Spyros A. Kalams

Vanderbilt University — United States

Immunology and Microbiology · Life Sciences

57h-index15.7kcitations226works2.62yr avg
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Research Topics

HIV Research and Treatment(134), Immune Cell Function and Interaction(104), T-cell and B-cell Immunology(58), HIV/AIDS drug development and treatment(22), Cytomegalovirus and herpesvirus research(22)

Publications221 total

CD8+ T cells cross-restricted by HLA-B*57 and HLA-E*01 recognize HIV Gag with different functional profiles
JCI Insight·2025Open Access
Glycan-reactive antibodies isolated from human HIV-1 vaccine trial participants show broad pathogen cross-reactivity
Journal of Virology·2025Open Access
Mapping CMV-related immune signatures in blood, aorta and perivascular mediastinal adipose tissue
Philosophical Transactions of the Royal Society B Biological Sciences·2025· 1 citedOpen Access
The impact of aging on adaptive immune responses to improved licensed influenza vaccines 4708
The Journal of Immunology·2025Open Access
SGLT2 inhibitors modulate inflammation by altering macrophage metabolism and decreasing monocyte platelet aggregates 3256
The Journal of Immunology·2025Open Access
SUN-559 Empagliflozin Reduces Monocyte-Platelet Aggregates: A Link to Cardiometabolic Benefits
Journal of the Endocrine Society·2025Open Access
Cross-Reactive Serologic Responses Arise after Early Post-Transplant Influenza Immunization
American Journal of Transplantation·2025Open Access
Safety of Alternative Influenza Vaccination Strategies in Adult Solid Organ Transplant Recipients
American Journal of Transplantation·2025
Adaptive-like NK cell responses to influenza correlate with humoral immunity and are influenced by age and sex
2025Open Access
Safety, pharmacokinetics, and neutralisation activity of PGDM1400LS, a V2 specific HIV-1 broadly neutralising antibody, infused intravenously or subcutaneously in people without HIV-1 in the USA (HVTN 140/HPTN 101 part A): a first-in-human, phase 1 randomised trial
The Lancet HIV·2025· 3 cited
Antiviral CD4 <sup>+</sup> T and myeloid cell responses to influenza vaccines are attenuated in older adults
2025· 1 citedOpen Access
Single-cell immune profiling at time of <i>M. tuberculosis</i> exposure reveals antigen-reactive programs that predict progression to active disease
2025Open Access
Genome-wide association study in Brazil identifies genetic susceptibility to tuberculosis with single-cell gene expression effects
2025· 1 citedOpen Access
CD3+ T-cell: CD14+ monocyte complexes are dynamic and increased with HIV and glucose intolerance
The Journal of Immunology·2025· 1 citedOpen Access
HIV-1 adapts to HLA class II–associated selection pressure exerted by CD4 <sup>+</sup> and CD8 <sup>+</sup> T cells
Science Advances·2025· 3 citedOpen Access
Glycan-reactive antibodies isolated from human HIV-1 vaccine trial participants show broad pathogen cross-reactivity
2025Open Access
Safety, Pharmacokinetics, and Neutralization Activity of PGDM1400LS, VRC07-523-LS, and PGT121.414.LS Infused Intravenously or Subcutaneously: A Phase 1 Randomized Trial (HVTN 140/HPTN 101 Part B)
SSRN Electronic Journal·2025Open Access
Multiomic single-cell sequencing defines tissue-specific responses in Stevens-Johnson syndrome and toxic epidermal necrolysis
Nature Communications·2024· 22 citedOpen Access
Omicron COVID-19 immune correlates analysis of a third dose of mRNA-1273 in the COVE trial
UNC Libraries·2024Open Access
SUN-239 SGLT2 Inhibitors Modulate the Immune Cell Metabolic Profile
Journal of the Endocrine Society·2024Open Access
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Frequent Co-authors

Bruce D. Walker(29), Alicja Trocha(12), Eric Rosenberg(9), Christian Brander(9), Susan Buchbinder(8), R. Paul Johnson(8), Philip Goulder(8), Marcus Altfeld(8), Lindsey R. Baden(7), Otto O. Yang(7), David C. Montefiori(5), Marylyn M. Addo(5), Marnie Elizaga(5), John Hural(5), Kelly E. Hartman(5), Richard A. Koup(4), Norman G. Jones(4), Robert L. Eldridge(4), Georgia D. Tomaras(4), William A. Blattner(4)