Aki Kijima

National Hospital Organization Kyushu Cancer Center — Japan

Biochemistry, Genetics and Molecular Biology · Life Sciences

16h-index570citations51works1.22yr avg
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Research Topics

Carcinogens and Genotoxicity Assessment(22), Genomics, phytochemicals, and oxidative stress(10), DNA Repair Mechanisms(8), Glutathione Transferases and Polymorphisms(7), Bladder and Urothelial Cancer Treatments(4)

Publications51 total

Treatment Outcomes After Progression With Enfortumab Vedotin in Patients With Advanced Urothelial Carcinoma
Anticancer Research·2025· 1 cited
Steroid Premedication Impact on Efficacy and Cutaneous Toxicity of Enfortumab Vedotin for Advanced Urothelial Carcinoma
In Vivo·2025· 1 citedOpen Access
Outcomes of Avelumab Treatment in Advanced Urothelial Carcinoma According to Age, Performance Status, and Timing
In Vivo·2025Open Access
Impact of Relative Dose Intensity of Enfortumab Vedotin for Advanced Urothelial Carcinoma
In Vivo·2024· 3 citedOpen Access
A Case of Metastatic Castration-resistant Prostate Cancer with Tumor Mutation Burden-high Presented Remarkable Response to Atezolizumab
Journal of Precision Oncology·2024
Possible contribution of 8-hydroxydeoxyguanosine to gene mutations in the kidney DNA of gpt delta rats following potassium bromate treatment
Mutation Research/Genetic Toxicology and Environmental Mutagenesis·2024· 2 cited
Toxicity, genotoxicity, and carcinogenicity of 2-methylfuran in a 90-day comprehensive toxicity study in gpt delta rats
Food and Chemical Toxicology·2022· 7 cited
Background data of 2-year-old male and female F344 <i>gpt</i> delta rats
Journal of Toxicologic Pathology·2020· 2 citedOpen Access
Furan Induced Characteristic Glutathione <i>S</i>-Transferase Placental Form-Positive Foci in Terms of Cell Kinetics and Gene Expression
Toxicologic Pathology·2020· 4 cited
DNA modifications that do not cause gene mutations confer the potential for mutagenicity by combined treatment with food chemicals
Food and Chemical Toxicology·2019· 3 cited
Molecular Pathological Differences in Global Gene Expression between Two Sustained Proliferative Lesions, Nodular Regenerative Hepatocellular Hyperplasia and Hepatocellular Adenoma, in Mice
Toxicologic Pathology·2018· 2 cited
Effects of inhibition of hepatic sulfotransferase activity on renal genotoxicity induced by lucidin‐3‐<i>O</i>‐primeveroside
Journal of Applied Toxicology·2018· 4 cited
Requirement of Nrf2 for termination of liver regeneration caused by acute proliferative response
Toxicology Letters·2018
Combined application of comprehensive DNA analysis for DNA modification and reporter gene mutation assay to investigation of the mechanisms underlying hepatocarcinogenicity of elemicin
Toxicology Letters·2018
Mechanisms Underlying Exacerbation of Osmotic Nephrosis Caused by Pre-existing Kidney Injury
Toxicological Sciences·2018· 8 cited
Mechanisms of oxidative stress-induced &lt;i&gt;in vivo&lt;/i&gt; mutagenicity by potassium bromate and nitrofurantoin
Journal of Toxicologic Pathology·2018· 17 citedOpen Access
Role of oxidative stress in the chemical structure-related genotoxicity of nitrofurantoin in &lt;i&gt;Nrf2&lt;/i&gt;-deficient &lt;i&gt;gpt&lt;/i&gt; delta mice
Journal of Toxicologic Pathology·2018· 5 citedOpen Access
Phosphorylation of protein phosphatase 2A facilitated an early stage of chemical carcinogenesis
Toxicology and Applied Pharmacology·2017· 3 cited
In vivo reporter gene mutation and micronucleus assays in gpt delta mice treated with a flame retardant decabromodiphenyl ether
Mutation Research/Genetic Toxicology and Environmental Mutagenesis·2017· 4 cited
Lack of genotoxic mechanisms in early‐stage furan‐induced hepatocellular tumorigenesis in <i>gpt</i> delta rats
Journal of Applied Toxicology·2016· 22 cited
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Frequent Co-authors

Takashi Umemura(44), Shinji Takasu(35), Yuji Ishii(24), Ken Kuroda(22), Kohei Matsushita(21), Takehiko Nohmi(19), Akiyoshi Nishikawa(19), Kumiko Ogawa(15), Yuji Ishii(14), Daisuke Hibi(12), Yuh Yokoo(12), Meilan Jin(11), Takuma Tsuchiya(9), Yukio Kodama(9), Ying‐Chin Ko(8), Yuta Suzuki(7), Tokuma Yanai(7), Yuji Ishii(5), Tomoki Inoue(5), Yoshiko Sugita‐Konishi(4)