Reading — United Kingdom

Biochemistry, Genetics and Molecular Biology · Life Sciences

41h-index12.2kcitations105works7.22yr avg
OpenAlex↗ORCID↗Google Scholar↗Lab page↗

Accepting Students?

No reports yet. Know if this professor is taking students?

Research Topics

Protein Structure and Dynamics(59), Enzyme Structure and Function(36), Machine Learning in Bioinformatics(25), RNA and protein synthesis mechanisms(19), Genomics and Phylogenetic Studies(15)

Publications103 total

Pathogenesis of Noonan Syndrome is Modulated by NOC2L, a Novel Interactor of LZTR1 Leading to Impaired P53 Signalling
The Journal of Clinical Endocrinology & Metabolism·2025Open Access
Highlights of Model Quality Assessment in <scp>CASP16</scp>
Proteins Structure Function and Bioinformatics·2025Open Access
Prediction and quality assessment of protein quaternary structure models using the MultiFOLD2 and ModFOLDdock2 servers
Nucleic Acids Research·2025· 9 citedOpen Access
The pathogenesis of Noonan syndrome is modulated by NOC2L, a novel interactor of LZTR1 leading to impaired p53 signalling
2025Open Access
Inter-platelet communication driving thrombus formation is regulated by extracellular calpain-1 cleavage of connexin 62
Haematologica·2025Open Access
Beyond AlphaFold2: The Impact of AI for the Further Improvement of Protein Structure Prediction
Methods in molecular biology·2024· 20 cited
QSOX2 Deficiency-induced short stature, gastrointestinal dysmotility and immune dysfunction
Nature Communications·2024· 7 citedOpen Access
A novel human disorder: QSOX2 deficiency-induced growth restriction, gastrointestinal dysmotility and immune dysfunction highlights a new mechanism of disease
Endocrine Abstracts·2024
Benchmarking of AlphaFold2 accuracy self-estimates as indicators of empirical model quality and ranking: a comparison with independent model quality assessment programmes
Bioinformatics·2024· 18 citedOpen Access
ModFOLD9: A Web Server for Independent Estimates of 3D Protein Model Quality
Journal of Molecular Biology·2024· 18 citedOpen Access
Benchmarking of AlphaFold2 accuracy self-estimates as empirical quality measures and model ranking indicators and their comparison with independent model quality assessment programs
2023· 1 citedOpen Access
Are the integrin binding motifs within SARS CoV-2 spike protein and MHC class II alleles playing the key role in COVID-19?
Frontiers in Immunology·2023· 5 citedOpen Access
Estimation of model accuracy in <scp>CASP15</scp> using the M<scp>odFOLDdock</scp> server
Proteins Structure Function and Bioinformatics·2023· 24 citedOpen Access
CAID prediction portal: a comprehensive service for predicting intrinsic disorder and binding regions in proteins
Nucleic Acids Research·2023· 55 citedOpen Access
Prediction of protein structures, functions and interactions using the IntFOLD7, MultiFOLD and ModFOLDdock servers
Nucleic Acids Research·2023· 74 citedOpen Access
Estimation of Model Accuracy in CASP15 Using the ModFOLDdock Server
2023· 4 citedOpen Access
Using Local Protein Model Quality Estimates to Guide a Molecular Dynamics-Based Refinement Strategy
Methods in molecular biology·2023· 1 cited
Improvement of protein tertiary and quaternary structure predictions using the ReFOLD refinement method and the AlphaFold2 recycling process
Bioinformatics Advances·2023· 19 citedOpen Access
Quality Estimates for 3D Protein Models
Methods in molecular biology·2023· 1 citedOpen Access
Machine Learning Methods for Predicting Protein Contacts
WORLD SCIENTIFIC eBooks·2022
page 1 of 6Next →

Frequent Co-authors

David T. Jones(14), Daniel B. Roche(11), Kevin Bryson(6), Jonathan J. Ward(5), Ali H. A. Maghrabi(5), Maria T. Buenavista(5), Jaspreet Singh Sodhi(4), Recep Adiyaman(4), Ahmad Nazrun Shuid(4), Bernard F. Buxton(3), Jennifer Atkins(3), Bajuna R. Salehe(3), Björn Wallner(3), Timothy A. Burgis(2), Laurence V. Bindschedler(2), Rainer Cramer(2), Pietro D. Spanu(2), Danielle A Brackenridge(2), John O. Nealon(2), Stuart Tetchner(2)