Sonya A. MacParland

University Health Network — Canada

Biochemistry, Genetics and Molecular Biology · Life Sciences

28h-index5.5kcitations123works6.52yr avg
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Research Topics

Single-cell and spatial transcriptomics(27), Hepatitis C virus research(23), Liver Disease Diagnosis and Treatment(21), Liver physiology and pathology(14), Hepatitis B Virus Studies(13)

Publications121 total

High-resolution spatial transcriptomics of adult and pediatric human liver with Visium HD
2026Open Access
NINJ1 mediates hepatic ischemia-reperfusion injury
2026Open Access
Author Correction: Towards a reference cell atlas of liver diversity over the human lifespan
Nature Reviews Gastroenterology & Hepatology·2025Open Access
Towards a reference cell atlas of liver diversity over the human lifespan
Nature Reviews Gastroenterology & Hepatology·2025
Single-cell atlas of human pediatric liver reveals age-related hepatic gene signatures
Hepatology Communications·2025· 3 citedOpen Access
Kupffer cells are essential for platelet-mediated thrombopoietin generation in the liver
Proceedings of the National Academy of Sciences·2025· 3 citedOpen Access
Interleukin-4-mediated Pro-Regenerative Cellular Reprogramming in 3-dimensional Liver Culture
Cellular and Molecular Gastroenterology and Hepatology·2025Open Access
Claudin-1 is a mediator and therapeutic target in primary sclerosing cholangitis
Journal of Hepatology·2025· 2 citedOpen Access
Virus-Inclusive Single-Cell RNA Sequencing Reveals Broad Cellular Tropism and Common Pathway Dysfunctions Linked to Cytomegalovirus Infection in Organ Transplant Recipients
American Journal of Transplantation·2025· 1 cited
QuPath Stain Quantification of Whole Tissue by Percent Area v1
2025Open Access
Decoding the PSC fibrotic niche: Hepatocyte stress and metallothioneins
Hepatology·2025
Scalable expansion and hepatic zone maturation of hepatic progenitor cells from human pluripotent stem cells
2025
No Evidence of Anti-Influenza Nucleoprotein Antibodies in Retail Milk from Across Canada (April–July 2024)
Viral Immunology·2025
OS-056 Integrative spatial proteomics and transcriptomics of patient liver tissues unravel Claudin-1 as a mediator and therapeutic target for primary sclerosing cholangitis
Journal of Hepatology·2025
A Single-Cell Atlas Of Human Pediatric Liver Reveals Age-Related Hepatic Gene Signatures
2025· 2 citedOpen Access
A single-nucleus and spatial transcriptomic atlas of the COVID-19 liver reveals topological, functional, and regenerative organ disruption in patients
Genome biology·2025· 6 citedOpen Access
A Single-Cell Woodchuck Liver Atlas Identifies Healthy and Disease-related Cellular Programs Conserved in Human
2025
No Evidence of Anti-influenza Nucleoprotein Antibodies in Retail Milk from Across Canada (April – July 2024)
2025Open Access
Transfer learning improves performance in volumetric electron microscopy organelle segmentation across tissues
Bioinformatics Advances·2024· 2 citedOpen Access
Identification of Malignancy in Peritumoral Edema in Soft Tissue Sarcoma: A Novel Targeted Molecular Approach
Annals of Surgical Oncology·2024· 1 cited
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Frequent Co-authors

Gary D. Bader(18), Ian D. McGilvray(17), Tomasz I. Michalak(9), Jawairia Atif(8), Cátia T. Perciani(8), Justin Manuel(7), Sai Chung(7), Tram N. Q. Pham(7), Tallulah Andrews(7), Xue‐Zhong Ma(7), Jordan J. Feld(6), Lewis Liu(5), Mario Ostrowski(5), Cornelia Thoeni(5), Aviv Regev(5), Sarah A. Teichmann(5), Jeff C. Liu(4), Blair K. Gage(4), Nicholas Khuu(4), Juan Echeverri(4)