Thomas Balle

Novozymes (Denmark) — Denmark

Biochemistry, Genetics and Molecular Biology · Life Sciences

28h-index2.5kcitations121works0.32yr avg
OpenAlex↗ORCID↗Google Scholar↗Lab page↗

Accepting Students?

No reports yet. Know if this professor is taking students?

Research Topics

Nicotinic Acetylcholine Receptors Study(57), Receptor Mechanisms and Signaling(46), Neuroscience and Neuropharmacology Research(22), Cholinesterase and Neurodegenerative Diseases(20), Computational Drug Discovery Methods(18)

Publications121 total

Genetic Variations in the P2X7 Receptor: Opportunities and Challenges for Drug Development
International Journal of Molecular Sciences·2025· 1 citedOpen Access
A Pharmacophore for Drugs Targeting the α4α4 Binding Site of the (α4) <sub>3</sub> (β2) <sub>2</sub> Nicotinic Acetylcholine Receptor
Journal of Neurochemistry·2025Open Access
Preparation of Cello-Oligosaccharides by Precise-Controlled Enzymatic Depolymerization and Its Amphiphilic Functionalization for High-Oil Load Emulsification
Journal of Agricultural and Food Chemistry·2025
Deep learning structural insights into heterotrimeric alternatively spliced P2X7 receptors
Purinergic Signalling·2023· 1 citedOpen Access
The Anti-Nociceptive Effects of Nicotine in Humans: A Systematic Review and Meta-Analysis
Pharmaceuticals·2023· 9 citedOpen Access
Structural insights into the heterotrimeric alternatively spliced P2X7 receptors
2023Open Access
Combination of High-Resolution Structures for the B Cell Receptor and Co-Receptors Provides an Understanding of Their Interactions with Therapeutic Antibodies
Cancers·2023· 6 citedOpen Access
Binding and Dynamics Demonstrate the Destabilization of Ligand Binding for the S688Y Mutation in the NMDA Receptor GluN1 Subunit
Molecules·2023· 3 citedOpen Access
Biosynthesis of pectic oligosaccharide-based amphiphiles as novel stabilizers of nanoemulsions by coupling enzymatic depolymerization with alkyl/alkenyl succinylation
Food Hydrocolloids·2023· 4 citedOpen Access
Design of concatenated ion channels using AlphaFold2: A new era?
Biophysical Journal·2023Open Access
Computer-Aided Drug Design towards New Psychotropic and Neurological Drugs
Molecules·2023· 37 citedOpen Access
GABA<sub>A</sub> receptors as targets for anaesthetics and analgesics and promising candidates to help treat coronavirus infections: A mini‐review
Basic & Clinical Pharmacology & Toxicology·2022· 19 citedOpen Access
Binding and dynamics demonstrate the destabilisation of ligand binding for the S688Y mutation in the NMDA receptor GluN1 subunit
Research Square (Research Square)·2022Open Access
Alternatively Spliced Isoforms of the P2X7 Receptor: Structure, Function and Disease Associations
International Journal of Molecular Sciences·2022· 30 citedOpen Access
Synthetic Sansanmycin Analogues as Potent <i>Mycobacterium tuberculosis</i> Translocase I Inhibitors
Journal of Medicinal Chemistry·2021· 15 cited
Novel methyllycaconitine analogues selective for the α4β2 over α7 nicotinic acetylcholine receptors
Bioorganic & Medicinal Chemistry·2021· 7 citedOpen Access
CardioTox net: a robust predictor for hERG channel blockade based on deep learning meta-feature ensembles
Journal of Cheminformatics·2021· 63 citedOpen Access
Effects of mutations in the NMDA receptor GluN1 subunit on binding and dynamics: a computational approach
Acta Crystallographica Section A Foundations and Advances·2021
Delta-containing GABAA receptors in pain management: Promising targets for novel analgesics
Neuropharmacology·2021· 17 cited
Quantitative Toxicity Prediction via Meta Ensembling of Multitask Deep Learning Models
ACS Omega·2021· 39 citedOpen Access
page 1 of 7Next →

Frequent Co-authors

Philip K. Ahring(15), Mary Chebib(10), Michael Gajhede(9), J.S. Kastrup(9), Anders A. Jensen(7), Kasper Harpsøe(6), Dan Peters(6), Tommy Sander(6), Bente Frølund(6), Tommy Liljefors(5), Jesper L. Kristensen(5), Elsebet Ø. Nielsen(5), Jeppe A. Olsen(5), Azadeh Shahsavar(4), Dinesh C. Indurthi(4), Paolo Tosco(3), Marianne L. Jensen(3), Rikke Bergmann(3), Natalia M. Kowal(3), Vivian W. Y. Liao(3)