Nancy N. Fang

University of British Columbia — Canada

Biochemistry, Genetics and Molecular Biology · Life Sciences

9h-index624citations15works0.02yr avg
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Research Topics

Ubiquitin and proteasome pathways(11), Endoplasmic Reticulum Stress and Disease(8), Fungal and yeast genetics research(3), Autophagy in Disease and Therapy(3), 14-3-3 protein interactions(3)

Publications15 total

A direct role for a mitochondrial targeting sequence in signalling stress
Nature·2025Open Access
Elucidation of the 14-3-3ζ interactome reveals critical roles of RNA-splicing factors during adipogenesis
Journal of Biological Chemistry·2018· 26 citedOpen Access
Identification of Novel Adipogenic Factors in the 14–3-3ζ Interactome During Adipocyte Differentiation
Canadian Journal of Diabetes·2017
Elucidation of the 14-3-3ζ interactome reveals critical roles of RNA splicing factors during adipogenesis
2017Open Access
Deubiquitinase activity is required for the proteasomal degradation of misfolded cytosolic proteins upon heat-stress
Nature Communications·2016· 66 citedOpen Access
A Role for the Budding Yeast Separase, Esp1, in Ty1 Element Retrotransposition
PLoS Genetics·2015· 17 citedOpen Access
Project connect: Public health partnerships to prevent violence against women
7th Biennial National Conference on Health and Domestic Violence·2015
Rsp5/Nedd4 is the main ubiquitin ligase that targets cytosolic misfolded proteins following heat stress
Nature Cell Biology·2014· 190 citedOpen Access
Polarization of the Endoplasmic Reticulum by ER-Septin Tethering
Cell·2014· 107 citedOpen Access
Heat‐induced degrons and the co‐chaperone Ydj1‐adaptor mediate the ubiquitination of misfolded proteins by the Rsp5 ubiquitin ligase upon stress (558.1)
The FASEB Journal·2014
Systems-Wide Analysis of Protein Ubiquitylation: We Finally Have the Tiger by the Tail
2014
System-wide Analysis Reveals Intrinsically Disordered Proteins Are Prone to Ubiquitylation after Misfolding Stress
Molecular & Cellular Proteomics·2013· 23 citedOpen Access
Hul5 ubiquitin ligase
Prion·2012· 12 citedOpen Access
The Yeast Ubr1 Ubiquitin Ligase Participates in a Prominent Pathway That Targets Cytosolic Thermosensitive Mutants for Degradation
G3 Genes Genomes Genetics·2012· 39 citedOpen Access
Hul5 HECT ubiquitin ligase plays a major role in the ubiquitylation and turnover of cytosolic misfolded proteins
Nature Cell Biology·2011· 144 citedOpen Access

Frequent Co-authors

Thibault Mayor(14), Sophie A. Comyn(3), Alex H. M. Ng(3), Yves Mugabo(3), Gareth E. Lim(3), Mang Zhu(2), Vivien Measday(2), Barry P. Young(2), Christopher Loewen(2), Mina Sadeghi(2), Gerard T. Chan(1), Avinash K. Persaud(1), Raymond J. Deshaies(1), Daniela Rotin(1), Joerg Gsponer(1), Jesse T. Chao(1), Andrew K. Wong(1), Shabnam Tavassoli(1), Adam Chruscicki(1), LeAnn J. Howe(1)