Karin M. McCarthy

Harvard University — United States

Medicine · Health Sciences

25h-index2.9kcitations44works0.02yr avg
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Research Topics

Sarcoma Diagnosis and Treatment(11), Immunotherapy and Immune Responses(10), T-cell and B-cell Immunology(9), Immune Response and Inflammation(8), Barrier Structure and Function Studies(7)

Publications44 total

Abstract A002: Dynamic single cell imaging of cancer stem cells and clonality in fusion-negative rhabdomyosarcoma
Clinical Cancer Research·2022
Single-cell analysis and functional characterization uncover the stem cell hierarchies and developmental origins of rhabdomyosarcoma
Nature Cancer·2022· 62 citedOpen Access
Therapeutic targeting of LCK tyrosine kinase and mTOR signaling in T-cell acute lymphoblastic leukemia
Blood·2022· 41 citedOpen Access
Single-cell imaging of T cell immunotherapy responses in vivo
The Journal of Experimental Medicine·2021· 24 citedOpen Access
Stem cell hierarchies and developmental origins of rhabdomyosarcoma
Zenodo (CERN European Organization for Nuclear Research)·2021Open Access
Stem cell hierarchies and developmental origins of rhabdomyosarcoma
Zenodo (CERN European Organization for Nuclear Research)·2021Open Access
Stem cell hierarchies and developmental origins of rhabdomyosarcoma
Zenodo (CERN European Organization for Nuclear Research)·2021Open Access
PRL3 enhances T-cell acute lymphoblastic leukemia growth through suppressing T-cell signaling pathways and apoptosis
Leukemia·2020· 25 citedOpen Access
Visualizing Engrafted Human Cancer and Therapy Responses in Immunodeficient Zebrafish
Cell·2019· 254 citedOpen Access
Abstract 3171: Vangl2 regulates cancer stem cell self-renewal and growth in rhabdomyosarcoma
Cancer Research·2018
Vangl2/RhoA Signaling Pathway Regulates Stem Cell Self-Renewal Programs and Growth in Rhabdomyosarcoma
Cell stem cell·2018· 78 citedOpen Access
The NOTCH1/SNAIL1/MEF2C Pathway Regulates Growth and Self-Renewal in Embryonal Rhabdomyosarcoma
Cell Reports·2017· 66 citedOpen Access
Myogenic regulatory transcription factors regulate growth in rhabdomyosarcoma
eLife·2017· 69 citedOpen Access
Author response: Myogenic regulatory transcription factors regulate growth in rhabdomyosarcoma
2016Open Access
Abstract 4733: Notch signaling increases the number of relapse-driving tumor propagating cells in embryonal rhabdomyosarcoma
Cancer Research·2015
Abstract A14: Canonical WNT/β-catenin pathway activation suppresses embryonal rhabdomyosarcoma growth and self-renewal
Molecular Cancer Research·2014
Abstract A67: Canonical WNT/β;-catenin pathway activation suppresses embryonal rhabdomyosarcoma growth and self-renewal
Cancer Research·2014
Glycogen synthase kinase 3 inhibitors induce the canonical WNT/β-catenin pathway to suppress growth and self-renewal in embryonal rhabdomyosarcoma
Proceedings of the National Academy of Sciences·2014· 151 citedOpen Access
Cholesterol efflux stimulates metalloproteinase-mediated cleavage of occludin and release of extracellular membrane particles containing its C-terminal fragments
Experimental Cell Research·2009· 20 cited
Cholesterol depletion alters detergent-specific solubility profiles of selected tight junction proteins and the phosphorylation of occludin
Experimental Cell Research·2007· 43 citedOpen Access
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Frequent Co-authors

Eveline E. Schneeberger(22), David M. Langenau(18), Madeline N. Hayes(11), Chuan Yan(9), Myron S. Ignatius(9), Richard L. Kradin(9), Daniel Do(8), Alexander Jin(8), Sara P. Garcia(8), Eleanor Y. Chen(7), Joanne M. McCormack(6), Javed Khan(6), Yun Wei(6), Qian Qin(6), Robert D. Lynch(5), Riadh Lobbardi(5), Mariana L. Oliveira(5), Sowmya Iyer(5), Sivasish Sindiri(5), Tiffany C.Y. Eng(5)