Sucheol Gil

Biochemistry, Genetics and Molecular Biology · Life Sciences

20h-index1.1kcitations38works6.02yr avg
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Research Topics

Virus-based gene therapy research(20), CRISPR and Genetic Engineering(12), RNA Interference and Gene Delivery(9), CAR-T cell therapy research(6), Hemoglobinopathies and Related Disorders(5)

Publications38 total

In vivo HSC gene therapy enables sustained eCD4-Ig expression for SIV prevention
Molecular Therapy Advances·2026Open Access
Introducing a hemoglobin G-Makassar variant in HSCs by in vivo base editing treats sickle cell disease in mice
Molecular Therapy·2024· 12 citedOpen Access
HDAd6/35++ - A new helper-dependent adenovirus vector platform for in vivo transduction of hematopoietic stem cells
Molecular Therapy — Methods & Clinical Development·2023· 20 citedOpen Access
Stable HIV decoy receptor expression after in vivo HSC transduction in mice and NHPs: Safety and efficacy in protection from SHIV
Molecular Therapy·2023· 1 citedOpen Access
<i>In vivo</i> HSC prime editing rescues Sickle Cell Disease in a mouse model
Blood·2023· 68 citedOpen Access
Stable HIV decoy receptor expression after in vivo HSC transduction in mice and NHPs: Safety and efficacy in protection from SHIV
Molecular Therapy·2023· 5 citedOpen Access
In vivo base editing by a single i.v. vector injection for treatment of hemoglobinopathies
JCI Insight·2022· 36 citedOpen Access
In vivo HSC transduction in rhesus macaques with an HDAd5/3<b>+</b> vector targeting desmoglein 2 and transiently overexpressing cxcr4
Blood Advances·2022· 29 citedOpen Access
Safe and efficient in vivo hematopoietic stem cell transduction in nonhuman primates using HDAd5/35++ vectors
Molecular Therapy — Methods & Clinical Development·2022· 1 citedOpen Access
Translational development of a tumor junction opening technology
Scientific Reports·2022· 7 citedOpen Access
<i>In Vivo</i> Hematopoietic Stem Cell Gene Therapy for SARS-CoV2 Infection Using a Decoy Receptor
Human Gene Therapy·2022· 10 citedOpen Access
Safe and efficient in vivo hematopoietic stem cell transduction in nonhuman primates using HDAd5/35++ vectors
Molecular Therapy — Methods & Clinical Development·2021· 43 citedOpen Access
Translational Development of A Tumor Junction Opening Technology
Research Square (Research Square)·2021Open Access
Persistent Control of SIV Infection in Rhesus Macaques By Expressing a Highly Potent SIV Decoy Receptor after <i>In Vivo</i> HSC Transduction
Blood·2021· 2 cited
Single-dose MGTA-145/plerixafor leads to efficient mobilization and in vivo transduction of HSCs with thalassemia correction in mice
Blood Advances·2021· 20 citedOpen Access
In vivo HSPC gene therapy with base editors allows for efficient reactivation of fetal γ-globin in β-YAC mice
Blood Advances·2021· 87 citedOpen Access
<i>In Vivo</i> HSC Gene Therapy with Base Editors Allows for Efficient Reactivation of Fetal Globin in Beta-Yac Mice
Blood·2020· 1 cited
<i>In Vivo</i> HSC Gene Therapy for Hemoglobinopathies: A Proof of Concept Evaluation in Rhesus Macaques
Blood·2020· 12 cited
Mgta-145 / Plerixafor-Mediated HSC Mobilization and Intravenous HDAd5/35++ Vector Injection into Mice Allows for Efficient In Vivo HSC Transduction and Stable Gene Marking in Peripheral Blood Cells of CD46-Transgenic and Thalassemia Mice
Blood·2020
In Vivo HSC Gene Therapy Using a Bi-modular HDAd5/35++ Vector Cures Sickle Cell Disease in a Mouse Model
Molecular Therapy·2020· 68 citedOpen Access
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Frequent Co-authors

André Lieber(25), Hongjie Wang(15), Hans‐Peter Kiem(13), Chang Li(11), Aphrodite Georgakopoulou(10), Evangelia Yannaki(9), Jiho Kim(9), Audrey Germond(9), Chang Li(8), Thalia Papayannopoulou(8), Audrey Baldessari(7), Anna Kate Anderson(6), Richard J. Lamont(5), Zhinan Liu(5), Gustavo Matute‐Bello(5), Amit Pande(4), Zsuzsanna Izsvák(4), Donald R. Demuth(3), R. David Hawkins(3), Hongjie Wang(3)