Ilona S. Skerjanc

University of Ottawa — Canada

Biochemistry, Genetics and Molecular Biology · Life Sciences

36h-index3.9kcitations77works0.02yr avg
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Research Topics

Muscle Physiology and Disorders(26), Tissue Engineering and Regenerative Medicine(17), Pluripotent Stem Cells Research(16), Congenital heart defects research(14), RNA Research and Splicing(12)

Publications76 total

Gene expression profiling of skeletal myogenesis in human embryonic stem cells reveals a potential cascade of transcription factors regulating stages of myogenesis, including quiescent/activated satellite cell-like gene expression
PLoS ONE·2019· 12 citedOpen Access
Combinatorial Utilization of Murine Embryonic Stem Cells and <i>In Vivo</i> Models to Study Human Congenital Heart Disease
Current Protocols in Stem Cell Biology·2018· 1 cited
In Vitro Modeling of Congenital Heart Defects Associated with an NKX2-5 Mutation Revealed a Dysregulation in BMP/Notch-Mediated Signaling
Stem Cells·2017· 12 citedOpen Access
SOX7 Is Required for Muscle Satellite Cell Development and Maintenance
Stem Cell Reports·2017· 9 citedOpen Access
Congenital heart defect causing mutation in Nkx2.5 displays in vivo functional deficit
Journal of Molecular and Cellular Cardiology·2017· 26 cited
BRG1 interacts with GLI2 and binds Mef2c gene in a hedgehog signalling dependent manner during in vitro cardiomyogenesis
BMC Developmental Biology·2016· 3 citedOpen Access
Extracellular Forces Cause the Nucleus to Deform in a Highly Controlled Anisotropic Manner
Scientific Reports·2016· 101 citedOpen Access
Additional file 5: Table S1. of BRG1 interacts with GLI2 and binds Mef2c gene in a hedgehog signalling dependent manner during in vitro cardiomyogenesis
Figshare·2016Open Access
Extracellular Forces Cause the Nucleus to Deform in a Highly Controlled Anisotropic Manner
2015· 3 citedOpen Access
Robust generation and expansion of skeletal muscle progenitors and myocytes from human pluripotent stem cells
Methods·2015· 67 citedOpen Access
Derivation and Expansion of PAX7-Positive Muscle Progenitors from Human and Mouse Embryonic Stem Cells
Stem Cell Reports·2014· 6 citedOpen Access
Derivation and Expansion of PAX7-Positive Muscle Progenitors from Human and Mouse Embryonic Stem Cells
Stem Cell Reports·2014· 178 citedOpen Access
Testosterone enhances cardiomyogenesis in stem cells and recruits the androgen receptor to the MEF2C and HCN4 genes
Journal of Molecular and Cellular Cardiology·2013· 28 cited
β-catenin Is Essential for Efficient In Vitro Premyogenic Mesoderm Formation but Can Be Partially Compensated by Retinoic Acid Signalling
PLoS ONE·2013· 10 citedOpen Access
Hedgehog Signaling Regulates MyoD Expression and Activity
Journal of Biological Chemistry·2012· 59 citedOpen Access
Myosin Phosphatase Modulates the Cardiac Cell Fate by Regulating the Subcellular Localization of Nkx2.5 in a Wnt/Rho–Associated Protein Kinase–Dependent Pathway
Circulation Research·2012· 18 citedOpen Access
Injected matrix stimulates myogenesis and regeneration of mouse skeletal muscle after ischaemic injury
European Cells and Materials·2012· 28 citedOpen Access
Collagen-Based Matrix Pro-Survival miRNA and Regeneration for Improved Function of the Infracted Heart.
2012
Gli2 and MEF2C activate each other's expression and function synergistically during cardiomyogenesis in vitro
Nucleic Acids Research·2011· 43 citedOpen Access
Abstract 12016: An Enhanced Collagen-Based Matrix Promotes Cardiomyocytic Differentiation of Embryonic Stem Cells
Circulation·2011
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Frequent Co-authors

Ashraf Al Madhoun(10), Alan G. Ridgeway(7), Helen Petropoulos(7), Sharon Wilton(7), Anastassia Voronova(6), Michael W. McBurney(5), Michael Shelton(5), Christina Karamboulas(5), Daniel Figeys(4), Junping Liu(4), Virja Mehta(4), Tammy Ryan(4), Marc Ruel(4), Jean‐Philippe Lambert(3), William L. Stanford(3), Valerie A. Wallace(3), Karen A. Kennedy(3), Ruth S. Slack(3), Josée Savage(3), Peter J. Gianakopoulos(3)