Melchiorre Cervello

National Research Council — Romania

Biochemistry, Genetics and Molecular Biology · Life Sciences

50h-index9.9kcitations195works3.62yr avg
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Research Topics

PI3K/AKT/mTOR signaling in cancer(21), Cancer-related Molecular Pathways(17), Liver Disease Diagnosis and Treatment(15), Inflammatory mediators and NSAID effects(15), Cancer Mechanisms and Therapy(15)

Publications195 total

Structure-based identification of a non-covalent thioredoxin reductase inhibitor with proven ADMET suitability
Journal of Enzyme Inhibition and Medicinal Chemistry·2025Open Access
Correction: Novel Combination of Sorafenib and Celecoxib Provides Synergistic Anti-Proliferative and Pro-Apoptotic Effects in Human Liver Cancer Cells
PLoS ONE·2025Open Access
Structure-based identification of the first non-covalent thioredoxin reductase inhibitor with proven ADMET suitability
2025· 1 cited
A Bde-47/Estrone Mixture Modulates Macrophage Immune Responses and Mirna Networks, Impairs Intestinal Barrier Integrity in Vitro, and Alters Circulating Mirnas and Tight Junction Expression in Vivo
SSRN Electronic Journal·2025Open Access
TP53 gene status can promote sensitivity and resistance to chemotherapeutic drugs and small molecule signal transduction inhibitors
Advances in Biological Regulation·2024· 2 citedOpen Access
Photoaging of polystyrene-based microplastics amplifies inflammatory response in macrophages
Chemosphere·2024· 15 citedOpen Access
TOP-193 Consumption of a mediterranean diet with high-polyphenol content extra-virgin olive oil (EVOO) in patients with MASLD: effects on clinical parameters and gene expression on peripheral blood mononuclear cells (PBMCs)
Journal of Hepatology·2024
The potential of the nutraceutical berberine in the treatment of hepatocellular carcinoma and other liver diseases such as NAFLD and NASH
Advances in Biological Regulation·2024· 7 cited
Extracellular Vesicle-Related Non-Coding RNAs in Hepatocellular Carcinoma: An Overview
Cancers·2024· 9 citedOpen Access
Genetic Biomarkers of Sorafenib Response in Patients with Hepatocellular Carcinoma
International Journal of Molecular Sciences·2024· 6 citedOpen Access
Photoaging of Polystyrene-Based Microplastics Amplifies Inflammatory Response in Macrophages
SSRN Electronic Journal·2024Open Access
Genetic biomarkers of sorafenib response in patients with hepatocellular carcinoma
2023Open Access
Genetic biomarkers for sorafenib response in patients with hepatocellular carcinoma
Journal of Hepatology·2023
New Insights into the Behavior of NHC-Gold Complexes in Cancer Cells
Pharmaceutics·2023· 25 citedOpen Access
Can Baseline IL-6 Levels Predict Long COVID in Subjects Hospitalized for SARS-CoV-2 Disease?
International Journal of Molecular Sciences·2023· 17 citedOpen Access
Effects of chloroquine and hydroxychloroquine on the sensitivity of pancreatic cancer cells to targeted therapies
Advances in Biological Regulation·2022· 9 citedOpen Access
The clinical impact of an extra virgin olive oil enriched mediterranean diet on metabolic syndrome: Lights and shadows of a nutraceutical approach
Frontiers in Nutrition·2022· 30 citedOpen Access
Effects of TP53 Mutations and miRs on Immune Responses in the Tumor Microenvironment Important in Pancreatic Cancer Progression
Cells·2022· 47 citedOpen Access
Outcome predictors in SARS-CoV-2 disease (COVID-19): The prominent role of IL-6 levels and an IL-6 gene polymorphism in a western Sicilian population
Journal of Infection·2022· 15 citedOpen Access
Effects of the Mutant TP53 Reactivator APR-246 on Therapeutic Sensitivity of Pancreatic Cancer Cells in the Presence and Absence of WT-TP53
Cells·2022· 17 citedOpen Access
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Frequent Co-authors

Giuseppe Montalto(38), James A. McCubrey(30), Linda S. Steelman(23), Massimo Libra(21), Alberto M. Martelli(20), Lucio Cocco(17), Stephen L. Abrams(15), Ferdinando Nicoletti(14), Antonina Azzolina(13), Saverio Candido(11), Antonella Cusimano(10), Maria Rita Emma(10), Giuseppa Augello(10), Jörg Bäsecke(9), Agnieszka Gizak(8), William H. Chappell(7), Michèle Milella(7), Agostino Tafuri(7), Lydia Giannitrapani(7), Kvin Lertpiriyapong(7)