Clifford W. Shults

Columbia University Irving Medical Center — United States

Medicine · Health Sciences

46h-index10.2kcitations96works0.02yr avg
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Research Topics

Parkinson's Disease Mechanisms and Treatments(37), Neurological disorders and treatments(17), Coenzyme Q10 studies and effects(17), Nuclear Receptors and Signaling(17), Genetic Neurodegenerative Diseases(15)

Publications95 total

Natural history study of MSA in North America: A prospective cohort study
Autonomic Neuroscience·2015· 1 cited
Natural history of multiple system atrophy in the USA: a prospective cohort study
The Lancet Neurology·2015· 318 citedOpen Access
Platelet mitochondrial activity and pesticide exposure in early Parkinson's disease
Movement Disorders·2015· 17 citedOpen Access
Prospective Differentiation of Multiple System Atrophy From Parkinson Disease, With and Without Autonomic Failure
Archives of Neurology·2009· 155 citedOpen Access
Dopamine Depletion Induces Distinct Compensatory Gene Expression Changes in DARPP-32 Signal Transduction Cascades of Striatonigral and Striatopallidal Neurons
Journal of Neuroscience·2009· 29 citedOpen Access
Dopamine depletion induced up-regulation of HCN3 enhances rebound excitability of basal ganglia output neurons
Neurobiology of Disease·2009· 13 citedOpen Access
Rifampicin reduces α-synuclein in a transgenic mouse model of multiple system atrophy
Neuroreport·2008· 74 citedOpen Access
Potential outcome measures and trial design issues for multiple system atrophy Members of “The North American Multiple System Atrophy Study Group” are listed as an Appendix .
2007
Potential outcome measures and trial design issues for multiple system atrophy
Movement Disorders·2007· 63 citedOpen Access
Calf venous compliance in multiple system atrophy
American Journal of Physiology-Heart and Circulatory Physiology·2007· 11 cited
G2019S mutation in the leucine‐rich repeat kinase 2 gene is not associated with multiple system atrophy
Movement Disorders·2007· 37 citedOpen Access
R1514Q substitution in Lrrk2 is not a pathogenic Parkinson's disease mutation
Movement Disorders·2006· 8 cited
Mutations in LRRK2 other than G2019S are rare in a north american–based sample of familial Parkinson's disease
Movement Disorders·2006· 32 cited
Mutations in DJ-1 are rare in familial Parkinson disease
Neuroscience Letters·2006· 55 citedOpen Access
α-Synuclein from platelets is not phosphorylated at serine 129 in Parkinson's disease and multiple system atrophy
Neuroscience Letters·2006· 15 cited
Lewy bodies
Proceedings of the National Academy of Sciences·2006· 472 citedOpen Access
Neurological and Neurodegenerative Alterations in a Transgenic Mouse Model Expressing Human α-Synuclein under Oligodendrocyte Promoter: Implications for Multiple System Atrophy
Journal of Neuroscience·2005· 254 citedOpen Access
The North American Multiple System Atrophy Study Group
Journal of Neural Transmission·2005· 86 citedOpen Access
Presence of an APOE4 allele results in significantly earlier onset of Parkinson's disease and a higher risk with dementia
Movement Disorders·2005· 123 cited
Reexamination of the TEMPO Study
Archives of Neurology·2005· 4 cited
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Frequent Co-authors

Thomas L. O’Donohue(7), Fred H. Gage(6), Richard Haas(6), Thomas N. Chase(6), Eliezer Masliah(5), Tatiana Foroud(5), Sid Gilman(4), Edward Rockenstein(4), David Song(4), William C. Nichols(4), Nathan Pankratz(4), Alice Rudolph(4), Phillip A. Low(4), Paola Sandroni(4), Kyoko Tsuboi(4), Cheryl Halter(3), Caroline M. Tanner(3), Rémi Quirion(3), M. Flint Beal(3), Cinda J. Helke(3)