Eleanor Y. Chen

University of British Columbia — Canada

Medicine · Health Sciences

37h-index3.3kcitations138works2.82yr avg
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Research Topics

Sarcoma Diagnosis and Treatment(67), Cancer-related gene regulation(16), CAR-T cell therapy research(13), Cancer-related molecular mechanisms research(12), Protein Degradation and Inhibitors(12)

Publications138 total

MicroRNA Profiling Identifies Diagnostic and Prognostic Markers in Pediatric Sarcoma
Cancers·2025Open Access
CAR T <sub>reg</sub> cells mediate linked suppression and infectious tolerance in islet transplantation in mice
Science Translational Medicine·2025· 13 cited
Dual Targeting of MAPK Signaling and Senescence-Associated Survival Pathways Overcomes Vincristine Resistance in Fusion-Negative Rhabdomyosarcoma
2025Open Access
Leishmania regulates host YY1: Comparative proteomic analysis identifies infection modulated YY1 dependent proteins
PLoS ONE·2025· 1 citedOpen Access
Abstract 5282: New insights into the roles of transcriptional regulation and differentiation state in rhabdomyosarcoma cell migration
Cancer Research·2025
100 Detection of MYC Amplification by RNA-ISH Strongly Correlates with FISH in Differentiating Post-Radiation Angiosarcoma from Atypical Vascular Lesion
Laboratory Investigation·2025
Genomic Characterization of Chondrosarcoma Reveals Potential Therapeutic Targets
JCO Precision Oncology·2025· 4 citedOpen Access
High-Grade Sarcomatous Transformation of Hybrid Hemosiderotic Fibrolipomatous Tumor-Myxoinflammatory Fibroblastic Sarcoma with Novel <i>ADAMTS12::TERT</i> Gene Fusion
International Journal of Surgical Pathology·2025· 1 cited
Assessing the Utility of DNA Methylation Profiling in the Classification of Myogenic Sarcomas of Bone
International Journal of Surgical Pathology·2025
B7-H3 is widely expressed in soft tissue sarcomas
BMC Cancer·2024· 11 citedOpen Access
Author response for "High-Grade Sarcomatous Transformation of Hybrid Hemosiderotic Fibrolipomatous Tumor-Myxoinflammatory Fibroblastic Sarcoma with Novel &lt;i&gt;ADAMTS12::TERT&lt;/i&gt; Gene Fusion"
2024
Author response for "Assessing the Utility of DNA Methylation Profiling in the Classification of Myogenic Sarcomas of Bone"
2024
Author response for "High-Grade Sarcomatous Transformation of Hybrid Hemosiderotic Fibrolipomatous Tumor-Myxoinflammatory Fibroblastic Sarcoma with Novel &lt;i&gt;ADAMTS12::TERT&lt;/i&gt; Gene Fusion"
2024
HDAC3 genetic and pharmacologic inhibition radiosensitizes fusion positive rhabdomyosarcoma by promoting DNA double-strand breaks
Cell Death Discovery·2024· 8 citedOpen Access
CAR Tregs mediate linked suppression and infectious tolerance in islet transplantation
2024· 6 citedOpen Access
Reclassification of a spindle cell sarcoma after identification of a <scp>TFG‐ROS1</scp> fusion: A case demonstrating the clinical benefit of next‐generation sequencing in sarcoma
Molecular Genetics & Genomic Medicine·2024· 3 citedOpen Access
Abstract 4738: Overcoming therapy resistance in rhabdomyosarcoma by targeting the PI3K-MAPK pathway
Cancer Research·2024
Calcified chondroid mesenchymal neoplasm: report of a case involving the temporomandibular joint region and review of the literature
Oral Surgery Oral Medicine Oral Pathology and Oral Radiology·2024· 4 cited
Calcified Chondroid Mesenchymal Neoplasms
Surgical pathology clinics·2023· 5 cited
Defining function of wild-type and three patient-specific TP53 mutations in a zebrafish model of embryonal rhabdomyosarcoma
eLife·2023· 7 citedOpen Access
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Frequent Co-authors

David M. Langenau(11), Myron S. Ignatius(10), Stephen C. Ekker(9), Javed Khan(6), Charles Keller(5), Michael Phelps(5), José G. Mantilla(5), Robert W. Ricciotti(5), Christopher P. Crum(4), Christopher D.�M. Fletcher(4), Corinne M. Linardic(4), Madeline N. Hayes(4), Berkley E. Gryder(4), Lee D. Cranmer(4), Seth M. Pollack(4), Ryan Clagg(3), Karin M. McCarthy(3), Riadh Lobbardi(3), Catherine M. Verfaillie(3), Jon D. Larson(3)